Influencing factors for quality of life in patients over 12-months after diagnosis of non-small cell lung cancer

Abstract

目的·评估首诊至调查时间病程≥12个月的非小细胞肺癌（non-small cell lung cancer，NSCLC）患者的生活质量，探讨相关影响因素。方法·采用FACT-L（Functional Assessment of Cancer Therapy–Lung）量表对111名纳入研究的患者的生活质量进行评价，自制问卷收集患者人口学特征、医疗信息和情绪感受。结果·研究从治疗及患者主观感受2个路径探讨NSCLC患者生活质量的影响因素。单因素Logistic回归分析显示低生活质量的风险因素为：自卑孤独感、骨转移、病理类型、化学治疗周期、年龄、共住家庭成员结构和经济困难。结论·肺癌患者生活质量影响因素多元而广泛，情绪及症状管理亟待重视。 Objective · To examine quality of life and its influencing factors in patients over 12 months after diagnosis of non-small cell lung cancer (NSCLC). Methods · A total of 111 patients included in the study completed the self-reported measures. Quality of life was measured using Functional Assessment of Cancer Therapy–Lung. Other measures included socio-demographic characteristics, disease- and treatment-related information, and emotional feelings. Results · The factors influencing the quality of life of NSCLC patients were investigated two approaches: treatment and subjective feeling. Univariate Logistic regression analysis found the risk factors for low quality of life included sense of low self-esteem and loneliness, bone metastasis, pathological type, chemotherapy cycle, age, cohabitant type and financial burden. Conclusion · The factors associated with quality of life in lung cancer patients are diverse and extensive, and it warrants attention on psychological support and symptom management for these patients.