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- Publisher Website: 10.1021/jacs.0c09664
- Scopus: eid_2-s2.0-85097892406
- PMID: 33211477
- WOS: WOS:000596904700002
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Article: Chemical Protein Synthesis: Advances, Challenges, and Outlooks
Title | Chemical Protein Synthesis: Advances, Challenges, and Outlooks |
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Authors | |
Issue Date | 2020 |
Publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html |
Citation | Journal of the American Chemical Society, 2020, v. 142 n. 48, p. 20288-20298 How to Cite? |
Abstract | Contemporary chemical protein synthesis has been dramatically advanced over the past few decades, which has enabled chemists to reach the landscape of synthetic biomacromolecules. Chemical synthesis can produce synthetic proteins with precisely controlled structures which are difficult or impossible to obtain via gene expression systems. Herein, we summarize the key enabling ligation technologies, major strategic developments, and some selected representative applications of synthetic proteins and provide an outlook for future development. |
Persistent Identifier | http://hdl.handle.net/10722/294586 |
ISSN | 2023 Impact Factor: 14.4 2023 SCImago Journal Rankings: 5.489 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | pTan, Y | - |
dc.contributor.author | WU, H | - |
dc.contributor.author | WEI, T | - |
dc.contributor.author | Li, X | - |
dc.date.accessioned | 2020-12-08T07:39:03Z | - |
dc.date.available | 2020-12-08T07:39:03Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Journal of the American Chemical Society, 2020, v. 142 n. 48, p. 20288-20298 | - |
dc.identifier.issn | 0002-7863 | - |
dc.identifier.uri | http://hdl.handle.net/10722/294586 | - |
dc.description.abstract | Contemporary chemical protein synthesis has been dramatically advanced over the past few decades, which has enabled chemists to reach the landscape of synthetic biomacromolecules. Chemical synthesis can produce synthetic proteins with precisely controlled structures which are difficult or impossible to obtain via gene expression systems. Herein, we summarize the key enabling ligation technologies, major strategic developments, and some selected representative applications of synthetic proteins and provide an outlook for future development. | - |
dc.language | eng | - |
dc.publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html | - |
dc.relation.ispartof | Journal of the American Chemical Society | - |
dc.rights | This document is the Accepted Manuscript version of a Published Work that appeared in final form in [JournalTitle], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [insert ACS Articles on Request author-directed link to Published Work, see http://pubs.acs.org/page/policy/articlesonrequest/index.html]. | - |
dc.title | Chemical Protein Synthesis: Advances, Challenges, and Outlooks | - |
dc.type | Article | - |
dc.identifier.email | pTan, Y: tanyi@hku.hk | - |
dc.identifier.email | Li, X: xuechenl@hku.hk | - |
dc.identifier.authority | Li, X=rp00742 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1021/jacs.0c09664 | - |
dc.identifier.pmid | 33211477 | - |
dc.identifier.scopus | eid_2-s2.0-85097892406 | - |
dc.identifier.hkuros | 320346 | - |
dc.identifier.volume | 142 | - |
dc.identifier.issue | 48 | - |
dc.identifier.spage | 20288 | - |
dc.identifier.epage | 20298 | - |
dc.identifier.isi | WOS:000596904700002 | - |
dc.publisher.place | United States | - |