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Article: Oral Epstein-Barr virus-positive mucocutaneous ulcer: gingival presentation of a benign lymphoproliferative lesion
Title | Oral Epstein-Barr virus-positive mucocutaneous ulcer: gingival presentation of a benign lymphoproliferative lesion |
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Authors | |
Keywords | Epstein–Barr virus mucocutaneous ulcer lymphoproliferative disorder |
Issue Date | 2020 |
Publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijom |
Citation | International Journal of Oral and Maxillofacial Surgery, 2020, v. 49 n. 10, p. 1351-1354 How to Cite? |
Abstract | Epstein–Barr virus-positive mucocutaneous ulcer (EBVMCU) is a benign lymphoproliferative lesion related to iatrogenic or age-related immunosuppression in patients with prior Epstein–Barr virus (EBV) infection. Although the clinical presentation may resemble malignant disease, the course of EBVMCU is indolent, and regression is expected when immunosuppression is reduced. We present a case of EBVMCU in the gingiva of a 59-year-old male patient with long-standing pemphigus vulgaris. The initial presentation was suspicious for oral cavity cancer, which was ruled out by biopsy. After reduction of immunosuppression, the ulceration regressed and an area of exposed necrotic bone remained. Complete healing was achieved after sequestrectomy and primary closure with a local gingival flap. |
Persistent Identifier | http://hdl.handle.net/10722/281868 |
ISSN | 2023 Impact Factor: 2.2 2023 SCImago Journal Rankings: 0.875 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Li, DTS | - |
dc.contributor.author | Lo, AWI | - |
dc.contributor.author | Su, Y-X | - |
dc.date.accessioned | 2020-04-03T07:22:55Z | - |
dc.date.available | 2020-04-03T07:22:55Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | International Journal of Oral and Maxillofacial Surgery, 2020, v. 49 n. 10, p. 1351-1354 | - |
dc.identifier.issn | 0901-5027 | - |
dc.identifier.uri | http://hdl.handle.net/10722/281868 | - |
dc.description.abstract | Epstein–Barr virus-positive mucocutaneous ulcer (EBVMCU) is a benign lymphoproliferative lesion related to iatrogenic or age-related immunosuppression in patients with prior Epstein–Barr virus (EBV) infection. Although the clinical presentation may resemble malignant disease, the course of EBVMCU is indolent, and regression is expected when immunosuppression is reduced. We present a case of EBVMCU in the gingiva of a 59-year-old male patient with long-standing pemphigus vulgaris. The initial presentation was suspicious for oral cavity cancer, which was ruled out by biopsy. After reduction of immunosuppression, the ulceration regressed and an area of exposed necrotic bone remained. Complete healing was achieved after sequestrectomy and primary closure with a local gingival flap. | - |
dc.language | eng | - |
dc.publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijom | - |
dc.relation.ispartof | International Journal of Oral and Maxillofacial Surgery | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Epstein–Barr virus | - |
dc.subject | mucocutaneous ulcer | - |
dc.subject | lymphoproliferative disorder | - |
dc.title | Oral Epstein-Barr virus-positive mucocutaneous ulcer: gingival presentation of a benign lymphoproliferative lesion | - |
dc.type | Article | - |
dc.identifier.email | Li, DTS: diontsli@hku.hk | - |
dc.identifier.email | Su, Y-X: richsu@hku.hk | - |
dc.identifier.authority | Li, DTS=rp02551 | - |
dc.identifier.authority | Su, Y-X=rp01916 | - |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1016/j.ijom.2020.01.008 | - |
dc.identifier.scopus | eid_2-s2.0-85078164012 | - |
dc.identifier.hkuros | 309684 | - |
dc.identifier.volume | 49 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 1351 | - |
dc.identifier.epage | 1354 | - |
dc.identifier.isi | WOS:000581528600016 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0901-5027 | - |