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Conference Paper: The prognostic value of human papilloma virus infection in oral cavity squamous cell carcinoma: a systematic review and meta-analysis

TitleThe prognostic value of human papilloma virus infection in oral cavity squamous cell carcinoma: a systematic review and meta-analysis
Authors
Issue Date2019
PublisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijom
Citation
The 24th International Conference on Oral and Maxillofacial Surgery (ICOMS), Rio de Janeiro, Brazil, 21-24 May 2019. In International Journal of Oral and Maxillofacial Surgery, 2019, v. 48 n. Suppl. 1, p. 76 How to Cite?
AbstractBackground: Human papilloma virus (HPV) infection has been confirmed as a favorable prognostic factor in oropharyngeal cancer. However, the prognostic value of HPV in oral cavity squamous cell carcinoma is still unclear. Objectives: This study aimed to review all published articles and conduct a meta-analysis on the overall survival (OS), diseases free survival (DFS), and diseases specific survival (DSS) of HPV positive and negative HPV oral cavity squamous cell carcinoma. Methods: A systematic literature review was conducted in accordance with PRISMA statement checklist and flowchart in PubMed, EMBASE, and MEDLINE databases. Findings: A total of seventeen articles were included in this study. The hazard ratio (HR) for OS, DFS, and DSS comparing HPV positive and negative oral cavity squamous cell carcinoma were 1.47(95% CI = 0.98-2.22), 1.22(95% CI = 0.81-1.84), and 0.96 (95% CI = 0.50-1.87) respectively, suggesting no significant difference detected. Conclusion: Our results showed there was no significant difference in OS, DFS, and DSS between HPV-positive and negative oral cavity cancer patients. Therefore, HPV infection is not a prognostic factor for oral cavity squamous cell carcinoma.
DescriptionFree Paper Oral Presentation - Head and Neck Oncology
Persistent Identifierhttp://hdl.handle.net/10722/302488
ISSN
2023 Impact Factor: 2.2
2023 SCImago Journal Rankings: 0.875

 

DC FieldValueLanguage
dc.contributor.authorChristianto, S-
dc.contributor.authorLi, KY-
dc.contributor.authorHuang, TH-
dc.contributor.authorSu, Y-
dc.date.accessioned2021-09-06T03:33:01Z-
dc.date.available2021-09-06T03:33:01Z-
dc.date.issued2019-
dc.identifier.citationThe 24th International Conference on Oral and Maxillofacial Surgery (ICOMS), Rio de Janeiro, Brazil, 21-24 May 2019. In International Journal of Oral and Maxillofacial Surgery, 2019, v. 48 n. Suppl. 1, p. 76-
dc.identifier.issn0901-5027-
dc.identifier.urihttp://hdl.handle.net/10722/302488-
dc.descriptionFree Paper Oral Presentation - Head and Neck Oncology-
dc.description.abstractBackground: Human papilloma virus (HPV) infection has been confirmed as a favorable prognostic factor in oropharyngeal cancer. However, the prognostic value of HPV in oral cavity squamous cell carcinoma is still unclear. Objectives: This study aimed to review all published articles and conduct a meta-analysis on the overall survival (OS), diseases free survival (DFS), and diseases specific survival (DSS) of HPV positive and negative HPV oral cavity squamous cell carcinoma. Methods: A systematic literature review was conducted in accordance with PRISMA statement checklist and flowchart in PubMed, EMBASE, and MEDLINE databases. Findings: A total of seventeen articles were included in this study. The hazard ratio (HR) for OS, DFS, and DSS comparing HPV positive and negative oral cavity squamous cell carcinoma were 1.47(95% CI = 0.98-2.22), 1.22(95% CI = 0.81-1.84), and 0.96 (95% CI = 0.50-1.87) respectively, suggesting no significant difference detected. Conclusion: Our results showed there was no significant difference in OS, DFS, and DSS between HPV-positive and negative oral cavity cancer patients. Therefore, HPV infection is not a prognostic factor for oral cavity squamous cell carcinoma.-
dc.languageeng-
dc.publisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijom-
dc.relation.ispartofInternational Journal of Oral and Maxillofacial Surgery-
dc.relation.ispartofThe 24th International Conference on Oral and Maxillofacial Surgery (ICOMS), 2019-
dc.titleThe prognostic value of human papilloma virus infection in oral cavity squamous cell carcinoma: a systematic review and meta-analysis-
dc.typeConference_Paper-
dc.identifier.emailSu, Y: richsu@hku.hk-
dc.identifier.authoritySu, Y=rp01916-
dc.description.natureabstract-
dc.identifier.doi10.1016/j.ijom.2019.03.228-
dc.identifier.hkuros324662-
dc.identifier.volume48-
dc.identifier.issueSuppl. 1-
dc.identifier.spage76-
dc.identifier.epage76-
dc.publisher.placeUnited Kingdom-

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