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Conference Paper: Differential cortical thinning of auditory cortex in first episode schizophrenia: association with auditory verbal hallucinations

TitleDifferential cortical thinning of auditory cortex in first episode schizophrenia: association with auditory verbal hallucinations
Authors
Issue Date2018
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1751-7893
Citation
The 11th International Conference on Early Intervention in Mental Health: Prevention and Early Intervention: Broadening the Scope (IEPA 11), Boston, USA, 7-10 October 2018. In Early Intervention in Psychiatry, 2018, v. 12 n. Suppl. 1, p. 164 How to Cite?
AbstractBackground. Patients with chronic schizophrenia and persistent auditory verbal hallucination (AVH) are found to have reduced cortical thickness in auditory cortex. The role of cortical thickness in pathogenesis of AVH among first episode treatment responsive patients is not clear yet. We compared the cortical thickness of auditory cortex in first episode schizophrenia patients with and without AVH in this study. Method. We measured the cortical thicknesses of 34 right-handed patients (17 AVH+, 17 AVH–) using T1-weighted MPRAGE structural MRI images and compared them after propensity score matching. Results. AVH+ group had significantly lower cortical thickness in left superior temporal sulcus than AVH– group. The left superior temporal sulcus cortical thickness was negatively associated with auditory hallucinations score. Conclusions. Our finding of decreased cortical thickness in the left superior temporal sulcus provides further evidence about the involvement of auditory cortex in the pathogenesis of AVH in schizophrenia.
DescriptionPoster Session B: no. B46
Persistent Identifierhttp://hdl.handle.net/10722/278747
ISSN
2023 Impact Factor: 2.1
2023 SCImago Journal Rankings: 0.976

 

DC FieldValueLanguage
dc.contributor.authorLee, HME-
dc.contributor.authorHui, CLM-
dc.contributor.authorChang, WC-
dc.contributor.authorChan, KW-
dc.contributor.authorCamchong, JY-
dc.contributor.authorLim, K-
dc.contributor.authorChen, EYH-
dc.date.accessioned2019-10-21T02:13:19Z-
dc.date.available2019-10-21T02:13:19Z-
dc.date.issued2018-
dc.identifier.citationThe 11th International Conference on Early Intervention in Mental Health: Prevention and Early Intervention: Broadening the Scope (IEPA 11), Boston, USA, 7-10 October 2018. In Early Intervention in Psychiatry, 2018, v. 12 n. Suppl. 1, p. 164-
dc.identifier.issn1751-7885-
dc.identifier.urihttp://hdl.handle.net/10722/278747-
dc.descriptionPoster Session B: no. B46-
dc.description.abstractBackground. Patients with chronic schizophrenia and persistent auditory verbal hallucination (AVH) are found to have reduced cortical thickness in auditory cortex. The role of cortical thickness in pathogenesis of AVH among first episode treatment responsive patients is not clear yet. We compared the cortical thickness of auditory cortex in first episode schizophrenia patients with and without AVH in this study. Method. We measured the cortical thicknesses of 34 right-handed patients (17 AVH+, 17 AVH–) using T1-weighted MPRAGE structural MRI images and compared them after propensity score matching. Results. AVH+ group had significantly lower cortical thickness in left superior temporal sulcus than AVH– group. The left superior temporal sulcus cortical thickness was negatively associated with auditory hallucinations score. Conclusions. Our finding of decreased cortical thickness in the left superior temporal sulcus provides further evidence about the involvement of auditory cortex in the pathogenesis of AVH in schizophrenia.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1751-7893-
dc.relation.ispartofEarly Intervention in Psychiatry-
dc.relation.ispartofInternational Conference on Early Intervention in Mental Health (IEPA 11), 2018-
dc.titleDifferential cortical thinning of auditory cortex in first episode schizophrenia: association with auditory verbal hallucinations-
dc.typeConference_Paper-
dc.identifier.emailLee, HME: edwinlhm@hku.hk-
dc.identifier.emailHui, CLM: christyh@hku.hk-
dc.identifier.emailChang, WC: changwc@hku.hk-
dc.identifier.emailChan, KW: kwsherry@hku.hk-
dc.identifier.emailChen, EYH: eyhchen@hku.hk-
dc.identifier.authorityLee, HME=rp01575-
dc.identifier.authorityHui, CLM=rp01993-
dc.identifier.authorityChang, WC=rp01465-
dc.identifier.authorityChan, KW=rp00539-
dc.identifier.authorityChen, EYH=rp00392-
dc.identifier.hkuros307301-
dc.identifier.volume12-
dc.identifier.issueSuppl. 1-
dc.identifier.spage164-
dc.identifier.epage164-
dc.publisher.placeUnited States-
dc.identifier.issnl1751-7885-

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