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Article: Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors
Title | Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors |
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Authors | |
Issue Date | 2006 |
Citation | Applied Physics Letters, 2006, v. 89, n. 23, article no. 232104 How to Cite? |
Abstract | The authors study deoxyribonucleic acid (DNA) sensing characteristics of carbon nanotube network field-effect transistors (CNNFETs) by monitoring their electrical responses upon immobilization with a DNA probe, hybridization with DNA analytes, and intercalation with a N, N′ -bis(3-propylimidazole)-1,4, 5,8-naphthalene diimide modified with Os (2, 2′ -bipyridine)2 Cl+ pendants. The CNNFETs immobilized by single-stranded DNA molecules demonstrate the selective sensing of its complementary and single-base mismatched DNA (difference of ∼16% in reduction of normalized drain current Id). Subsequent intercalation demonstrates a further sensitivity enhancement (difference of ∼13% in Id reduction) due to specific binding between hybridized DNA and intercalators, corroborated by the x-ray photoelectron spectroscopy study. © 2006 American Institute of Physics. |
Persistent Identifier | http://hdl.handle.net/10722/297962 |
ISSN | 2023 Impact Factor: 3.5 2023 SCImago Journal Rankings: 0.976 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Gui, Ee Ling | - |
dc.contributor.author | Li, Lain Jong | - |
dc.contributor.author | Lee, P. S. | - |
dc.contributor.author | Lohani, Anup | - |
dc.contributor.author | Mhaisalkar, S. G. | - |
dc.contributor.author | Cao, Qing | - |
dc.contributor.author | Kang, Seong Jun | - |
dc.contributor.author | Rogers, John A. | - |
dc.contributor.author | Tansil, N. C. | - |
dc.contributor.author | Gao, Zhiqiang | - |
dc.date.accessioned | 2021-04-08T03:07:21Z | - |
dc.date.available | 2021-04-08T03:07:21Z | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Applied Physics Letters, 2006, v. 89, n. 23, article no. 232104 | - |
dc.identifier.issn | 0003-6951 | - |
dc.identifier.uri | http://hdl.handle.net/10722/297962 | - |
dc.description.abstract | The authors study deoxyribonucleic acid (DNA) sensing characteristics of carbon nanotube network field-effect transistors (CNNFETs) by monitoring their electrical responses upon immobilization with a DNA probe, hybridization with DNA analytes, and intercalation with a N, N′ -bis(3-propylimidazole)-1,4, 5,8-naphthalene diimide modified with Os (2, 2′ -bipyridine)2 Cl+ pendants. The CNNFETs immobilized by single-stranded DNA molecules demonstrate the selective sensing of its complementary and single-base mismatched DNA (difference of ∼16% in reduction of normalized drain current Id). Subsequent intercalation demonstrates a further sensitivity enhancement (difference of ∼13% in Id reduction) due to specific binding between hybridized DNA and intercalators, corroborated by the x-ray photoelectron spectroscopy study. © 2006 American Institute of Physics. | - |
dc.language | eng | - |
dc.relation.ispartof | Applied Physics Letters | - |
dc.title | Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1063/1.2399355 | - |
dc.identifier.scopus | eid_2-s2.0-33845384184 | - |
dc.identifier.volume | 89 | - |
dc.identifier.issue | 23 | - |
dc.identifier.spage | article no. 232104 | - |
dc.identifier.epage | article no. 232104 | - |
dc.identifier.isi | WOS:000242709200058 | - |
dc.identifier.issnl | 0003-6951 | - |