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Article: Antibiotic is a safe and feasible option for uncomplicated appendicitis in pregnancy ‐ a retrospective cohort study

TitleAntibiotic is a safe and feasible option for uncomplicated appendicitis in pregnancy ‐ a retrospective cohort study
Authors
Keywordsacute appendicitis
antibiotic therapy
pregnancy
Issue Date2020
PublisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1758-5910
Citation
Asian Journal of Endoscopic Surgery, 2020, Epub 2020-08-12 How to Cite?
AbstractIntroduction: Acute appendicitis is the commonest surgical emergency during pregnancy. The aim of this study is to evaluate the outcomes between antibiotic therapy and appendectomy in the management of uncomplicated appendicitis during gestation. Methods: From January 2015 to April 2019, there were 2174 emergency appendicitis diagnosed in the University of Hong Kong‐Shenzhen Hospital. Among them, 54 pregnant women were diagnosed with acute uncomplicated appendicitis and the clinical records were reviewed. Clinical demographics and outcomes including gestational age at delivery, mode of delivery, birth weight, APGAR score at 1 minute, fetal loss and overall length of stay were compared between the operation group and the antibiotic treatment group. Results: The baseline characteristics showed no statistically significant difference between the two groups (P > .05). In the appendectomy group (n = 20), one patient had wound infection while none of the patients in the antibiotic therapy group (n = 34) experienced any complication. In the antibiotic treatment group, appendicitis recurred in one patient during pregnancy and in two patients after deliveries, which were all treated with appendectomy. The mean hospital stay of the antibiotic treatment group was shorter than that of the appendectomy group, but there was no significant difference (4.94 ± 2.6 days vs 6.25 ± 3.5 days, P = .540). There was no difference in gestational age at delivery, mode of delivery, birth weight and APGAR scores between the two groups (P > .05). Conclusions: For acute uncomplicated appendicitis during pregnancy, antibiotics treatment is a safe and feasible option.
Persistent Identifierhttp://hdl.handle.net/10722/286347
ISSN
2023 Impact Factor: 0.9
2023 SCImago Journal Rankings: 0.390
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLiu, J-
dc.contributor.authorAhmad, M-
dc.contributor.authorWu, J-
dc.contributor.authorTong, XJ-
dc.contributor.authorZeng, HZ-
dc.contributor.authorChan, FSY-
dc.contributor.authorFan, JKM-
dc.date.accessioned2020-08-31T07:02:36Z-
dc.date.available2020-08-31T07:02:36Z-
dc.date.issued2020-
dc.identifier.citationAsian Journal of Endoscopic Surgery, 2020, Epub 2020-08-12-
dc.identifier.issn1758-5910-
dc.identifier.urihttp://hdl.handle.net/10722/286347-
dc.description.abstractIntroduction: Acute appendicitis is the commonest surgical emergency during pregnancy. The aim of this study is to evaluate the outcomes between antibiotic therapy and appendectomy in the management of uncomplicated appendicitis during gestation. Methods: From January 2015 to April 2019, there were 2174 emergency appendicitis diagnosed in the University of Hong Kong‐Shenzhen Hospital. Among them, 54 pregnant women were diagnosed with acute uncomplicated appendicitis and the clinical records were reviewed. Clinical demographics and outcomes including gestational age at delivery, mode of delivery, birth weight, APGAR score at 1 minute, fetal loss and overall length of stay were compared between the operation group and the antibiotic treatment group. Results: The baseline characteristics showed no statistically significant difference between the two groups (P > .05). In the appendectomy group (n = 20), one patient had wound infection while none of the patients in the antibiotic therapy group (n = 34) experienced any complication. In the antibiotic treatment group, appendicitis recurred in one patient during pregnancy and in two patients after deliveries, which were all treated with appendectomy. The mean hospital stay of the antibiotic treatment group was shorter than that of the appendectomy group, but there was no significant difference (4.94 ± 2.6 days vs 6.25 ± 3.5 days, P = .540). There was no difference in gestational age at delivery, mode of delivery, birth weight and APGAR scores between the two groups (P > .05). Conclusions: For acute uncomplicated appendicitis during pregnancy, antibiotics treatment is a safe and feasible option.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1758-5910-
dc.relation.ispartofAsian Journal of Endoscopic Surgery-
dc.rightsPreprint This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Postprint This is the peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.-
dc.subjectacute appendicitis-
dc.subjectantibiotic therapy-
dc.subjectpregnancy-
dc.titleAntibiotic is a safe and feasible option for uncomplicated appendicitis in pregnancy ‐ a retrospective cohort study-
dc.typeArticle-
dc.identifier.emailChan, FSY: fsychan@hku.hk-
dc.identifier.emailFan, JKM: drjoefan@hku.hk-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/ases.12851-
dc.identifier.pmid32789955-
dc.identifier.scopuseid_2-s2.0-85103802067-
dc.identifier.hkuros313060-
dc.identifier.volumeEpub 2020-08-12-
dc.identifier.isiWOS:000558579200001-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl1758-5902-

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