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- Publisher Website: 10.1016/j.bpobgyn.2019.01.003
- Scopus: eid_2-s2.0-85061980593
- PMID: 30819578
- WOS: WOS:000484653900008
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Article: Congenital urinary tract obstruction
Title | Congenital urinary tract obstruction |
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Authors | |
Keywords | Congenital abnormalities Fetal therapy Prenatal ultrasonography Urinary bladder neck obstruction |
Issue Date | 2019 |
Publisher | Bailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn |
Citation | Best Practice & Research: Clinical Obstetrics & Gynaecology, 2019, v. 58, p. 78-92 How to Cite? |
Abstract | Congenital bladder neck obstruction (or lower urinary tract obstruction [LUTO]) describes a heterogeneous group of congenital anomalies presenting with similar prenatal ultrasonographic findings of dilated posterior urethra, megacystis, hydronephrosis, oligohydramnios and often with associated renal dysplasia. Untreated LUTO has high rate of perinatal morbidity and mortality from associated pulmonary hypoplasia and early-onset renal failure in infancy. Ultrasonographic features and prospective fetal urinalysis may help in predicting the overall prognosis of congenital LUTO. Currently, fetal vesicoamniotic shunt (of various designs), and fetal cystoscopy and fulguration of the obstruction are potential prenatal interventions. Retrospective and prospective cohort studies and a relatively small randomized controlled trial have demonstrated these treatments may possibly improve perinatal survival. Despite this, concerns remain as to the high rates of renal impairment observed in paediatric survivors. A clinical prospective scoring/staging system may improve prenatal diagnostic criteria and case selection for fetal therapy. |
Persistent Identifier | http://hdl.handle.net/10722/277777 |
ISSN | 2023 Impact Factor: 3.9 2023 SCImago Journal Rankings: 1.532 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Cheung, KW | - |
dc.contributor.author | Morris, RK | - |
dc.contributor.author | Kilby, MD | - |
dc.date.accessioned | 2019-10-04T08:01:09Z | - |
dc.date.available | 2019-10-04T08:01:09Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Best Practice & Research: Clinical Obstetrics & Gynaecology, 2019, v. 58, p. 78-92 | - |
dc.identifier.issn | 1521-6934 | - |
dc.identifier.uri | http://hdl.handle.net/10722/277777 | - |
dc.description.abstract | Congenital bladder neck obstruction (or lower urinary tract obstruction [LUTO]) describes a heterogeneous group of congenital anomalies presenting with similar prenatal ultrasonographic findings of dilated posterior urethra, megacystis, hydronephrosis, oligohydramnios and often with associated renal dysplasia. Untreated LUTO has high rate of perinatal morbidity and mortality from associated pulmonary hypoplasia and early-onset renal failure in infancy. Ultrasonographic features and prospective fetal urinalysis may help in predicting the overall prognosis of congenital LUTO. Currently, fetal vesicoamniotic shunt (of various designs), and fetal cystoscopy and fulguration of the obstruction are potential prenatal interventions. Retrospective and prospective cohort studies and a relatively small randomized controlled trial have demonstrated these treatments may possibly improve perinatal survival. Despite this, concerns remain as to the high rates of renal impairment observed in paediatric survivors. A clinical prospective scoring/staging system may improve prenatal diagnostic criteria and case selection for fetal therapy. | - |
dc.language | eng | - |
dc.publisher | Bailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn | - |
dc.relation.ispartof | Best Practice & Research: Clinical Obstetrics & Gynaecology | - |
dc.subject | Congenital abnormalities | - |
dc.subject | Fetal therapy | - |
dc.subject | Prenatal ultrasonography | - |
dc.subject | Urinary bladder neck obstruction | - |
dc.title | Congenital urinary tract obstruction | - |
dc.type | Article | - |
dc.identifier.email | Cheung, KW: kawang@HKUCC-COM.hku.hk | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.bpobgyn.2019.01.003 | - |
dc.identifier.pmid | 30819578 | - |
dc.identifier.scopus | eid_2-s2.0-85061980593 | - |
dc.identifier.hkuros | 306800 | - |
dc.identifier.volume | 58 | - |
dc.identifier.spage | 78 | - |
dc.identifier.epage | 92 | - |
dc.identifier.isi | WOS:000484653900008 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 1521-6934 | - |