File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Increasing incidence of anaphylaxis in Hong Kong from 2009 to 2019—discrepancies of anaphylaxis care between adult and paediatric patients

TitleIncreasing incidence of anaphylaxis in Hong Kong from 2009 to 2019—discrepancies of anaphylaxis care between adult and paediatric patients
Authors
KeywordsAllergy
Anaphylaxis
Adrenaline autoinjector
Epidemiology
Incidence
Issue Date2020
PublisherWiley Open Access, published in association with European Academy of Allergy and Clinical Immunology. The Journal's web site is located at https://onlinelibrary.wiley.com/journal/20457022
Citation
Clinical and Translational Allergy, 2020, v. 10, p. article no. 51 How to Cite?
AbstractBackground: Anaphylaxis has been increasing in developed countries but there is very little published data on the burden of anaphylaxis and the pattern of adrenaline autoinjector (AAI) prescription from Asia. We aim to determine the incidence rates of anaphylaxis and prescription rates of AAI over the past decade in Hong Kong. Methods: Using a centralized electronic database of Hong Kong’s sole public-funded healthcare provider, we obtained and analysed all patients between 2009 and 2019 with physician-reported diagnosis of anaphylaxis. Incidence rates were calculated using population statistics as the denominator. Patients’ prescriptions on discharge were collected to determine the AAI prescription rates. Results: The overall 10-year estimated incidence rate of anaphylaxis was 3.57 per 100,000 person-years. An increasing trend over time across both paediatric and adult populations from 2009 to 2014 was found, which remained stable until 2019. This was more marked among the paediatric population (paediatric vs adult incidence rate ratio in 2019: 3.51 [95% CI 1.12–2.66] vs 1.82 [95% CI 1.05–1.60]). There was an overall increasing rate of AAI prescription for patients admitted for anaphylaxis, but the overall AAI prescription rate was less than 15% and was significantly less likely to be prescribed for the adult compared to paediatric patients (36.5% vs. 89.4%, p < 0.001). Conclusions: An increasing trend of anaphylaxis incidence rates over the past decade is evident in Asian populations, with a discrepantly low rate of AAI prescription, particularly in the adult patients.
Persistent Identifierhttp://hdl.handle.net/10722/294577
ISSN
2023 Impact Factor: 4.6
2023 SCImago Journal Rankings: 1.309
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLi, PH-
dc.contributor.authorLeung, ASY-
dc.contributor.authorLi, RMY-
dc.contributor.authorLeung, TF-
dc.contributor.authorLau, WCS-
dc.contributor.authorWong, GWK-
dc.date.accessioned2020-12-08T07:38:56Z-
dc.date.available2020-12-08T07:38:56Z-
dc.date.issued2020-
dc.identifier.citationClinical and Translational Allergy, 2020, v. 10, p. article no. 51-
dc.identifier.issn2045-7022-
dc.identifier.urihttp://hdl.handle.net/10722/294577-
dc.description.abstractBackground: Anaphylaxis has been increasing in developed countries but there is very little published data on the burden of anaphylaxis and the pattern of adrenaline autoinjector (AAI) prescription from Asia. We aim to determine the incidence rates of anaphylaxis and prescription rates of AAI over the past decade in Hong Kong. Methods: Using a centralized electronic database of Hong Kong’s sole public-funded healthcare provider, we obtained and analysed all patients between 2009 and 2019 with physician-reported diagnosis of anaphylaxis. Incidence rates were calculated using population statistics as the denominator. Patients’ prescriptions on discharge were collected to determine the AAI prescription rates. Results: The overall 10-year estimated incidence rate of anaphylaxis was 3.57 per 100,000 person-years. An increasing trend over time across both paediatric and adult populations from 2009 to 2014 was found, which remained stable until 2019. This was more marked among the paediatric population (paediatric vs adult incidence rate ratio in 2019: 3.51 [95% CI 1.12–2.66] vs 1.82 [95% CI 1.05–1.60]). There was an overall increasing rate of AAI prescription for patients admitted for anaphylaxis, but the overall AAI prescription rate was less than 15% and was significantly less likely to be prescribed for the adult compared to paediatric patients (36.5% vs. 89.4%, p < 0.001). Conclusions: An increasing trend of anaphylaxis incidence rates over the past decade is evident in Asian populations, with a discrepantly low rate of AAI prescription, particularly in the adult patients.-
dc.languageeng-
dc.publisherWiley Open Access, published in association with European Academy of Allergy and Clinical Immunology. The Journal's web site is located at https://onlinelibrary.wiley.com/journal/20457022-
dc.relation.ispartofClinical and Translational Allergy-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAllergy-
dc.subjectAnaphylaxis-
dc.subjectAdrenaline autoinjector-
dc.subjectEpidemiology-
dc.subjectIncidence-
dc.titleIncreasing incidence of anaphylaxis in Hong Kong from 2009 to 2019—discrepancies of anaphylaxis care between adult and paediatric patients-
dc.typeArticle-
dc.identifier.emailLi, PH: liphilip@hku.hk-
dc.identifier.emailLau, WCS: cslau@hku.hk-
dc.identifier.authorityLi, PH=rp02669-
dc.identifier.authorityLau, WCS=rp01348-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1186/s13601-020-00355-6-
dc.identifier.pmid33292497-
dc.identifier.pmcidPMC7677822-
dc.identifier.scopuseid_2-s2.0-85096188116-
dc.identifier.hkuros320576-
dc.identifier.volume10-
dc.identifier.spagearticle no. 51-
dc.identifier.epagearticle no. 51-
dc.identifier.isiWOS:000590494100001-
dc.publisher.placeUnited Kingdom-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats