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Article: Prevention of demineralization around orthodontic brackets using sealants: a systematic review and meta-analysis

TitlePrevention of demineralization around orthodontic brackets using sealants: a systematic review and meta-analysis
Authors
KeywordsDental caries
Fluorides
Orthodontics
Resins
Systematic review
Tooth demineralization
Issue Date2019
PublisherAmerican Academy of Pediatric Dentistry. The Journal's web site is located at http://www.aapd.org/publications/peddent/
Citation
Pediatric Dentistry, 2019, v. 41 n. 6, p. 430-531 How to Cite?
AbstractPurpose: To evaluate the role of sealants in the prevention of enamel white spot lesions (EWSLs) around bonded orthodontic brackets. Methods: Eight databases and grey literature were searched for randomized or quasirandomized controlled clinical trials that assessed the placement of sealants around bonded brackets for the prevention of demineralization during fixed orthodontic treatment. Two reviewers independently selected studies, extracted data, assessed the risk of bias using Cochrane Risk of bias tool 2.0, and evaluated the certainty of evidence using the GRADE approach. Results: Eight clinical trials were included for qualitative synthesis; five of which assessed the outcome at debonding and hence were included for quantitative synthesis. Odds ratios (ORs) were calculated using the corrected Becker-Balagtas method. The OR of EWSLs in the sealants group versus the control group was found to be 0.69 (95 percent confidence interval [95% CI] equals 0.53, 0.89; P=.005) in the five included studies; however, after performing sensitivity analysis by excluding two studies with high risk of bias, the value was 0.68 (95% CI equals 0.41, 1.13; P=0.138). Conclusions: The certainty of evidence regarding the effectiveness of sealants in the prevention of the EWSLs was found to be moderate (downgraded because of the study limitations).
Persistent Identifierhttp://hdl.handle.net/10722/287258
ISSN
2023 Impact Factor: 1.5
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSardana, D-
dc.contributor.authorManchanda, S-
dc.contributor.authorEkambaram, M-
dc.contributor.authorYang, Y-
dc.contributor.authorMcGrath, CP-
dc.contributor.authorYiu, CKY-
dc.date.accessioned2020-09-22T02:58:15Z-
dc.date.available2020-09-22T02:58:15Z-
dc.date.issued2019-
dc.identifier.citationPediatric Dentistry, 2019, v. 41 n. 6, p. 430-531-
dc.identifier.issn0164-1263-
dc.identifier.urihttp://hdl.handle.net/10722/287258-
dc.description.abstractPurpose: To evaluate the role of sealants in the prevention of enamel white spot lesions (EWSLs) around bonded orthodontic brackets. Methods: Eight databases and grey literature were searched for randomized or quasirandomized controlled clinical trials that assessed the placement of sealants around bonded brackets for the prevention of demineralization during fixed orthodontic treatment. Two reviewers independently selected studies, extracted data, assessed the risk of bias using Cochrane Risk of bias tool 2.0, and evaluated the certainty of evidence using the GRADE approach. Results: Eight clinical trials were included for qualitative synthesis; five of which assessed the outcome at debonding and hence were included for quantitative synthesis. Odds ratios (ORs) were calculated using the corrected Becker-Balagtas method. The OR of EWSLs in the sealants group versus the control group was found to be 0.69 (95 percent confidence interval [95% CI] equals 0.53, 0.89; P=.005) in the five included studies; however, after performing sensitivity analysis by excluding two studies with high risk of bias, the value was 0.68 (95% CI equals 0.41, 1.13; P=0.138). Conclusions: The certainty of evidence regarding the effectiveness of sealants in the prevention of the EWSLs was found to be moderate (downgraded because of the study limitations).-
dc.languageeng-
dc.publisherAmerican Academy of Pediatric Dentistry. The Journal's web site is located at http://www.aapd.org/publications/peddent/-
dc.relation.ispartofPediatric Dentistry-
dc.subjectDental caries-
dc.subjectFluorides-
dc.subjectOrthodontics-
dc.subjectResins-
dc.subjectSystematic review-
dc.subjectTooth demineralization-
dc.titlePrevention of demineralization around orthodontic brackets using sealants: a systematic review and meta-analysis-
dc.typeArticle-
dc.identifier.emailEkambaram, M: drmani@hku.hk-
dc.identifier.emailYang, Y: yangyanq@hku.hk-
dc.identifier.emailMcGrath, CP: mcgrathc@hkucc.hku.hk-
dc.identifier.emailYiu, CKY: ckyyiu@hkucc.hku.hk-
dc.identifier.authorityEkambaram, M=rp02026-
dc.identifier.authorityYang, Y=rp00045-
dc.identifier.authorityMcGrath, CP=rp00037-
dc.identifier.authorityYiu, CKY=rp00018-
dc.identifier.pmid31882028-
dc.identifier.scopuseid_2-s2.0-85077251232-
dc.identifier.hkuros314435-
dc.identifier.volume41-
dc.identifier.issue6-
dc.identifier.spage430-
dc.identifier.epage531-
dc.identifier.isiWOS:000504819600004-
dc.publisher.placeUnited States-
dc.identifier.issnl0164-1263-

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