File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1021/acsami.9b06382
- Scopus: eid_2-s2.0-85068146983
- PMID: 31145590
- WOS: WOS:000473251100089
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: All-Aqueous Thin-film-flow-induced Cell-based Monolayers
Title | All-Aqueous Thin-film-flow-induced Cell-based Monolayers |
---|---|
Authors | |
Keywords | all-aqueous system assembly dextran poly(ethylene glycol) (PEG) interfaces |
Issue Date | 2019 |
Publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/aamick |
Citation | ACS Applied Materials & Interfaces, 2019, v. 11 n. 25, p. 22869-22877 How to Cite? |
Abstract | Cells in vitro usually require a solid scaffold to attach and form two-dimensional monolayer structures. To obtain a substrate-free cell monolayer, long culture time and specific detaching procedures are required. In this study, a thin-film-flow-induced strategy is reported to overcome the challenges of assembling in vitro scaffold-free monolayered cell aggregates. The assembly is driven by a dewetting-like thin-film withdrawal along all-aqueous interfaces characterized by a low interfacial tension. The withdrawal process drives the cells adsorbed on the liquid film to aggregate and assemble into an organized and compact monolayer. This strategy is not limited to biological cells but also colloidal particles, as demonstrated by the assembly of hybrid cell–particle monolayers. The versatility offered by this approach suggests new opportunities in understanding early tissue formation and functionalizing cell monolayer aggregates by colloidal particles with customized functions. |
Persistent Identifier | http://hdl.handle.net/10722/273390 |
ISSN | 2023 Impact Factor: 8.3 2023 SCImago Journal Rankings: 2.058 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chan, YK | - |
dc.contributor.author | YAN, WH | - |
dc.contributor.author | HUNG, LT | - |
dc.contributor.author | CHAO, Y | - |
dc.contributor.author | WU, J | - |
dc.contributor.author | Shum, HC | - |
dc.date.accessioned | 2019-08-06T09:28:02Z | - |
dc.date.available | 2019-08-06T09:28:02Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | ACS Applied Materials & Interfaces, 2019, v. 11 n. 25, p. 22869-22877 | - |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | http://hdl.handle.net/10722/273390 | - |
dc.description.abstract | Cells in vitro usually require a solid scaffold to attach and form two-dimensional monolayer structures. To obtain a substrate-free cell monolayer, long culture time and specific detaching procedures are required. In this study, a thin-film-flow-induced strategy is reported to overcome the challenges of assembling in vitro scaffold-free monolayered cell aggregates. The assembly is driven by a dewetting-like thin-film withdrawal along all-aqueous interfaces characterized by a low interfacial tension. The withdrawal process drives the cells adsorbed on the liquid film to aggregate and assemble into an organized and compact monolayer. This strategy is not limited to biological cells but also colloidal particles, as demonstrated by the assembly of hybrid cell–particle monolayers. The versatility offered by this approach suggests new opportunities in understanding early tissue formation and functionalizing cell monolayer aggregates by colloidal particles with customized functions. | - |
dc.language | eng | - |
dc.publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/aamick | - |
dc.relation.ispartof | ACS Applied Materials & Interfaces | - |
dc.rights | This document is the Accepted Manuscript version of a Published Work that appeared in final form in [JournalTitle], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [insert ACS Articles on Request author-directed link to Published Work, see http://pubs.acs.org/page/policy/articlesonrequest/index.html]. | - |
dc.subject | all-aqueous system | - |
dc.subject | assembly | - |
dc.subject | dextran | - |
dc.subject | poly(ethylene glycol) (PEG) | - |
dc.subject | interfaces | - |
dc.title | All-Aqueous Thin-film-flow-induced Cell-based Monolayers | - |
dc.type | Article | - |
dc.identifier.email | Chan, YK: josephyk@connect.hku.hk | - |
dc.identifier.email | Shum, HC: ashum@hku.hk | - |
dc.identifier.authority | Chan, YK=rp02536 | - |
dc.identifier.authority | Shum, HC=rp01439 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1021/acsami.9b06382 | - |
dc.identifier.pmid | 31145590 | - |
dc.identifier.scopus | eid_2-s2.0-85068146983 | - |
dc.identifier.hkuros | 300872 | - |
dc.identifier.volume | 11 | - |
dc.identifier.issue | 25 | - |
dc.identifier.spage | 22869 | - |
dc.identifier.epage | 22877 | - |
dc.identifier.isi | WOS:000473251100089 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1944-8244 | - |