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Article: The analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block combined with oral multimodal analgesia in comparison with oral multimodal analgesia after caesarean delivery: a randomized controlled trial

TitleThe analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block combined with oral multimodal analgesia in comparison with oral multimodal analgesia after caesarean delivery: a randomized controlled trial
Authors
KeywordsTransversus abdominis plane block
Oral analgesics
Caesarean deliver
Issue Date2021
PublisherBioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcanesthesiol/
Citation
BMC Anesthesiology, 2021, v. 21, p. article no. 7 How to Cite?
AbstractBackground: The transversus abdominis plane (TAP) block is used increasingly in parturients after caesarean delivery. This is a randomized controlled trial to evaluate the effectiveness of bilateral single-shot of TAP blocks in patients who received multimodal oral analgesia for postoperative pain relief. Methods: Parturients who were scheduled for elective caesarean delivery under spinal anaesthesia were recruited and randomized to receive bilateral single-shot of TAP blocks or placebo in addition to multimodal oral analgesia which consisted of regular tramadol, celecoxib and paracetamol, with oral oxycodone used as a rescue for breakthrough pain. Only parturients in the TAP group would receive the TAP blocks with an injection of 15 ml (0.25%) ropivacaine on each side under aseptic techniques. All the parturients were evaluated for pain or related complications in the first 24 h after surgery. The primary outcome is the percentage of parturients who required oxycodone as a rescue analgesia. Results: Eighty and 79 parturients were allocated to the TAP and placebo group respectively. Nine out of 79 (11.4%) parturients in the TAP group and 15 out of 73 (20.5%) parturients in the placebo group required oxycodone for breakthrough pain, P = 0.122. Conclusions: Bilateral single-shot of TAP blocks confer little additional benefit when a multimodal oral analgesic regimen is used for pain control after caesarean section under spinal anaesthesia. Trial registration: Clinical Trial Registry of China (http://www.chictr.org.cn) identifier: ChiCTR-INR-16010130, retrospectively registered on Dec 12, 2016.
Descriptioneid_2-s2.0-85098855945
Persistent Identifierhttp://hdl.handle.net/10722/304483
ISSN
2023 Impact Factor: 2.3
2023 SCImago Journal Rankings: 0.658
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYU, Y-
dc.contributor.authorGAO, S-
dc.contributor.authorYuen, VMY-
dc.contributor.authorChoi, SW-
dc.contributor.authorXU, X-
dc.date.accessioned2021-09-23T09:00:40Z-
dc.date.available2021-09-23T09:00:40Z-
dc.date.issued2021-
dc.identifier.citationBMC Anesthesiology, 2021, v. 21, p. article no. 7-
dc.identifier.issn1471-2253-
dc.identifier.urihttp://hdl.handle.net/10722/304483-
dc.descriptioneid_2-s2.0-85098855945-
dc.description.abstractBackground: The transversus abdominis plane (TAP) block is used increasingly in parturients after caesarean delivery. This is a randomized controlled trial to evaluate the effectiveness of bilateral single-shot of TAP blocks in patients who received multimodal oral analgesia for postoperative pain relief. Methods: Parturients who were scheduled for elective caesarean delivery under spinal anaesthesia were recruited and randomized to receive bilateral single-shot of TAP blocks or placebo in addition to multimodal oral analgesia which consisted of regular tramadol, celecoxib and paracetamol, with oral oxycodone used as a rescue for breakthrough pain. Only parturients in the TAP group would receive the TAP blocks with an injection of 15 ml (0.25%) ropivacaine on each side under aseptic techniques. All the parturients were evaluated for pain or related complications in the first 24 h after surgery. The primary outcome is the percentage of parturients who required oxycodone as a rescue analgesia. Results: Eighty and 79 parturients were allocated to the TAP and placebo group respectively. Nine out of 79 (11.4%) parturients in the TAP group and 15 out of 73 (20.5%) parturients in the placebo group required oxycodone for breakthrough pain, P = 0.122. Conclusions: Bilateral single-shot of TAP blocks confer little additional benefit when a multimodal oral analgesic regimen is used for pain control after caesarean section under spinal anaesthesia. Trial registration: Clinical Trial Registry of China (http://www.chictr.org.cn) identifier: ChiCTR-INR-16010130, retrospectively registered on Dec 12, 2016.-
dc.languageeng-
dc.publisherBioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcanesthesiol/-
dc.relation.ispartofBMC Anesthesiology-
dc.rightsBMC Anesthesiology. Copyright © BioMed Central Ltd.-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectTransversus abdominis plane block-
dc.subjectOral analgesics-
dc.subjectCaesarean deliver-
dc.titleThe analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block combined with oral multimodal analgesia in comparison with oral multimodal analgesia after caesarean delivery: a randomized controlled trial-
dc.typeArticle-
dc.identifier.emailYuen, VMY: vtang131@hkucc.hku.hk-
dc.identifier.emailChoi, SW: htswchoi@HKUCC-COM.hku.hk-
dc.identifier.authorityChoi, SW=rp02552-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1186/s12871-020-01223-3-
dc.identifier.pmid33413104-
dc.identifier.pmcidPMC7789306-
dc.identifier.scopuseid_2-s2.0-85098855945-
dc.identifier.hkuros325344-
dc.identifier.volume21-
dc.identifier.spagearticle no. 7-
dc.identifier.epagearticle no. 7-
dc.identifier.isiWOS:000609188800001-
dc.publisher.placeUnited Kingdom-

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