File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Beyond the mean: quantile regression to differentiate the distributional effects of ambient PM2.5 constituents on sperm quality among men

TitleBeyond the mean: quantile regression to differentiate the distributional effects of ambient PM2.5 constituents on sperm quality among men
Authors
KeywordsDistributional effect
Fine particulate matter constituents
Quantile regression
Semen quality
Issue Date2021
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/chemosphere
Citation
Chemosphere, 2021, v. 285, p. article no. 131496 How to Cite?
AbstractAmbient PM2.5 (particulate matter ≤ 2.5 μm in aerodynamic diameter) constituents have been related to mean changes in semen quality, but focusing on the mean response may not well capture distributional and heterogeneous effects of PM2.5 constituents on semen quality. In this study, 2314 semen samples of 622 men between Jan 1, 2019 and Dec 31, 2019 from Guangdong Human Sperm Bank were subjected to semen quality analysis. Daily average concentrations of PM2.5 constituents including 4 water-soluble ions and 15 metals/metalloid were measured for 7 days per month at 3 fixed atmospheric pollutant monitoring stations. We used quantile regression for longitudinal data to examine whether the associations between PM2.5 constituents and quality indicators of semen varied across quantiles of outcome distribution. Heterogeneous associations were found between PM2.5 constituents and sperm quality across different quantiles. An interquartile range (14.0 μg/m3) increase in PM2.5 mass was negatively associated with lower tails of sperm concentration and upper tails of sperm count distribution. PM2.5 vanadium exposure was significantly related to the 90th percentile of sperm count distribution, but not to the lower quantiles. In addition, those subjects with relatively high sperm motility were more susceptible to sulfate, chromium, and manganese constituents in PM2.5. Our results indicate that PM2.5 and certain constituents were associated with sperm quality, especially sperm motility, and the associations are more pronounced in men with relatively high or low sperm motility.
Persistent Identifierhttp://hdl.handle.net/10722/304529
ISSN
2020 Impact Factor: 7.086
2020 SCImago Journal Rankings: 1.632
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWu, H-
dc.contributor.authorYu, X-
dc.contributor.authorWang, Q-
dc.contributor.authorZeng, Q-
dc.contributor.authorChen, Y-
dc.contributor.authorLv, J-
dc.contributor.authorWu, Y-
dc.contributor.authorZhou, H-
dc.contributor.authorZhang, H-
dc.contributor.authorLiu, M-
dc.contributor.authorZheng, M-
dc.contributor.authorZhao, Q-
dc.contributor.authorGuo, P-
dc.contributor.authorFeng, W-
dc.contributor.authorZhang, X-
dc.contributor.authorTian, L-
dc.date.accessioned2021-09-23T09:01:20Z-
dc.date.available2021-09-23T09:01:20Z-
dc.date.issued2021-
dc.identifier.citationChemosphere, 2021, v. 285, p. article no. 131496-
dc.identifier.issn0045-6535-
dc.identifier.urihttp://hdl.handle.net/10722/304529-
dc.description.abstractAmbient PM2.5 (particulate matter ≤ 2.5 μm in aerodynamic diameter) constituents have been related to mean changes in semen quality, but focusing on the mean response may not well capture distributional and heterogeneous effects of PM2.5 constituents on semen quality. In this study, 2314 semen samples of 622 men between Jan 1, 2019 and Dec 31, 2019 from Guangdong Human Sperm Bank were subjected to semen quality analysis. Daily average concentrations of PM2.5 constituents including 4 water-soluble ions and 15 metals/metalloid were measured for 7 days per month at 3 fixed atmospheric pollutant monitoring stations. We used quantile regression for longitudinal data to examine whether the associations between PM2.5 constituents and quality indicators of semen varied across quantiles of outcome distribution. Heterogeneous associations were found between PM2.5 constituents and sperm quality across different quantiles. An interquartile range (14.0 μg/m3) increase in PM2.5 mass was negatively associated with lower tails of sperm concentration and upper tails of sperm count distribution. PM2.5 vanadium exposure was significantly related to the 90th percentile of sperm count distribution, but not to the lower quantiles. In addition, those subjects with relatively high sperm motility were more susceptible to sulfate, chromium, and manganese constituents in PM2.5. Our results indicate that PM2.5 and certain constituents were associated with sperm quality, especially sperm motility, and the associations are more pronounced in men with relatively high or low sperm motility.-
dc.languageeng-
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/chemosphere-
dc.relation.ispartofChemosphere-
dc.subjectDistributional effect-
dc.subjectFine particulate matter constituents-
dc.subjectQuantile regression-
dc.subjectSemen quality-
dc.titleBeyond the mean: quantile regression to differentiate the distributional effects of ambient PM2.5 constituents on sperm quality among men-
dc.typeArticle-
dc.identifier.emailTian, L: linweit@hku.hk-
dc.identifier.authorityTian, L=rp01991-
dc.identifier.doi10.1016/j.chemosphere.2021.131496-
dc.identifier.pmid34329140-
dc.identifier.scopuseid_2-s2.0-85109900799-
dc.identifier.hkuros325516-
dc.identifier.volume285-
dc.identifier.spagearticle no. 131496-
dc.identifier.epagearticle no. 131496-
dc.identifier.isiWOS:000703680200010-
dc.publisher.placeUnited Kingdom-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats