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Article: Ligand-Enabled Stereoselective β-C(sp3)-H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids

TitleLigand-Enabled Stereoselective β-C(sp3)-H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids
Authors
Issue Date2015
Citation
Journal of the American Chemical Society, 2015, v. 137, n. 22, p. 7067-7070 How to Cite?
Abstract© 2015 American Chemical Society. A quinoline-based ligand was shown to promote palladium-catalyzed β-C(sp3)-H fluorination for the first time. A range of unnatural enantiopure fluorinated α-amino acids were obtained through sequential β-C(sp3)-H arylation and subsequent stereoselective fluorination from readily available l-alanine.
Persistent Identifierhttp://hdl.handle.net/10722/276691
ISSN
2023 Impact Factor: 14.4
2023 SCImago Journal Rankings: 5.489
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorZhu, Ru Yi-
dc.contributor.authorTanaka, Keita-
dc.contributor.authorLi, Gen Cheng-
dc.contributor.authorHe, Jian-
dc.contributor.authorFu, Hai Yan-
dc.contributor.authorLi, Su Hua-
dc.contributor.authorYu, Jin Quan-
dc.date.accessioned2019-09-18T08:34:22Z-
dc.date.available2019-09-18T08:34:22Z-
dc.date.issued2015-
dc.identifier.citationJournal of the American Chemical Society, 2015, v. 137, n. 22, p. 7067-7070-
dc.identifier.issn0002-7863-
dc.identifier.urihttp://hdl.handle.net/10722/276691-
dc.description.abstract© 2015 American Chemical Society. A quinoline-based ligand was shown to promote palladium-catalyzed β-C(sp3)-H fluorination for the first time. A range of unnatural enantiopure fluorinated α-amino acids were obtained through sequential β-C(sp3)-H arylation and subsequent stereoselective fluorination from readily available l-alanine.-
dc.languageeng-
dc.relation.ispartofJournal of the American Chemical Society-
dc.titleLigand-Enabled Stereoselective β-C(sp3)-H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/jacs.5b04088-
dc.identifier.pmid26001406-
dc.identifier.scopuseid_2-s2.0-84935069572-
dc.identifier.volume137-
dc.identifier.issue22-
dc.identifier.spage7067-
dc.identifier.epage7070-
dc.identifier.eissn1520-5126-
dc.identifier.isiWOS:000356322300024-
dc.identifier.issnl0002-7863-

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