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Article: Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer

TitleReconstitution of an active surface T3/T-cell antigen receptor by DNA transfer
Authors
Ohashi, Pamela S.Mak, Tak W.Van Den Elsen, PeterYanagi, YusukeYoshikai, YasunobuCalman, Andrew F.Terhorst, CoxStobo, John D.Weiss, Arthur
Issue Date1985
Citation
Nature, 1985, v. 316, n. 6029, p. 606-609 How to Cite?
DOI: http://dx.doi.org/10.1038/316606a0
AbstractWe have introduced a full-length complementary DNA of the T-cell antigen receptor β-chain into a mutant human T-cell line that lacked a complete β-chain messenger RNA, had a diminished level of α-chain transcript and did not express surface T3- or antigen receptor. Expression of the transfected β-chain led to a normal level of α-chain transcript and a structurally and functionally active T3 T-cell antigen receptor complex on the cell surface. © 1985 Nature Publishing Group.
Persistent Identifierhttp://hdl.handle.net/10722/292296
ISSN
0028-0836
2021 Impact Factor: 69.504
2020 SCImago Journal Rankings: 15.993
ISI Accession Number ID
WOS:A1985ANX3500041

 

DC FieldValueLanguage
dc.contributor.authorOhashi, Pamela S.-
dc.contributor.authorMak, Tak W.-
dc.contributor.authorVan Den Elsen, Peter-
dc.contributor.authorYanagi, Yusuke-
dc.contributor.authorYoshikai, Yasunobu-
dc.contributor.authorCalman, Andrew F.-
dc.contributor.authorTerhorst, Cox-
dc.contributor.authorStobo, John D.-
dc.contributor.authorWeiss, Arthur-
dc.date.accessioned2020-11-17T14:56:10Z-
dc.date.available2020-11-17T14:56:10Z-
dc.date.issued1985-
dc.identifier.citationNature, 1985, v. 316, n. 6029, p. 606-609-
dc.identifier.issn0028-0836-
dc.identifier.urihttp://hdl.handle.net/10722/292296-
dc.description.abstractWe have introduced a full-length complementary DNA of the T-cell antigen receptor β-chain into a mutant human T-cell line that lacked a complete β-chain messenger RNA, had a diminished level of α-chain transcript and did not express surface T3- or antigen receptor. Expression of the transfected β-chain led to a normal level of α-chain transcript and a structurally and functionally active T3 T-cell antigen receptor complex on the cell surface. © 1985 Nature Publishing Group.-
dc.languageeng-
dc.relation.ispartofNature-
dc.titleReconstitution of an active surface T3/T-cell antigen receptor by DNA transfer-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/316606a0-
dc.identifier.pmid4033759-
dc.identifier.scopuseid_2-s2.0-0022384633-
dc.identifier.volume316-
dc.identifier.issue6029-
dc.identifier.spage606-
dc.identifier.epage609-
dc.identifier.isiWOS:A1985ANX3500041-
dc.identifier.issnl0028-0836-

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