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Article: Fetal diagnosis of KCNQ1‐variant long QT syndrome using fetal echocardiography and magnetocardiography

TitleFetal diagnosis of KCNQ1‐variant long QT syndrome using fetal echocardiography and magnetocardiography
Authors
Desai, LWakai, RTsao, STStrasburger, JGotteiner, NPatel, A
Keywordsfetal bradycardia
fetal echocardiography
fetal magnetocardiography
long QT syndrome
Issue Date2020
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1
Citation
Pacing and Clinical Electrophysiology, 2020, v. 43 n. 4, p. 430-433 How to Cite?
DOI: http://dx.doi.org/10.1111/pace.13900
AbstractA pregnant woman with KCNQ1 variant long QT syndrome (LQTS) underwent fetal magnetocardiography (fMCG) after atrioventricular (AV) block was noted during fetal echocardiogram—atypical for LQTS type 1. Concern for fetal LQTS on fMCG prompted monitoring of maternal labs, change of maternal beta blocker therapy, and frequent fetal echocardiograms. Collaboration between obstetricians, neonatologists, and pediatric cardiologists ensured safe delivery. Beta blocker therapy was initiated after birth, and postnatal evaluation confirmed genotype and phenotype positive LQTS in the infant. Our experience suggests diagnosis and evaluation of fetal LQTS can alter antenatal management to reduce risk of poor fetal and postnatal outcomes.
Persistent Identifierhttp://hdl.handle.net/10722/287964
ISSN
0147-8389
2021 Impact Factor: 1.912
2020 SCImago Journal Rankings: 0.686
PubMed Central ID
PMC7166171
ISI Accession Number ID
WOS:000524294700001

 

DC FieldValueLanguage
dc.contributor.authorDesai, L-
dc.contributor.authorWakai, R-
dc.contributor.authorTsao, ST-
dc.contributor.authorStrasburger, J-
dc.contributor.authorGotteiner, N-
dc.contributor.authorPatel, A-
dc.date.accessioned2020-10-05T12:05:50Z-
dc.date.available2020-10-05T12:05:50Z-
dc.date.issued2020-
dc.identifier.citationPacing and Clinical Electrophysiology, 2020, v. 43 n. 4, p. 430-433-
dc.identifier.issn0147-8389-
dc.identifier.urihttp://hdl.handle.net/10722/287964-
dc.description.abstractA pregnant woman with KCNQ1 variant long QT syndrome (LQTS) underwent fetal magnetocardiography (fMCG) after atrioventricular (AV) block was noted during fetal echocardiogram—atypical for LQTS type 1. Concern for fetal LQTS on fMCG prompted monitoring of maternal labs, change of maternal beta blocker therapy, and frequent fetal echocardiograms. Collaboration between obstetricians, neonatologists, and pediatric cardiologists ensured safe delivery. Beta blocker therapy was initiated after birth, and postnatal evaluation confirmed genotype and phenotype positive LQTS in the infant. Our experience suggests diagnosis and evaluation of fetal LQTS can alter antenatal management to reduce risk of poor fetal and postnatal outcomes.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1-
dc.relation.ispartofPacing and Clinical Electrophysiology-
dc.rightsPreprint This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Postprint This is the peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.-
dc.subjectfetal bradycardia-
dc.subjectfetal echocardiography-
dc.subjectfetal magnetocardiography-
dc.subjectlong QT syndrome-
dc.titleFetal diagnosis of KCNQ1‐variant long QT syndrome using fetal echocardiography and magnetocardiography-
dc.typeArticle-
dc.identifier.emailTsao, ST: stsao@hku.hk-
dc.identifier.authorityTsao, ST=rp02530-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/pace.13900-
dc.identifier.pmid32168391-
dc.identifier.pmcidPMC7166171-
dc.identifier.scopuseid_2-s2.0-85082933653-
dc.identifier.hkuros315519-
dc.identifier.volume43-
dc.identifier.issue4-
dc.identifier.spage430-
dc.identifier.epage433-
dc.identifier.isiWOS:000524294700001-
dc.publisher.placeUnited States-
dc.identifier.issnl0147-8389-

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