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Article: Resource, chemical structure and activity of natural polysaccharides against alcoholic liver damages

TitleResource, chemical structure and activity of natural polysaccharides against alcoholic liver damages
Authors
KeywordsAlcoholic liver diseases
Polysaccharide
Hepatoprotection
Structural elucidation
Structure-activity relationship
Issue Date2020
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/carbpol
Citation
Carbohydrate Polymers, 2020, v. 241, p. article no. 116355 How to Cite?
AbstractMany natural polysaccharides from bio-resources hold advantages of multi-functions, high efficiency, non-toxicity or low side effect, and have strong potentials in protection against alcoholic liver damages. This review summarized the bio-resources, chemical and structural characteristics of natural polysaccharides with potentials in inhibition against alcoholic liver damages, and also emphasized knowledge on correlations between their chemical structure and function. Approximately 95 species were confirmed in generation of hepatoprotective polysaccharides. Products as crude polysaccharides originated from 17 species were sum up despite the indetermination of their accurate structure. Additional four polysaccharides were described for their known chemical structures. Possible roles of hepatoprotective polysaccharides were provided with evidence on antioxidant promotion, lipids regulation, apoptosis inhibition and anti-inflammation, as well as confirmations in immune enhancement, iron removal and anti-fibrosis when currently treated against the alcoholic liver damages. To sum up, this overview could serve to guide development and utilization of natural hepatoprotective polysaccharides.
Persistent Identifierhttp://hdl.handle.net/10722/293647
ISSN
2023 Impact Factor: 10.7
2023 SCImago Journal Rankings: 1.831
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYang, Y-
dc.contributor.authorJi, J-
dc.contributor.authorDi, L-
dc.contributor.authorLi, J-
dc.contributor.authorHu, L-
dc.contributor.authorQiao, H-
dc.contributor.authorWang, L-
dc.contributor.authorFeng, Y-
dc.date.accessioned2020-11-23T08:19:47Z-
dc.date.available2020-11-23T08:19:47Z-
dc.date.issued2020-
dc.identifier.citationCarbohydrate Polymers, 2020, v. 241, p. article no. 116355-
dc.identifier.issn0144-8617-
dc.identifier.urihttp://hdl.handle.net/10722/293647-
dc.description.abstractMany natural polysaccharides from bio-resources hold advantages of multi-functions, high efficiency, non-toxicity or low side effect, and have strong potentials in protection against alcoholic liver damages. This review summarized the bio-resources, chemical and structural characteristics of natural polysaccharides with potentials in inhibition against alcoholic liver damages, and also emphasized knowledge on correlations between their chemical structure and function. Approximately 95 species were confirmed in generation of hepatoprotective polysaccharides. Products as crude polysaccharides originated from 17 species were sum up despite the indetermination of their accurate structure. Additional four polysaccharides were described for their known chemical structures. Possible roles of hepatoprotective polysaccharides were provided with evidence on antioxidant promotion, lipids regulation, apoptosis inhibition and anti-inflammation, as well as confirmations in immune enhancement, iron removal and anti-fibrosis when currently treated against the alcoholic liver damages. To sum up, this overview could serve to guide development and utilization of natural hepatoprotective polysaccharides.-
dc.languageeng-
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/carbpol-
dc.relation.ispartofCarbohydrate Polymers-
dc.subjectAlcoholic liver diseases-
dc.subjectPolysaccharide-
dc.subjectHepatoprotection-
dc.subjectStructural elucidation-
dc.subjectStructure-activity relationship-
dc.titleResource, chemical structure and activity of natural polysaccharides against alcoholic liver damages-
dc.typeArticle-
dc.identifier.emailFeng, Y: yfeng@hku.hk-
dc.identifier.authorityFeng, Y=rp00466-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.carbpol.2020.116355-
dc.identifier.pmid32507196-
dc.identifier.scopuseid_2-s2.0-85084377591-
dc.identifier.hkuros320016-
dc.identifier.volume241-
dc.identifier.spagearticle no. 116355-
dc.identifier.epagearticle no. 116355-
dc.identifier.isiWOS:000539100600052-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl0144-8617-

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