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Article: HLA-DQB1, -DQA1, -DPB1, and -DPA1 genotyping and haplotype frequencies for a Hong Kong Chinese population of 1064 individuals

TitleHLA-DQB1, -DQA1, -DPB1, and -DPA1 genotyping and haplotype frequencies for a Hong Kong Chinese population of 1064 individuals
Authors
Keywordsallele
frequency
gene frequency
gene locus
genetic algorithm
Issue Date2020
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/humimm
Citation
Human Immunology, 2020, v. 81 n. 1, p. 3-5 How to Cite?
AbstractHLA-DQB1, -DQA1, -DPB1, and -DPA1 genotyping and haplotype frequencies have been calculated from 1064 southern Chinese unrelated donors in a Hong Kong Bone Marrow Donor Registry. This is the first paper to report the distribution of DQB1-DQA1 and DPB1-DPA1 alleles in Hong Kong Chinese. Due to the Hardy-Weinberg equilibrium proportions (HWEP) deviation in DPB1 loci, this information may be of limited use for phylogenetic, comparative studies but will be useful for the permissible matching in HLA-DPB1 for Chinese patients awaiting haematopoietic stem cell transplantation in the near future due to the new recommendation of NMDP matching guidelines. The allele and haplotype data are available in the Allele Frequencies Net Database under the population name ''Hong Kong Chinese HKBMDR, DQ and DP'' and the identifier (AFND3667).
Persistent Identifierhttp://hdl.handle.net/10722/289149
ISSN
2023 Impact Factor: 3.1
2023 SCImago Journal Rankings: 0.781
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKwok, J-
dc.contributor.authorTang, WH-
dc.contributor.authorChu, WK-
dc.contributor.authorLIU, Z-
dc.contributor.authorYang, W-
dc.contributor.authorLee, CK-
dc.contributor.authorMiddleton, D-
dc.date.accessioned2020-10-22T08:08:30Z-
dc.date.available2020-10-22T08:08:30Z-
dc.date.issued2020-
dc.identifier.citationHuman Immunology, 2020, v. 81 n. 1, p. 3-5-
dc.identifier.issn0198-8859-
dc.identifier.urihttp://hdl.handle.net/10722/289149-
dc.description.abstractHLA-DQB1, -DQA1, -DPB1, and -DPA1 genotyping and haplotype frequencies have been calculated from 1064 southern Chinese unrelated donors in a Hong Kong Bone Marrow Donor Registry. This is the first paper to report the distribution of DQB1-DQA1 and DPB1-DPA1 alleles in Hong Kong Chinese. Due to the Hardy-Weinberg equilibrium proportions (HWEP) deviation in DPB1 loci, this information may be of limited use for phylogenetic, comparative studies but will be useful for the permissible matching in HLA-DPB1 for Chinese patients awaiting haematopoietic stem cell transplantation in the near future due to the new recommendation of NMDP matching guidelines. The allele and haplotype data are available in the Allele Frequencies Net Database under the population name ''Hong Kong Chinese HKBMDR, DQ and DP'' and the identifier (AFND3667).-
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/humimm-
dc.relation.ispartofHuman Immunology-
dc.subjectallele-
dc.subjectfrequency-
dc.subjectgene frequency-
dc.subjectgene locus-
dc.subjectgenetic algorithm-
dc.titleHLA-DQB1, -DQA1, -DPB1, and -DPA1 genotyping and haplotype frequencies for a Hong Kong Chinese population of 1064 individuals-
dc.typeArticle-
dc.identifier.emailKwok, J: kwoksy@HKUCC-COM.hku.hk-
dc.identifier.emailYang, W: yangwl@hku.hk-
dc.identifier.authorityYang, W=rp00524-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.humimm.2019.11.005-
dc.identifier.pmid31733926-
dc.identifier.scopuseid_2-s2.0-85075378091-
dc.identifier.hkuros316123-
dc.identifier.volume81-
dc.identifier.issue1-
dc.identifier.spage3-
dc.identifier.epage5-
dc.identifier.isiWOS:000511233700002-
dc.publisher.placeUnited States-
dc.identifier.issnl0198-8859-

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