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Article: Chinese Herbal Medicine for Reducing Chemotherapy-Associated Side-Effects in Breast Cancer Patients: A Systematic Review and Meta-Analysis

TitleChinese Herbal Medicine for Reducing Chemotherapy-Associated Side-Effects in Breast Cancer Patients: A Systematic Review and Meta-Analysis
Authors
Keywordsherbal medicine
chemotherapy
side effect
breast cancer
meta-analysis
Issue Date2020
PublisherFrontiers Research Foundation. The Journal's web site is located at http://www.frontiersin.org/oncology
Citation
Frontiers in Oncology, 2020, v. 10, article no. 599073 How to Cite?
AbstractBackground: Chemotherapy usually induces a variety of side-effects in cancer treatment as it cannot tell normal cells apart from cancer cells and kills both. Chinese herbal medicine (CHM) has been regarded as a potential effective intervention for relieving the side-effects of chemotherapy in breast cancer patients. Objective: This study aims to conduct a comprehensive systematic review and meta-analysis to evaluate the efficacy of CHM as adjuvant therapy for reducing the chemotherapy-induced side-effects in the treatment of breast cancer. Methods: Main electronic databases were searched up to May 2020 for Randomized Controlled Trials (RCTs) evaluating the effect of CHM on breast cancer patients with chemotherapy. The PRISMA statement was adopted in this study and meta-analyses were performed. Results: The included studies showed unsatisfied quality. Results based on available literature indicated that the adjunctive use of CHM with chemotherapy may reduce the chemotherapeutic agents-associated adverse events, including nausea and vomiting, diarrhea, alopecia, myelosuppression, and impaired immune function. Conclusion: A confident conclusion could not be have due to the lack of large scale and high quality trials.
Persistent Identifierhttp://hdl.handle.net/10722/295517
ISSN
2023 Impact Factor: 3.5
2023 SCImago Journal Rankings: 1.066
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLi, S-
dc.contributor.authorSo, TH-
dc.contributor.authorTang, G-
dc.contributor.authorTan, HY-
dc.contributor.authorWang, N-
dc.contributor.authorNg, BFL-
dc.contributor.authorChan, CKW-
dc.contributor.authorYu, ECL-
dc.contributor.authorFeng, Y-
dc.date.accessioned2021-01-25T11:16:00Z-
dc.date.available2021-01-25T11:16:00Z-
dc.date.issued2020-
dc.identifier.citationFrontiers in Oncology, 2020, v. 10, article no. 599073-
dc.identifier.issn2234-943X-
dc.identifier.urihttp://hdl.handle.net/10722/295517-
dc.description.abstractBackground: Chemotherapy usually induces a variety of side-effects in cancer treatment as it cannot tell normal cells apart from cancer cells and kills both. Chinese herbal medicine (CHM) has been regarded as a potential effective intervention for relieving the side-effects of chemotherapy in breast cancer patients. Objective: This study aims to conduct a comprehensive systematic review and meta-analysis to evaluate the efficacy of CHM as adjuvant therapy for reducing the chemotherapy-induced side-effects in the treatment of breast cancer. Methods: Main electronic databases were searched up to May 2020 for Randomized Controlled Trials (RCTs) evaluating the effect of CHM on breast cancer patients with chemotherapy. The PRISMA statement was adopted in this study and meta-analyses were performed. Results: The included studies showed unsatisfied quality. Results based on available literature indicated that the adjunctive use of CHM with chemotherapy may reduce the chemotherapeutic agents-associated adverse events, including nausea and vomiting, diarrhea, alopecia, myelosuppression, and impaired immune function. Conclusion: A confident conclusion could not be have due to the lack of large scale and high quality trials.-
dc.languageeng-
dc.publisherFrontiers Research Foundation. The Journal's web site is located at http://www.frontiersin.org/oncology-
dc.relation.ispartofFrontiers in Oncology-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectherbal medicine-
dc.subjectchemotherapy-
dc.subjectside effect-
dc.subjectbreast cancer-
dc.subjectmeta-analysis-
dc.titleChinese Herbal Medicine for Reducing Chemotherapy-Associated Side-Effects in Breast Cancer Patients: A Systematic Review and Meta-Analysis-
dc.typeArticle-
dc.identifier.emailLi, S: lishaha@hku.hk-
dc.identifier.emailSo, TH: sth495@hku.hk-
dc.identifier.emailTan, HY: hyhtan@hku.hk-
dc.identifier.emailWang, N: ckwang@hku.hk-
dc.identifier.emailFeng, Y: yfeng@hku.hk-
dc.identifier.authoritySo, TH=rp01981-
dc.identifier.authorityWang, N=rp02075-
dc.identifier.authorityFeng, Y=rp00466-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3389/fonc.2020.599073-
dc.identifier.pmid33363030-
dc.identifier.pmcidPMC7756083-
dc.identifier.scopuseid_2-s2.0-85098149782-
dc.identifier.hkuros320949-
dc.identifier.hkuros326399-
dc.identifier.volume10-
dc.identifier.spagearticle no. 599073-
dc.identifier.epagearticle no. 599073-
dc.identifier.isiWOS:000600958900001-
dc.publisher.placeSwitzerland-

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