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- Publisher Website: 10.1177/0218492312462041
- Scopus: eid_2-s2.0-84885065703
- PMID: 24570555
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Article: Post-infarction ventricular septal defect: surgical outcomes in the last decade
Title | Post-infarction ventricular septal defect: surgical outcomes in the last decade |
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Authors | |
Keywords | Anterior wall myocardial infarction cardiac surgical procedures coronary artery bypass myocardial infarction ventricular septal rupture |
Issue Date | 2013 |
Publisher | Sage Publications Ltd. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201946 |
Citation | Asian Cardiovascular & Thoracic Annals, 2013, v. 21 n. 5, p. 539-545 How to Cite? |
Abstract | Background:
Post-infarction ventricular septal defects require surgical closure. Only a few studies have been conducted in Asian populations. This study reports the current outcomes and determinants affecting survival.
Methods:
Between January 1995 and January 2012, 40 patients underwent surgery for post-infarction ventricular septal defect. We analyzed demographics, clinical, angiographic, and echocardiographic parameters, operative data, postoperative morbidity, and survival. Mean follow-up was 5.2 ± 5.3 years. Univariate and multivariate analyses were used to determine the factors affecting 30-day mortality and long-term survival.
Results:
There was no intraoperative death. Our 30-day mortality was 20%. Single-vessel disease was found on coronary angiography in 63% of patients. Eight patients had concomitant coronary artery bypass grafting. Overall survival at 1, 5, and 10 years was 68%, 55%, and 42%, respectively. Event-free survival from subsequent angina, myocardial infarction, congestive heart failure, or percutaneous interventions at 1, 5, and 10 years was 66%, 43%, and 25%, respectively. Preoperative oliguria and postoperative sepsis were independent predictors of 30-days mortality on multivariate analysis (p = 0.02). Preoperative left ventricular function was associated with long-term survival (p = 0.048).
Conclusion:
We had good results of current postinfarction ventricular septal defect repair. Selected patients had concomitant coronary artery bypass grafting. Preoperative oliguria and postoperative sepsis were independent predictors of 30-day mortality, while left ventricular function was related to long-term survival. |
Persistent Identifier | http://hdl.handle.net/10722/283400 |
ISSN | 2022 Impact Factor: 0.7 2023 SCImago Journal Rankings: 0.241 |
DC Field | Value | Language |
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dc.contributor.author | Yam, N | - |
dc.contributor.author | Au, TWK | - |
dc.contributor.author | Cheng, LC | - |
dc.date.accessioned | 2020-06-22T02:55:56Z | - |
dc.date.available | 2020-06-22T02:55:56Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | Asian Cardiovascular & Thoracic Annals, 2013, v. 21 n. 5, p. 539-545 | - |
dc.identifier.issn | 0218-4923 | - |
dc.identifier.uri | http://hdl.handle.net/10722/283400 | - |
dc.description.abstract | Background: Post-infarction ventricular septal defects require surgical closure. Only a few studies have been conducted in Asian populations. This study reports the current outcomes and determinants affecting survival. Methods: Between January 1995 and January 2012, 40 patients underwent surgery for post-infarction ventricular septal defect. We analyzed demographics, clinical, angiographic, and echocardiographic parameters, operative data, postoperative morbidity, and survival. Mean follow-up was 5.2 ± 5.3 years. Univariate and multivariate analyses were used to determine the factors affecting 30-day mortality and long-term survival. Results: There was no intraoperative death. Our 30-day mortality was 20%. Single-vessel disease was found on coronary angiography in 63% of patients. Eight patients had concomitant coronary artery bypass grafting. Overall survival at 1, 5, and 10 years was 68%, 55%, and 42%, respectively. Event-free survival from subsequent angina, myocardial infarction, congestive heart failure, or percutaneous interventions at 1, 5, and 10 years was 66%, 43%, and 25%, respectively. Preoperative oliguria and postoperative sepsis were independent predictors of 30-days mortality on multivariate analysis (p = 0.02). Preoperative left ventricular function was associated with long-term survival (p = 0.048). Conclusion: We had good results of current postinfarction ventricular septal defect repair. Selected patients had concomitant coronary artery bypass grafting. Preoperative oliguria and postoperative sepsis were independent predictors of 30-day mortality, while left ventricular function was related to long-term survival. | - |
dc.language | eng | - |
dc.publisher | Sage Publications Ltd. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201946 | - |
dc.relation.ispartof | Asian Cardiovascular & Thoracic Annals | - |
dc.rights | Asian Cardiovascular & Thoracic Annals. Copyright © Sage Publications Ltd. | - |
dc.subject | Anterior wall myocardial infarction | - |
dc.subject | cardiac surgical procedures | - |
dc.subject | coronary artery bypass | - |
dc.subject | myocardial infarction | - |
dc.subject | ventricular septal rupture | - |
dc.title | Post-infarction ventricular septal defect: surgical outcomes in the last decade | - |
dc.type | Article | - |
dc.identifier.email | Au, TWK: auwkt@hkucc.hku.hk | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1177/0218492312462041 | - |
dc.identifier.pmid | 24570555 | - |
dc.identifier.scopus | eid_2-s2.0-84885065703 | - |
dc.identifier.hkuros | 310482 | - |
dc.identifier.volume | 21 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 539 | - |
dc.identifier.epage | 545 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0218-4923 | - |