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Article: Psychiatrists' opinion towards medication discontinuation in remitted first-episode psychosis: A multi-site study of the Asian Network for Early Psychosis

TitlePsychiatrists' opinion towards medication discontinuation in remitted first-episode psychosis: A multi-site study of the Asian Network for Early Psychosis
Authors
KeywordsAsian Network for Early Psychosis
first-episode psychosis
medication discontinuation
relapse
remission
Issue Date2019
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1751-7893
Citation
Early Intervention in Psychiatry, 2019, v. 13 n. 6, p. 1329-1337 How to Cite?
AbstractAim:The study investigated psychiatrists' views towards the issue of medication discontinuationfor patients in remission from first-episode psychosis in four countries (Hong Kong, Korea, Sin-gapore and Japan) that are part of the Asian Network for Early Psychosis, focusing on whetherthe views of these countries differ with one another.Methods:A questionnaire was distributed to psychiatrists for completion. The questionnairecontained three sections: direct questions probing at views on medication discontinuation, casevignettes to assess applied decision-making and a checklist of criteria psychiatrists may view asnecessary for the patient to satisfy before discontinuation. Total of 484 psychiatrists (97 fromHong Kong, 88 from Korea, 64 from Singapore and 233 from Japan) completed thequestionnaire.Results:We found that (a) Asian psychiatrists believed that 1% to 19% of remitted patients candiscontinue medication, an estimation that was lower than Western psychiatrists; (b) in agree-ment with clinical guidelines, Asian psychiatrists believed that patients should remain on medi-cation for at least 1 to 2 years following the absence of psychotic symptoms; (c)“Absence ofany relapsing episode following first episode”was considered the most important criterion whenmaking a decision; and (d) there were significant differences in clinicians' perceptions across thefour countries: for instance, Korean psychiatrists were more conservative with the duration ofantipsychotics maintenance, while Singaporean psychiatrists were more open-minded towardsclinical trials.Conclusions:Culture and social norms appear to determine the relative importance of factorsthat psychiatrists might consider during the decision-making process, thereby producing varia-tions in the views held in different countries.
Persistent Identifierhttp://hdl.handle.net/10722/278613
ISSN
2020 Impact Factor: 2.732
2015 SCImago Journal Rankings: 1.071
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHui, CLM-
dc.contributor.authorWong, AKH-
dc.contributor.authorLeung, WWT-
dc.contributor.authorLee, EHM-
dc.contributor.authorChan, SKW-
dc.contributor.authorChang, WC-
dc.contributor.authorChen, EYH-
dc.contributor.authorChan, TCT-
dc.contributor.authorSwapna, V-
dc.contributor.authorTagata, H-
dc.contributor.authorTsujino, N-
dc.contributor.authorNemoto, T-
dc.contributor.authorMizuno, M-
dc.contributor.authorKang , NI-
dc.contributor.authorKim, SW-
dc.contributor.authorChung, YC-
dc.date.accessioned2019-10-21T02:10:48Z-
dc.date.available2019-10-21T02:10:48Z-
dc.date.issued2019-
dc.identifier.citationEarly Intervention in Psychiatry, 2019, v. 13 n. 6, p. 1329-1337-
dc.identifier.issn1751-7885-
dc.identifier.urihttp://hdl.handle.net/10722/278613-
dc.description.abstractAim:The study investigated psychiatrists' views towards the issue of medication discontinuationfor patients in remission from first-episode psychosis in four countries (Hong Kong, Korea, Sin-gapore and Japan) that are part of the Asian Network for Early Psychosis, focusing on whetherthe views of these countries differ with one another.Methods:A questionnaire was distributed to psychiatrists for completion. The questionnairecontained three sections: direct questions probing at views on medication discontinuation, casevignettes to assess applied decision-making and a checklist of criteria psychiatrists may view asnecessary for the patient to satisfy before discontinuation. Total of 484 psychiatrists (97 fromHong Kong, 88 from Korea, 64 from Singapore and 233 from Japan) completed thequestionnaire.Results:We found that (a) Asian psychiatrists believed that 1% to 19% of remitted patients candiscontinue medication, an estimation that was lower than Western psychiatrists; (b) in agree-ment with clinical guidelines, Asian psychiatrists believed that patients should remain on medi-cation for at least 1 to 2 years following the absence of psychotic symptoms; (c)“Absence ofany relapsing episode following first episode”was considered the most important criterion whenmaking a decision; and (d) there were significant differences in clinicians' perceptions across thefour countries: for instance, Korean psychiatrists were more conservative with the duration ofantipsychotics maintenance, while Singaporean psychiatrists were more open-minded towardsclinical trials.Conclusions:Culture and social norms appear to determine the relative importance of factorsthat psychiatrists might consider during the decision-making process, thereby producing varia-tions in the views held in different countries.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1751-7893-
dc.relation.ispartofEarly Intervention in Psychiatry-
dc.rightsPreprint This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Postprint This is the peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.-
dc.subjectAsian Network for Early Psychosis-
dc.subjectfirst-episode psychosis-
dc.subjectmedication discontinuation-
dc.subjectrelapse-
dc.subjectremission-
dc.titlePsychiatrists' opinion towards medication discontinuation in remitted first-episode psychosis: A multi-site study of the Asian Network for Early Psychosis-
dc.typeArticle-
dc.identifier.emailHui, CLM: christyh@hku.hk-
dc.identifier.emailWong, AKH: andreasw@hku.hk-
dc.identifier.emailLee, EHM: edwinlhm@hku.hk-
dc.identifier.emailChan, SKW: kwsherry@hku.hk-
dc.identifier.emailChang, WC: changwc@hku.hk-
dc.identifier.emailChen, EYH: eyhchen@hku.hk-
dc.identifier.authorityHui, CLM=rp01993-
dc.identifier.authorityLee, EHM=rp01575-
dc.identifier.authorityChan, SKW=rp00539-
dc.identifier.authorityChang, WC=rp01465-
dc.identifier.authorityChen, EYH=rp00392-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/eip.12765-
dc.identifier.pmid30485671-
dc.identifier.scopuseid_2-s2.0-85057863827-
dc.identifier.hkuros307261-
dc.identifier.volume13-
dc.identifier.issue6-
dc.identifier.spage1329-
dc.identifier.epage1337-
dc.identifier.isiWOS:000497120500004-
dc.publisher.placeUnited States-
dc.identifier.issnl1751-7885-

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