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Article: Capillary-Driven Flow Microfluidics Combined with Smartphone Detection: An Emerging Tool for Point-of-Care Diagnostics

TitleCapillary-Driven Flow Microfluidics Combined with Smartphone Detection: An Emerging Tool for Point-of-Care Diagnostics
Authors
KeywordsMicrofluidics
Point-of-care diagnostics
Antimicrobial resistance
Lab-on-a-chip
Capillary-driven flow
Capillary action
Detections
Smartphone imaging
Issue Date2020
PublisherMDPI AG. The Journal's web site is located at http://www.mdpi.com/journal/diagnostics
Citation
Diagnostics, 2020, v. 10 n. 8, article no. 509 How to Cite?
AbstractPoint-of-care (POC) or near-patient testing allows clinicians to accurately achieve real-time diagnostic results performed at or near to the patient site. The outlook of POC devices is to provide quicker analyses that can lead to well-informed clinical decisions and hence improve the health of patients at the point-of-need. Microfluidics plays an important role in the development of POC devices. However, requirements of handling expertise, pumping systems and complex fluidic controls make the technology unaffordable to the current healthcare systems in the world. In recent years, capillary-driven flow microfluidics has emerged as an attractive microfluidic-based technology to overcome these limitations by offering robust, cost-effective and simple-to-operate devices. The internal wall of the microchannels can be pre-coated with reagents, and by merely dipping the device into the patient sample, the sample can be loaded into the microchannel driven by capillary forces and can be detected via handheld or smartphone-based detectors. The capabilities of capillary-driven flow devices have not been fully exploited in developing POC diagnostics, especially for antimicrobial resistance studies in clinical settings. The purpose of this review is to open up this field of microfluidics to the ever-expanding microfluidic-based scientific community.
Persistent Identifierhttp://hdl.handle.net/10722/302076
ISSN
2023 Impact Factor: 3.0
2023 SCImago Journal Rankings: 0.667
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHassan, SU-
dc.contributor.authorTariq, A-
dc.contributor.authorNoreen, A-
dc.contributor.authorDonia, H-
dc.contributor.authorZaidi, SZJ-
dc.contributor.authorBokhari, H-
dc.contributor.authorZhang, X-
dc.date.accessioned2021-08-21T03:31:14Z-
dc.date.available2021-08-21T03:31:14Z-
dc.date.issued2020-
dc.identifier.citationDiagnostics, 2020, v. 10 n. 8, article no. 509-
dc.identifier.issn2075-4418-
dc.identifier.urihttp://hdl.handle.net/10722/302076-
dc.description.abstractPoint-of-care (POC) or near-patient testing allows clinicians to accurately achieve real-time diagnostic results performed at or near to the patient site. The outlook of POC devices is to provide quicker analyses that can lead to well-informed clinical decisions and hence improve the health of patients at the point-of-need. Microfluidics plays an important role in the development of POC devices. However, requirements of handling expertise, pumping systems and complex fluidic controls make the technology unaffordable to the current healthcare systems in the world. In recent years, capillary-driven flow microfluidics has emerged as an attractive microfluidic-based technology to overcome these limitations by offering robust, cost-effective and simple-to-operate devices. The internal wall of the microchannels can be pre-coated with reagents, and by merely dipping the device into the patient sample, the sample can be loaded into the microchannel driven by capillary forces and can be detected via handheld or smartphone-based detectors. The capabilities of capillary-driven flow devices have not been fully exploited in developing POC diagnostics, especially for antimicrobial resistance studies in clinical settings. The purpose of this review is to open up this field of microfluidics to the ever-expanding microfluidic-based scientific community.-
dc.languageeng-
dc.publisherMDPI AG. The Journal's web site is located at http://www.mdpi.com/journal/diagnostics-
dc.relation.ispartofDiagnostics-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectMicrofluidics-
dc.subjectPoint-of-care diagnostics-
dc.subjectAntimicrobial resistance-
dc.subjectLab-on-a-chip-
dc.subjectCapillary-driven flow-
dc.subjectCapillary action-
dc.subjectDetections-
dc.subjectSmartphone imaging-
dc.titleCapillary-Driven Flow Microfluidics Combined with Smartphone Detection: An Emerging Tool for Point-of-Care Diagnostics-
dc.typeArticle-
dc.identifier.emailHassan, SU: suhassan@hku.hk-
dc.identifier.authorityHassan, SU=rp02857-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3390/diagnostics10080509-
dc.identifier.pmid32708045-
dc.identifier.pmcidPMC7459612-
dc.identifier.scopuseid_2-s2.0-85089893855-
dc.identifier.hkuros324380-
dc.identifier.volume10-
dc.identifier.issue8-
dc.identifier.spagearticle no. 509-
dc.identifier.epagearticle no. 509-
dc.identifier.isiWOS:000567324400001-
dc.publisher.placeSwitzerland-

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