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Article: Ag3PO4 decorated black urchin-like defective TiO2 for rapid and long-term bacteria-killing under visible light

TitleAg3PO4 decorated black urchin-like defective TiO2 for rapid and long-term bacteria-killing under visible light
Authors
KeywordsAntibacterial
Ag3PO4
Defective TiO2
Photocatalytic
Puncture
Issue Date2021
PublisherElsevier B.V. on behalf of KeAi Communications Co. Ltd. The Journal's web site is located at http://www.sciencedirect.com/science/journal/2452199X
Citation
Bioactive Materials, 2021, v. 6 n. 6, p. 1575-1587 How to Cite?
AbstractBoth phototherapy via photocatalysts and physical puncture by artificial nanostructures are promising substitutes for antibiotics when treating drug-resistant bacterial infectious diseases. However, the photodynamic therapeutic efficacy of photocatalysts is seriously restricted by the rapid recombination of photogenerated electron–hole pairs. Meanwhile, the nanostructures of physical puncture are limited to two-dimensional (2D) platforms, and they cannot be fully used yet. Thus, this research developed a synergistic system of Ag3PO4 nanoparticles (NPs), decorated with black urchin-like defective TiO2 (BU–TiO2-X/Ag3PO4). These NPs had a decreased bandgap compared to BU-TiO2-X, and BU-TiO2-X/Ag3PO4 (3:1) exhibited the lowest bandgap and the highest separation efficiency for photogenerated electron–hole pairs. After combination with BU-TiO2-X, the photostability of Ag3PO4 improved because the oxygen vacancy of BU-TiO2-X retards the reduction of Ag+ in Ag3PO4 into Ag0, thus reducing its toxicity. In addition, the nanospikes on the surface of BU-TiO2-X can, from all directions, physically puncture bacterial cells, thus assisting the hybrid's photodynamic therapeutic effects, alongside the small amount of Ag+ released from Ag3PO4. This achieves synergy, endowing the hybrid with high antibacterial efficacy of 99.76 ± 0.15% and 99.85 ± 0.09% against Escherichia coli and Staphylococcus aureus, respectively, after light irradiation for 20 min followed by darkness for 12 h. It is anticipated that these findings may bring new insight for developing synergistic treatment strategies against bacterial infectious diseases or pathogenic bacterial polluted environments.
Persistent Identifierhttp://hdl.handle.net/10722/305012
ISSN
2020 SCImago Journal Rankings: 2.172
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorXU, Y-
dc.contributor.authorLIU, X-
dc.contributor.authorZHENG, Y-
dc.contributor.authorLI, C-
dc.contributor.authorYeung, KWK-
dc.contributor.authorCUI, Z-
dc.contributor.authorLIANG, Y-
dc.contributor.authorLI, Z-
dc.contributor.authorZHU, S-
dc.contributor.authorWU, S-
dc.date.accessioned2021-10-05T02:38:29Z-
dc.date.available2021-10-05T02:38:29Z-
dc.date.issued2021-
dc.identifier.citationBioactive Materials, 2021, v. 6 n. 6, p. 1575-1587-
dc.identifier.issn2452-199X-
dc.identifier.urihttp://hdl.handle.net/10722/305012-
dc.description.abstractBoth phototherapy via photocatalysts and physical puncture by artificial nanostructures are promising substitutes for antibiotics when treating drug-resistant bacterial infectious diseases. However, the photodynamic therapeutic efficacy of photocatalysts is seriously restricted by the rapid recombination of photogenerated electron–hole pairs. Meanwhile, the nanostructures of physical puncture are limited to two-dimensional (2D) platforms, and they cannot be fully used yet. Thus, this research developed a synergistic system of Ag3PO4 nanoparticles (NPs), decorated with black urchin-like defective TiO2 (BU–TiO2-X/Ag3PO4). These NPs had a decreased bandgap compared to BU-TiO2-X, and BU-TiO2-X/Ag3PO4 (3:1) exhibited the lowest bandgap and the highest separation efficiency for photogenerated electron–hole pairs. After combination with BU-TiO2-X, the photostability of Ag3PO4 improved because the oxygen vacancy of BU-TiO2-X retards the reduction of Ag+ in Ag3PO4 into Ag0, thus reducing its toxicity. In addition, the nanospikes on the surface of BU-TiO2-X can, from all directions, physically puncture bacterial cells, thus assisting the hybrid's photodynamic therapeutic effects, alongside the small amount of Ag+ released from Ag3PO4. This achieves synergy, endowing the hybrid with high antibacterial efficacy of 99.76 ± 0.15% and 99.85 ± 0.09% against Escherichia coli and Staphylococcus aureus, respectively, after light irradiation for 20 min followed by darkness for 12 h. It is anticipated that these findings may bring new insight for developing synergistic treatment strategies against bacterial infectious diseases or pathogenic bacterial polluted environments.-
dc.languageeng-
dc.publisherElsevier B.V. on behalf of KeAi Communications Co. Ltd. The Journal's web site is located at http://www.sciencedirect.com/science/journal/2452199X-
dc.relation.ispartofBioactive Materials-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAntibacterial-
dc.subjectAg3PO4-
dc.subjectDefective TiO2-
dc.subjectPhotocatalytic-
dc.subjectPuncture-
dc.titleAg3PO4 decorated black urchin-like defective TiO2 for rapid and long-term bacteria-killing under visible light-
dc.typeArticle-
dc.identifier.emailYeung, KWK: wkkyeung@hku.hk-
dc.identifier.authorityYeung, KWK=rp00309-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1016/j.bioactmat.2020.11.013-
dc.identifier.pmid33294735-
dc.identifier.pmcidPMC7691127-
dc.identifier.scopuseid_2-s2.0-85096680817-
dc.identifier.hkuros326139-
dc.identifier.volume6-
dc.identifier.issue6-
dc.identifier.spage1575-
dc.identifier.epage1587-
dc.identifier.isiWOS:000630522400006-
dc.publisher.placeChina-

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