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Article: Dissociation between affective experience and motivated behaviour in schizophrenia patients and their unaffected first-degree relatives and schizotypal individuals

TitleDissociation between affective experience and motivated behaviour in schizophrenia patients and their unaffected first-degree relatives and schizotypal individuals
Authors
Keywordsschizophrenia
Anhedonia
avolition
emotion-behaviour decoupling
unaffected relatives
schizotypy
Issue Date2018
Citation
Psychological Medicine, 2018, v. 48, n. 9, p. 1474-1483 How to Cite?
Abstract© 2017 Cambridge University Press. Background The neuropsychological origins of negative syndrome of schizophrenia remain elusive. Evidence from behavioural studies, which utilised emotion-inducing pictures to elicit motivated behaviour generally reported that that schizophrenia patients experienced similar affective experience as healthy individuals but failed to translate emotional salience to motivated behaviour, a phenomenon called emotion-behaviour decoupling. However, a few studies have examined emotion-behaviour decoupling in non-psychotic high-risk populations, who are relatively unaffected by medication effects. Methods In this study, we examined the nature and extent of emotion-behaviour decoupling in in three independent samples (65 schizophrenia patients v. 63 controls; 40 unaffected relatives v. 45 controls; and 32 individuals with social anhedonia v. 32 controls). We administered an experimental task to examine their affective experience and its coupling with behaviour, using emotion-inducing slides, and allowed participants to alter stimulus exposure using button-pressing to seek pleasure or avoid aversion. Results Schizophrenia patients reported similar affective experiences as their controls, while their unaffected relatives and individuals with high levels of social anhedonia exhibited attenuated affective experiences, in particular in the arousal aspect. Compared with their respective control groups, all of the three groups showed emotion-behaviour decoupling. Conclusions Our findings support that both genetically and behaviourally high-risk groups exhibit emotion-behaviour decoupling. The familial association apparently supports its role as a putative trait marker for schizophrenia.
Persistent Identifierhttp://hdl.handle.net/10722/293047
ISSN
2023 Impact Factor: 5.9
2023 SCImago Journal Rankings: 2.768
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorXie, Dong Jie-
dc.contributor.authorLui, Simon S.Y.-
dc.contributor.authorGeng, Fu Lei-
dc.contributor.authorYang, Zhuo Ya-
dc.contributor.authorZou, Ying Min-
dc.contributor.authorLi, Ying-
dc.contributor.authorYeung, Hera K.H.-
dc.contributor.authorCheung, Eric F.C.-
dc.contributor.authorHeerey, Erin A.-
dc.contributor.authorChan, Raymond C.K.-
dc.date.accessioned2020-11-17T14:57:45Z-
dc.date.available2020-11-17T14:57:45Z-
dc.date.issued2018-
dc.identifier.citationPsychological Medicine, 2018, v. 48, n. 9, p. 1474-1483-
dc.identifier.issn0033-2917-
dc.identifier.urihttp://hdl.handle.net/10722/293047-
dc.description.abstract© 2017 Cambridge University Press. Background The neuropsychological origins of negative syndrome of schizophrenia remain elusive. Evidence from behavioural studies, which utilised emotion-inducing pictures to elicit motivated behaviour generally reported that that schizophrenia patients experienced similar affective experience as healthy individuals but failed to translate emotional salience to motivated behaviour, a phenomenon called emotion-behaviour decoupling. However, a few studies have examined emotion-behaviour decoupling in non-psychotic high-risk populations, who are relatively unaffected by medication effects. Methods In this study, we examined the nature and extent of emotion-behaviour decoupling in in three independent samples (65 schizophrenia patients v. 63 controls; 40 unaffected relatives v. 45 controls; and 32 individuals with social anhedonia v. 32 controls). We administered an experimental task to examine their affective experience and its coupling with behaviour, using emotion-inducing slides, and allowed participants to alter stimulus exposure using button-pressing to seek pleasure or avoid aversion. Results Schizophrenia patients reported similar affective experiences as their controls, while their unaffected relatives and individuals with high levels of social anhedonia exhibited attenuated affective experiences, in particular in the arousal aspect. Compared with their respective control groups, all of the three groups showed emotion-behaviour decoupling. Conclusions Our findings support that both genetically and behaviourally high-risk groups exhibit emotion-behaviour decoupling. The familial association apparently supports its role as a putative trait marker for schizophrenia.-
dc.languageeng-
dc.relation.ispartofPsychological Medicine-
dc.subjectschizophrenia-
dc.subjectAnhedonia-
dc.subjectavolition-
dc.subjectemotion-behaviour decoupling-
dc.subjectunaffected relatives-
dc.subjectschizotypy-
dc.titleDissociation between affective experience and motivated behaviour in schizophrenia patients and their unaffected first-degree relatives and schizotypal individuals-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1017/S0033291717002926-
dc.identifier.pmid29017618-
dc.identifier.scopuseid_2-s2.0-85031493831-
dc.identifier.hkuros320161-
dc.identifier.volume48-
dc.identifier.issue9-
dc.identifier.spage1474-
dc.identifier.epage1483-
dc.identifier.eissn1469-8978-
dc.identifier.isiWOS:000435649900009-
dc.identifier.issnl0033-2917-

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