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Article: Repair of dentine-related lesions without a drill or injection
Title | Repair of dentine-related lesions without a drill or injection |
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Authors | |
Keywords | Electric fields Microhardness In-vivo Inflammatory reaction Remineralization |
Issue Date | 2019 |
Publisher | Royal Society of Chemistry: Open Access. The Journal's web site is located at http://pubs.rsc.org/en/journals/journalissues/ra |
Citation | RSC Advances, 2019, v. 9 n. 26, p. 15099-15107 How to Cite? |
Abstract | For covering the shortages of traditional treatments, a novel and non-invasive system was developed with the simple adaption of nature's own repair process, while an extrinsic electric field was introduced to improve its remineralization kinetics. In an in vivo study, acid-etched rabbit dentine was used to evaluate the remineralization efficacy and safety of the system. The exposed dentine tubules were fully occluded after 5 hours/1.0 mA and 8 hours/0.5 mA of remineralization. After 5 hours of remineralization (1.0 mA), the micro-hardness of the demineralized dentine was fully recovered, equal to native rabbit dentine. Haematoxylin–eosin staining demonstrated no obvious inflammatory reaction. This study provides a feasible solution to realize rapid repair of dentine. |
Persistent Identifier | http://hdl.handle.net/10722/273826 |
ISSN | 2023 Impact Factor: 3.9 2023 SCImago Journal Rankings: 0.715 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Zhang, YY | - |
dc.contributor.author | Wong, HM | - |
dc.contributor.author | McGrath, CPJ | - |
dc.contributor.author | Li, QL | - |
dc.date.accessioned | 2019-08-18T14:49:20Z | - |
dc.date.available | 2019-08-18T14:49:20Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | RSC Advances, 2019, v. 9 n. 26, p. 15099-15107 | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.uri | http://hdl.handle.net/10722/273826 | - |
dc.description.abstract | For covering the shortages of traditional treatments, a novel and non-invasive system was developed with the simple adaption of nature's own repair process, while an extrinsic electric field was introduced to improve its remineralization kinetics. In an in vivo study, acid-etched rabbit dentine was used to evaluate the remineralization efficacy and safety of the system. The exposed dentine tubules were fully occluded after 5 hours/1.0 mA and 8 hours/0.5 mA of remineralization. After 5 hours of remineralization (1.0 mA), the micro-hardness of the demineralized dentine was fully recovered, equal to native rabbit dentine. Haematoxylin–eosin staining demonstrated no obvious inflammatory reaction. This study provides a feasible solution to realize rapid repair of dentine. | - |
dc.language | eng | - |
dc.publisher | Royal Society of Chemistry: Open Access. The Journal's web site is located at http://pubs.rsc.org/en/journals/journalissues/ra | - |
dc.relation.ispartof | RSC Advances | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Electric fields | - |
dc.subject | Microhardness | - |
dc.subject | In-vivo | - |
dc.subject | Inflammatory reaction | - |
dc.subject | Remineralization | - |
dc.title | Repair of dentine-related lesions without a drill or injection | - |
dc.type | Article | - |
dc.identifier.email | Wong, HM: wonghmg@hkucc.hku.hk | - |
dc.identifier.email | McGrath, CPJ: mcgrathc@hkucc.hku.hk | - |
dc.identifier.authority | Wong, HM=rp00042 | - |
dc.identifier.authority | McGrath, CPJ=rp00037 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1039/C9RA02759A | - |
dc.identifier.scopus | eid_2-s2.0-85065864293 | - |
dc.identifier.hkuros | 301887 | - |
dc.identifier.volume | 9 | - |
dc.identifier.issue | 26 | - |
dc.identifier.spage | 15099 | - |
dc.identifier.epage | 15107 | - |
dc.identifier.isi | WOS:000468641300060 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 2046-2069 | - |