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Article: Theory of mind in schizotypy: A behavioral and event-related potential (ERP) study
Title | Theory of mind in schizotypy: A behavioral and event-related potential (ERP) study |
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Authors | |
Keywords | Brain activity Event-related potential Schizotypy Theory of mind |
Issue Date | 2021 |
Publisher | Elsevier: Open Access Journals. The Journal's web site is located at http://www.elsevier.com/journals/schizophrenia-research-cognition/2215-0013 |
Citation | Schizophrenia Research: Cognition, 2021, v. 23, p. article no. 100190 How to Cite? |
Abstract | Background:
Schizophrenia is known for their theory of mind (ToM) impairment. However, this impairment in schizotypy (schizotypal traits) lacks investigation.
Aims:
The present study investigated: (1) whether ToM ability was impaired in schizotypy; (2) whether the ERP amplitudes in nine brain regions of interest associated with ToM (e.g., frontal region) in schizotypy and healthy controls differed; and (3) whether the relationship between ToM performances and ERP amplitudes in schizotypy differed from that in healthy controls.
Method:
Forty eight adolescents and young adults (16 schizotypy) with the mean age of 18 years were tested. The Reading the Mind in the Eyes Test (RMET) was used to assess their ToM during which ERP amplitudes were recorded.
Results:
The schizotypy group showed significantly lower ERP amplitudes in all conditions of RMET in frontal, frontal-central, central, occipital and temporal regions when compared to those in healthy controls. Also, schizotypy's ERP amplitudes in the frontal, frontal-central, central, occipital, and temporal regions were different from those in the healthy individuals in responding to different types of ToM stimuli (positive, negative and neutral). In schizotypy group, reaction time responding to emotional stimuli was negatively related to ERP amplitudes in the frontal, central-parietal, parietal, occipital, and occipito-temporal regions during RMET while no significant correlations were found in healthy controls.
Conclusion:
The present findings inform us with the knowledge regarding the neural and behavioral abnormality of ToM in schizotypy, suggesting that brain activity can be an alternative to detect ToM impairment in schizotypy. |
Persistent Identifier | http://hdl.handle.net/10722/299743 |
ISSN | 2023 Impact Factor: 2.3 2023 SCImago Journal Rankings: 1.018 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Leung, C | - |
dc.contributor.author | Lei, KS | - |
dc.contributor.author | Wang, SM | - |
dc.contributor.author | Lam, BYH | - |
dc.date.accessioned | 2021-05-26T03:28:27Z | - |
dc.date.available | 2021-05-26T03:28:27Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Schizophrenia Research: Cognition, 2021, v. 23, p. article no. 100190 | - |
dc.identifier.issn | 2215-0013 | - |
dc.identifier.uri | http://hdl.handle.net/10722/299743 | - |
dc.description.abstract | Background: Schizophrenia is known for their theory of mind (ToM) impairment. However, this impairment in schizotypy (schizotypal traits) lacks investigation. Aims: The present study investigated: (1) whether ToM ability was impaired in schizotypy; (2) whether the ERP amplitudes in nine brain regions of interest associated with ToM (e.g., frontal region) in schizotypy and healthy controls differed; and (3) whether the relationship between ToM performances and ERP amplitudes in schizotypy differed from that in healthy controls. Method: Forty eight adolescents and young adults (16 schizotypy) with the mean age of 18 years were tested. The Reading the Mind in the Eyes Test (RMET) was used to assess their ToM during which ERP amplitudes were recorded. Results: The schizotypy group showed significantly lower ERP amplitudes in all conditions of RMET in frontal, frontal-central, central, occipital and temporal regions when compared to those in healthy controls. Also, schizotypy's ERP amplitudes in the frontal, frontal-central, central, occipital, and temporal regions were different from those in the healthy individuals in responding to different types of ToM stimuli (positive, negative and neutral). In schizotypy group, reaction time responding to emotional stimuli was negatively related to ERP amplitudes in the frontal, central-parietal, parietal, occipital, and occipito-temporal regions during RMET while no significant correlations were found in healthy controls. Conclusion: The present findings inform us with the knowledge regarding the neural and behavioral abnormality of ToM in schizotypy, suggesting that brain activity can be an alternative to detect ToM impairment in schizotypy. | - |
dc.language | eng | - |
dc.publisher | Elsevier: Open Access Journals. The Journal's web site is located at http://www.elsevier.com/journals/schizophrenia-research-cognition/2215-0013 | - |
dc.relation.ispartof | Schizophrenia Research: Cognition | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Brain activity | - |
dc.subject | Event-related potential | - |
dc.subject | Schizotypy | - |
dc.subject | Theory of mind | - |
dc.title | Theory of mind in schizotypy: A behavioral and event-related potential (ERP) study | - |
dc.type | Article | - |
dc.identifier.email | Lam, BYH: byinhlam@hku.hk | - |
dc.identifier.authority | Lam, BYH=rp02724 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1016/j.scog.2020.100190 | - |
dc.identifier.pmid | 33204651 | - |
dc.identifier.pmcid | PMC7648172 | - |
dc.identifier.scopus | eid_2-s2.0-85092186688 | - |
dc.identifier.hkuros | 322488 | - |
dc.identifier.volume | 23 | - |
dc.identifier.spage | article no. 100190 | - |
dc.identifier.epage | article no. 100190 | - |
dc.identifier.isi | WOS:000658476800001 | - |
dc.publisher.place | Netherlands | - |