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Conference Paper: Angiogenesis following peripheral blood stem cell therapy: evidence from perfusion MRI of patients with ischemic stroke

TitleAngiogenesis following peripheral blood stem cell therapy: evidence from perfusion MRI of patients with ischemic stroke
Authors
Lin, CCWu, WCShyu, WCLiu, YJChang, HCCLuo, YCChen, DCLin, CWChung, HWLin, SZ
Issue Date2020
PublisherInternational Society for Magnetic Resonance in Medicine (ISMRM) .
Citation
Proceedings of the 28th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Virtual Conference, 8-14 August 2020 How to Cite?
AbstractDynamic susceptibility-contrast perfusion-weighted MRI was performed on 15 chronic stroke patients receiving intracerebral implantation of peripheral blood stem cells (PBSC) at baseline and 6 longitudinal stages after therapy to derive relative cerebral blood volume around the implanted graft relative to contralateral white matter (rCBV ratio), with 15 control patients receiving baseline MRI plus two follow-ups. Nine of the 15 patients (60%) in the PBSC group showed significantly increased rCBV ratio than the baselines (1.39±0.60 versus 1.07±0.44; p < 0.01) at one week after implantation only, preceding functional improvements starting at one month as assessed by NIH stroke scale.
DescriptionDigital Poster Session: Neurovascular - Neurovascular: Stroke Imaging Clinical - no. 1618
Persistent Identifierhttp://hdl.handle.net/10722/289397

 

DC FieldValueLanguage
dc.contributor.authorLin, CC-
dc.contributor.authorWu, WC-
dc.contributor.authorShyu, WC-
dc.contributor.authorLiu, YJ-
dc.contributor.authorChang, HCC-
dc.contributor.authorLuo, YC-
dc.contributor.authorChen, DC-
dc.contributor.authorLin, CW-
dc.contributor.authorChung, HW-
dc.contributor.authorLin, SZ-
dc.date.accessioned2020-10-22T08:12:05Z-
dc.date.available2020-10-22T08:12:05Z-
dc.date.issued2020-
dc.identifier.citationProceedings of the 28th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Virtual Conference, 8-14 August 2020-
dc.identifier.urihttp://hdl.handle.net/10722/289397-
dc.descriptionDigital Poster Session: Neurovascular - Neurovascular: Stroke Imaging Clinical - no. 1618-
dc.description.abstractDynamic susceptibility-contrast perfusion-weighted MRI was performed on 15 chronic stroke patients receiving intracerebral implantation of peripheral blood stem cells (PBSC) at baseline and 6 longitudinal stages after therapy to derive relative cerebral blood volume around the implanted graft relative to contralateral white matter (rCBV ratio), with 15 control patients receiving baseline MRI plus two follow-ups. Nine of the 15 patients (60%) in the PBSC group showed significantly increased rCBV ratio than the baselines (1.39±0.60 versus 1.07±0.44; p < 0.01) at one week after implantation only, preceding functional improvements starting at one month as assessed by NIH stroke scale.-
dc.languageeng-
dc.publisherInternational Society for Magnetic Resonance in Medicine (ISMRM) . -
dc.relation.ispartofInternational Society for Magnetic Resonance in Medicine (ISMRM) 28th Annual Meeting-
dc.titleAngiogenesis following peripheral blood stem cell therapy: evidence from perfusion MRI of patients with ischemic stroke-
dc.typeConference_Paper-
dc.identifier.emailChang, HCC: hcchang@hku.hk-
dc.identifier.authorityChang, HCC=rp02024-
dc.identifier.hkuros316920-

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