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Article: Anti-Müllerian Hormone in PCOS: A Review Informing International Guidelines

TitleAnti-Müllerian Hormone in PCOS: A Review Informing International Guidelines
Authors
Keywordspolycystic ovary syndrome
review
anti-Müllerian hormone
adolescent
adult
Issue Date2019
PublisherElsevier Ltd, Trends Journals. The Journal's web site is located at http://www.elsevier.com/locate/tem
Citation
Trends in Endocrinology and Metabolism, 2019, v. 30 n. 7, p. 467-478 How to Cite?
AbstractPolycystic ovary syndrome (PCOS) affects 8–13% of women. The Rotterdam diagnostic criteria include polycystic ovarian morphology (PCOM) on ultrasound, but given recognized challenges, serum anti-Müllerian hormone (AMH) is proposed as an alternative. To inform international PCOS guidelines, a systematic review was completed. Key identified gaps include large international studies in well-defined populations across the lifespan, clustering of AMH with PCOS features, relationships to long-term health outcomes, and improved quality, assay standardization, and sample handling, all needed to determine cut offs. Here we identify research priorities to address these gaps and enhance AMH utility in PCOS. Once issues are addressed, AMH levels could replace more costly and less accessible ultrasound in PCOS diagnosis. © 2019
Persistent Identifierhttp://hdl.handle.net/10722/287756
ISSN
2023 Impact Factor: 11.4
2023 SCImago Journal Rankings: 2.927
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTeede, H-
dc.contributor.authorMisso, M-
dc.contributor.authorTassone, EC-
dc.contributor.authorDewailly, D-
dc.contributor.authorNg, EH-
dc.contributor.authorAzziz, R-
dc.contributor.authorNorman, RJ-
dc.contributor.authorAndersen, M-
dc.contributor.authorFranks, S-
dc.contributor.authorHoeger, K-
dc.contributor.authorHutchison, S-
dc.contributor.authorOberfield, S-
dc.contributor.authorShah, D-
dc.contributor.authorHohmann, F-
dc.contributor.authorOttey, S-
dc.contributor.authorDabadghao, P-
dc.contributor.authorLaven, JSE-
dc.date.accessioned2020-10-05T12:02:48Z-
dc.date.available2020-10-05T12:02:48Z-
dc.date.issued2019-
dc.identifier.citationTrends in Endocrinology and Metabolism, 2019, v. 30 n. 7, p. 467-478-
dc.identifier.issn1043-2760-
dc.identifier.urihttp://hdl.handle.net/10722/287756-
dc.description.abstractPolycystic ovary syndrome (PCOS) affects 8–13% of women. The Rotterdam diagnostic criteria include polycystic ovarian morphology (PCOM) on ultrasound, but given recognized challenges, serum anti-Müllerian hormone (AMH) is proposed as an alternative. To inform international PCOS guidelines, a systematic review was completed. Key identified gaps include large international studies in well-defined populations across the lifespan, clustering of AMH with PCOS features, relationships to long-term health outcomes, and improved quality, assay standardization, and sample handling, all needed to determine cut offs. Here we identify research priorities to address these gaps and enhance AMH utility in PCOS. Once issues are addressed, AMH levels could replace more costly and less accessible ultrasound in PCOS diagnosis. © 2019-
dc.languageeng-
dc.publisherElsevier Ltd, Trends Journals. The Journal's web site is located at http://www.elsevier.com/locate/tem-
dc.relation.ispartofTrends in Endocrinology and Metabolism-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectpolycystic ovary syndrome-
dc.subjectreview-
dc.subjectanti-Müllerian hormone-
dc.subjectadolescent-
dc.subjectadult-
dc.titleAnti-Müllerian Hormone in PCOS: A Review Informing International Guidelines-
dc.typeArticle-
dc.identifier.emailNg, EH: nghye@hku.hk-
dc.identifier.authorityNg, EH=rp00426-
dc.description.naturepostprint-
dc.identifier.doi10.1016/j.tem.2019.04.006-
dc.identifier.pmid31160167-
dc.identifier.scopuseid_2-s2.0-85066313394-
dc.identifier.hkuros314953-
dc.identifier.volume30-
dc.identifier.issue7-
dc.identifier.spage467-
dc.identifier.epage478-
dc.identifier.isiWOS:000471823500008-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl1043-2760-

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