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- Publisher Website: 10.1109/EMBC.2019.8856743
- Scopus: eid_2-s2.0-85077842727
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Conference Paper: Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics-Patient Specific Model
Title | Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics-Patient Specific Model |
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Authors | |
Keywords | Stress Biomedical optical imaging Surface morphology Optical fibers Surface reconstruction |
Issue Date | 2019 |
Publisher | Institute of Electrical and Electronics Engineers. The Journal's web site is located at https://ieeexplore.ieee.org/xpl/conhome.jsp?punumber=1000269 |
Citation | Proceedings of the 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Berlin, Germany, 23-27 July 2019, p. 5370-5373 How to Cite? |
Abstract | Glaucoma is associated with damage and death of optic nerve fibers within the Lamina Cribrosa (LC) region of the Optic Nerve Head. The pathogenesis of the disease is unclear, and the anterior LC surface morphology of different individuals can be one of the possible contributor of glaucoma development and progression. The current study evaluates the relationship between the LC surface curvature and distribution of shear stresses on the LC surface. The patient-specific reconstructed ocular model was developed and analyzed in a finite element analysis software. In addition, the effect of elastic modulus of both sclera and LC on the shear stress was examined. Results showed that there is a correlation between the shear stress distribution and the curvature of the anterior LC surface. This finding highlights the potential significance of the LC morphology on the distribution of LC shear stress and require further investigation. |
Persistent Identifier | http://hdl.handle.net/10722/285357 |
ISSN | 2020 SCImago Journal Rankings: 0.282 |
DC Field | Value | Language |
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dc.contributor.author | Satekenova, E | - |
dc.contributor.author | Ko, WLM | - |
dc.contributor.author | Kim, JR | - |
dc.date.accessioned | 2020-08-18T03:52:43Z | - |
dc.date.available | 2020-08-18T03:52:43Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Proceedings of the 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Berlin, Germany, 23-27 July 2019, p. 5370-5373 | - |
dc.identifier.issn | 1557-170X | - |
dc.identifier.uri | http://hdl.handle.net/10722/285357 | - |
dc.description.abstract | Glaucoma is associated with damage and death of optic nerve fibers within the Lamina Cribrosa (LC) region of the Optic Nerve Head. The pathogenesis of the disease is unclear, and the anterior LC surface morphology of different individuals can be one of the possible contributor of glaucoma development and progression. The current study evaluates the relationship between the LC surface curvature and distribution of shear stresses on the LC surface. The patient-specific reconstructed ocular model was developed and analyzed in a finite element analysis software. In addition, the effect of elastic modulus of both sclera and LC on the shear stress was examined. Results showed that there is a correlation between the shear stress distribution and the curvature of the anterior LC surface. This finding highlights the potential significance of the LC morphology on the distribution of LC shear stress and require further investigation. | - |
dc.language | eng | - |
dc.publisher | Institute of Electrical and Electronics Engineers. The Journal's web site is located at https://ieeexplore.ieee.org/xpl/conhome.jsp?punumber=1000269 | - |
dc.relation.ispartof | IEEE Engineering in Medicine and Biology Society (EMBC) Conference Proceedings | - |
dc.rights | IEEE Engineering in Medicine and Biology Society (EMBC) Conference Proceedings. Copyright © Institute of Electrical and Electronics Engineers. | - |
dc.rights | ©2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. | - |
dc.subject | Stress | - |
dc.subject | Biomedical optical imaging | - |
dc.subject | Surface morphology | - |
dc.subject | Optical fibers | - |
dc.subject | Surface reconstruction | - |
dc.title | Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics-Patient Specific Model | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Ko, WLM: matchko@hku.hk | - |
dc.identifier.doi | 10.1109/EMBC.2019.8856743 | - |
dc.identifier.scopus | eid_2-s2.0-85077842727 | - |
dc.identifier.hkuros | 312859 | - |
dc.identifier.spage | 5370 | - |
dc.identifier.epage | 5373 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1557-170X | - |