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Conference Paper: The Mechanism of Spinal Cord Stimulation in Animal Model of Neuropathic Pain

TitleThe Mechanism of Spinal Cord Stimulation in Animal Model of Neuropathic Pain
Authors
Issue Date2020
PublisherSAGE Publications. The Journal's web site is located at http://mpx.sagepub.com/home/
Citation
The 8th Asian Pain Symposium (APS 2019), Songdo, Incheon, Republic of Korea, 5-7 December 2019. Abstracts in Molecular Pain, 2020, v. 16, p. 38 How to Cite?
AbstractSpinal cord stimulation (SCS) has been shown to be effective in the management of certain neuropathic pain conditions; however, the underlying mechanisms are incompletely understood. Our study showed that the endocannabinoid system, and in particular the CB1 R, plays a pivotal role in the long-lasting and incremental reversal of hyperalgesia induced by repetitive SCS in a peripheral neuropathic pain model. Our another study demonstrated that spinal progenitor cells can be activated by SCS via descending pathways to relieve spinal cord injury-induced neuropathic pain. Further research direction in SCS using neuropathic pain animal model will also be discussed.
Persistent Identifierhttp://hdl.handle.net/10722/300758
ISSN
2023 Impact Factor: 2.8
2023 SCImago Journal Rankings: 0.904

 

DC FieldValueLanguage
dc.contributor.authorCheung, CW-
dc.date.accessioned2021-06-21T07:34:28Z-
dc.date.available2021-06-21T07:34:28Z-
dc.date.issued2020-
dc.identifier.citationThe 8th Asian Pain Symposium (APS 2019), Songdo, Incheon, Republic of Korea, 5-7 December 2019. Abstracts in Molecular Pain, 2020, v. 16, p. 38-
dc.identifier.issn1744-8069-
dc.identifier.urihttp://hdl.handle.net/10722/300758-
dc.description.abstractSpinal cord stimulation (SCS) has been shown to be effective in the management of certain neuropathic pain conditions; however, the underlying mechanisms are incompletely understood. Our study showed that the endocannabinoid system, and in particular the CB1 R, plays a pivotal role in the long-lasting and incremental reversal of hyperalgesia induced by repetitive SCS in a peripheral neuropathic pain model. Our another study demonstrated that spinal progenitor cells can be activated by SCS via descending pathways to relieve spinal cord injury-induced neuropathic pain. Further research direction in SCS using neuropathic pain animal model will also be discussed.-
dc.languageeng-
dc.publisherSAGE Publications. The Journal's web site is located at http://mpx.sagepub.com/home/-
dc.relation.ispartofMolecular Pain-
dc.relation.ispartofThe 8th Asian Pain Symposium (APS 2019)-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleThe Mechanism of Spinal Cord Stimulation in Animal Model of Neuropathic Pain-
dc.typeConference_Paper-
dc.identifier.emailCheung, CW: cheucw@hku.hk-
dc.identifier.authorityCheung, CW=rp00244-
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros312899-
dc.identifier.volume16-
dc.identifier.spage38-
dc.identifier.epage38-
dc.publisher.placeUnited Kingdom-
dc.identifier.partofdoi10.1177/1744806920907173-

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