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Article: Routine Pre- and Post-Hematopoietic Stem Cell Transplant Computed Tomography of the Abdomen for Detecting Invasive Fungal Infection Has Limited Value

TitleRoutine Pre- and Post-Hematopoietic Stem Cell Transplant Computed Tomography of the Abdomen for Detecting Invasive Fungal Infection Has Limited Value
Authors
KeywordsAllogeneic
Abdominal
Computed tomography
Stem cell transplantation
Issue Date2015
Citation
Biology of Blood and Marrow Transplantation, 2015, v. 21, n. 6, p. 1132-1135 How to Cite?
Abstract© 2015 American Society for Blood and Marrow Transplantation. The diagnostic utility of obtaining chest and abdomen computed tomography (CT) to evaluate for invasive fungal infection (IFI) before and after hematopoietic stem cell transplant (HSCT) remains unclear. The study was conducted as a quality improvement project. Chest and abdomen CT of patients who underwent an allogeneic HSCT over a 13-month period were reviewed. Scans included those performed pretransplant in all patients and days 0 to 100 post-transplant in selected patients. Sixty-six patients had chest and abdomen CT scans pretransplant. Chest CT was suggestive of IFI in 9 patients (13.6%), including 3 patients with prior history of IFI. After transplant, 37 patients had an initial chest CT and 14 patients an initial abdominal CT. The first chest CT post-transplant was suggestive of IFI in 3 patients; all had an abnormal CT pretransplant. After the initial post-transplant evaluation, 15 patients had 28 additional CT scans of the chest and 12 patients 19 additional CT scans of the abdomen. An abnormal chest CT with proven evidence of IFI was seen in only 1 patient. None of the 99 abdominal CT scans performed pre- or post-transplant had evidence of IFI. There is little benefit in obtaining abdominal CT scans in HSCT patients for detecting IFI either pre- or post-transplant.
Persistent Identifierhttp://hdl.handle.net/10722/294509
ISSN
2020 Impact Factor: 5.742
2015 SCImago Journal Rankings: 2.094
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorKaste, Sue C.-
dc.contributor.authorKaufman, Robert A.-
dc.contributor.authorSunkara, Anusha-
dc.contributor.authorKang, Guolian-
dc.contributor.authorMorris, Cynthia-
dc.contributor.authorLeung, Wing-
dc.contributor.authorSrinivasan, Ashok-
dc.date.accessioned2020-12-03T08:22:54Z-
dc.date.available2020-12-03T08:22:54Z-
dc.date.issued2015-
dc.identifier.citationBiology of Blood and Marrow Transplantation, 2015, v. 21, n. 6, p. 1132-1135-
dc.identifier.issn1083-8791-
dc.identifier.urihttp://hdl.handle.net/10722/294509-
dc.description.abstract© 2015 American Society for Blood and Marrow Transplantation. The diagnostic utility of obtaining chest and abdomen computed tomography (CT) to evaluate for invasive fungal infection (IFI) before and after hematopoietic stem cell transplant (HSCT) remains unclear. The study was conducted as a quality improvement project. Chest and abdomen CT of patients who underwent an allogeneic HSCT over a 13-month period were reviewed. Scans included those performed pretransplant in all patients and days 0 to 100 post-transplant in selected patients. Sixty-six patients had chest and abdomen CT scans pretransplant. Chest CT was suggestive of IFI in 9 patients (13.6%), including 3 patients with prior history of IFI. After transplant, 37 patients had an initial chest CT and 14 patients an initial abdominal CT. The first chest CT post-transplant was suggestive of IFI in 3 patients; all had an abnormal CT pretransplant. After the initial post-transplant evaluation, 15 patients had 28 additional CT scans of the chest and 12 patients 19 additional CT scans of the abdomen. An abnormal chest CT with proven evidence of IFI was seen in only 1 patient. None of the 99 abdominal CT scans performed pre- or post-transplant had evidence of IFI. There is little benefit in obtaining abdominal CT scans in HSCT patients for detecting IFI either pre- or post-transplant.-
dc.languageeng-
dc.relation.ispartofBiology of Blood and Marrow Transplantation-
dc.subjectAllogeneic-
dc.subjectAbdominal-
dc.subjectComputed tomography-
dc.subjectStem cell transplantation-
dc.titleRoutine Pre- and Post-Hematopoietic Stem Cell Transplant Computed Tomography of the Abdomen for Detecting Invasive Fungal Infection Has Limited Value-
dc.typeArticle-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1016/j.bbmt.2015.02.023-
dc.identifier.pmid25748273-
dc.identifier.pmcidPMC4624397-
dc.identifier.scopuseid_2-s2.0-84947487201-
dc.identifier.volume21-
dc.identifier.issue6-
dc.identifier.spage1132-
dc.identifier.epage1135-
dc.identifier.eissn1523-6536-
dc.identifier.issnl1083-8791-

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