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- Publisher Website: 10.1111/j.1747-0285.2010.01050.x
- Scopus: eid_2-s2.0-79551710372
- PMID: 21306567
- WOS: WOS:000287146200005
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Article: Synthesis and Antiviral Evaluation of New N-acylhydrazones Containing Glycine Residue
Title | Synthesis and Antiviral Evaluation of New N-acylhydrazones Containing Glycine Residue |
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Authors | |
Keywords | HIV-1 capsid assembly Synthesis N-acylhydrazone derivatives Antiviral activity |
Issue Date | 2011 |
Citation | Chemical Biology and Drug Design, 2011, v. 77, n. 3, p. 189-198 How to Cite? |
Abstract | N-acylhydrazones containing glycine residue 3a-j and 8a-h were synthesized as HIV-1 capsid protein assembly inhibitors. The structures of the novel N-acylhydrazone derivatives were characterized using different spectroscopic methods. Antiviral activity demonstrated that compound 8c bearing 4-methylphenyl moiety was the most active with low cytotoxicity. © 2011 John Wiley & Sons A/S. |
Persistent Identifier | http://hdl.handle.net/10722/297306 |
ISSN | 2023 Impact Factor: 3.2 2023 SCImago Journal Rankings: 0.579 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Tian, Baohe | - |
dc.contributor.author | He, Meizi | - |
dc.contributor.author | Tan, Zhiwu | - |
dc.contributor.author | Tang, Shixing | - |
dc.contributor.author | Hewlett, Indira | - |
dc.contributor.author | Chen, Shuguang | - |
dc.contributor.author | Jin, Yinxue | - |
dc.contributor.author | Yang, Ming | - |
dc.date.accessioned | 2021-03-15T07:33:29Z | - |
dc.date.available | 2021-03-15T07:33:29Z | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | Chemical Biology and Drug Design, 2011, v. 77, n. 3, p. 189-198 | - |
dc.identifier.issn | 1747-0277 | - |
dc.identifier.uri | http://hdl.handle.net/10722/297306 | - |
dc.description.abstract | N-acylhydrazones containing glycine residue 3a-j and 8a-h were synthesized as HIV-1 capsid protein assembly inhibitors. The structures of the novel N-acylhydrazone derivatives were characterized using different spectroscopic methods. Antiviral activity demonstrated that compound 8c bearing 4-methylphenyl moiety was the most active with low cytotoxicity. © 2011 John Wiley & Sons A/S. | - |
dc.language | eng | - |
dc.relation.ispartof | Chemical Biology and Drug Design | - |
dc.subject | HIV-1 capsid assembly | - |
dc.subject | Synthesis | - |
dc.subject | N-acylhydrazone derivatives | - |
dc.subject | Antiviral activity | - |
dc.title | Synthesis and Antiviral Evaluation of New N-acylhydrazones Containing Glycine Residue | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1111/j.1747-0285.2010.01050.x | - |
dc.identifier.pmid | 21306567 | - |
dc.identifier.scopus | eid_2-s2.0-79551710372 | - |
dc.identifier.volume | 77 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 189 | - |
dc.identifier.epage | 198 | - |
dc.identifier.eissn | 1747-0285 | - |
dc.identifier.isi | WOS:000287146200005 | - |
dc.identifier.issnl | 1747-0277 | - |