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Article: Two antimycin A analogues from marine-derived actinomycete Streptomyces lusitanus

TitleTwo antimycin A analogues from marine-derived actinomycete Streptomyces lusitanus
Authors
Han, ZhuangXu, YingMcConnell, OliverLiu, LingliLi, YongxinQi, ShuhuaHuang, XiangzhongQian, Peiyuan
KeywordsAntimycin B
Antibacterial
Marine-derived actinomycete
Streptomyces lusitanus
Issue Date2012
Citation
Marine Drugs, 2012, v. 10, n. 3, p. 668-676 How to Cite?
DOI: http://dx.doi.org/10.3390/md10030668
AbstractTwo new antimycin A analogues, antimycin B1 and B2 (1-2), were isolated from a spent broth of a marine-derived bacterium, Streptomyces lusitanus. The structures of 1 and 2 were established on the basis of spectroscopic analyses and chemical methods. The isolated compounds were tested for their anti-bacterial potency. Compound 1 was found to be inactive against the bacteria Bacillus subtilis, Staphyloccocus aureus, and Loktanella hongkongensis. Compound 2 showed antibacterial activities against S. aureus and L. hongkongensis with MIC values of 32.0 and 8.0 μg/mL, respectively. © 2012 by the authors; licensee MDPI.
Persistent Identifierhttp://hdl.handle.net/10722/273514
ISSN
1660-3397
2021 Impact Factor: 6.085
2020 SCImago Journal Rankings: 0.848
ISI Accession Number ID
WOS:000302136700012

 

DC FieldValueLanguage
dc.contributor.authorHan, Zhuang-
dc.contributor.authorXu, Ying-
dc.contributor.authorMcConnell, Oliver-
dc.contributor.authorLiu, Lingli-
dc.contributor.authorLi, Yongxin-
dc.contributor.authorQi, Shuhua-
dc.contributor.authorHuang, Xiangzhong-
dc.contributor.authorQian, Peiyuan-
dc.date.accessioned2019-08-12T09:55:48Z-
dc.date.available2019-08-12T09:55:48Z-
dc.date.issued2012-
dc.identifier.citationMarine Drugs, 2012, v. 10, n. 3, p. 668-676-
dc.identifier.issn1660-3397-
dc.identifier.urihttp://hdl.handle.net/10722/273514-
dc.description.abstractTwo new antimycin A analogues, antimycin B1 and B2 (1-2), were isolated from a spent broth of a marine-derived bacterium, Streptomyces lusitanus. The structures of 1 and 2 were established on the basis of spectroscopic analyses and chemical methods. The isolated compounds were tested for their anti-bacterial potency. Compound 1 was found to be inactive against the bacteria Bacillus subtilis, Staphyloccocus aureus, and Loktanella hongkongensis. Compound 2 showed antibacterial activities against S. aureus and L. hongkongensis with MIC values of 32.0 and 8.0 μg/mL, respectively. © 2012 by the authors; licensee MDPI.-
dc.languageeng-
dc.relation.ispartofMarine Drugs-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAntimycin B-
dc.subjectAntibacterial-
dc.subjectMarine-derived actinomycete-
dc.subjectStreptomyces lusitanus-
dc.titleTwo antimycin A analogues from marine-derived actinomycete Streptomyces lusitanus-
dc.typeArticle-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3390/md10030668-
dc.identifier.pmid22611362-
dc.identifier.scopuseid_2-s2.0-84859569940-
dc.identifier.volume10-
dc.identifier.issue3-
dc.identifier.spage668-
dc.identifier.epage676-
dc.identifier.isiWOS:000302136700012-
dc.identifier.issnl1660-3397-

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