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- Publisher Website: 10.1002/eji.1830180216
- Scopus: eid_2-s2.0-0023871124
- PMID: 2965024
- WOS: WOS:A1988M795400015
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Article: Sequence and organization of the human T cell δ chain gene
Title | Sequence and organization of the human T cell δ chain gene |
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Authors | |
Issue Date | 1988 |
Citation | European Journal of Immunology, 1988, v. 18, n. 2, p. 283-287 How to Cite? |
Abstract | A novel human T cell receptor (TcR) gene, located 85 kbp upstream to the Cα coding regions, was isolated using human genomic clones to identify cDNA homologous to messages encoded by this region. The deduced protein sequence of this gene is highly homologous to that of the newly identified constant region found in the murine TcR α chain locus. This gene undergoes rearrangements and is expressed at the RNA level in human thymocytes, peripheral T cells and several leukemic T cell lines which have been shown to express the surface γ‐δ heterodimer, suggesting that this gene encodes the human T cell δ chain. Copyright © 1988 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim |
Persistent Identifier | http://hdl.handle.net/10722/292336 |
ISSN | 2023 Impact Factor: 4.5 2023 SCImago Journal Rankings: 1.627 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Takihar, Yoshihiro | - |
dc.contributor.author | Champagne, Eric | - |
dc.contributor.author | Griesse, Henrik | - |
dc.contributor.author | Kimura, Nobuhiro | - |
dc.contributor.author | Tkachuk, Douglas | - |
dc.contributor.author | Reiman, Jörg | - |
dc.contributor.author | Okad, Ami | - |
dc.contributor.author | Alt, Frederick W. | - |
dc.contributor.author | Ches, Leonard | - |
dc.contributor.author | Minden, Mark | - |
dc.contributor.author | Mak, Tak W. | - |
dc.date.accessioned | 2020-11-17T14:56:15Z | - |
dc.date.available | 2020-11-17T14:56:15Z | - |
dc.date.issued | 1988 | - |
dc.identifier.citation | European Journal of Immunology, 1988, v. 18, n. 2, p. 283-287 | - |
dc.identifier.issn | 0014-2980 | - |
dc.identifier.uri | http://hdl.handle.net/10722/292336 | - |
dc.description.abstract | A novel human T cell receptor (TcR) gene, located 85 kbp upstream to the Cα coding regions, was isolated using human genomic clones to identify cDNA homologous to messages encoded by this region. The deduced protein sequence of this gene is highly homologous to that of the newly identified constant region found in the murine TcR α chain locus. This gene undergoes rearrangements and is expressed at the RNA level in human thymocytes, peripheral T cells and several leukemic T cell lines which have been shown to express the surface γ‐δ heterodimer, suggesting that this gene encodes the human T cell δ chain. Copyright © 1988 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim | - |
dc.language | eng | - |
dc.relation.ispartof | European Journal of Immunology | - |
dc.title | Sequence and organization of the human T cell δ chain gene | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1002/eji.1830180216 | - |
dc.identifier.pmid | 2965024 | - |
dc.identifier.scopus | eid_2-s2.0-0023871124 | - |
dc.identifier.volume | 18 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 283 | - |
dc.identifier.epage | 287 | - |
dc.identifier.eissn | 1521-4141 | - |
dc.identifier.isi | WOS:A1988M795400015 | - |
dc.identifier.issnl | 0014-2980 | - |