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Article: Effectiveness of interventions for people living with dementia and their carers in Chinese communities: protocol for a systematic review and meta-analysis of randomised controlled trials

TitleEffectiveness of interventions for people living with dementia and their carers in Chinese communities: protocol for a systematic review and meta-analysis of randomised controlled trials
Authors
Keywordsdementia
health policy
old age psychiatry
public health
Issue Date2021
PublisherBMJ Publishing Group: BMJ Open. The Journal's web site is located at http://bmjopen.bmj.com
Citation
BMJ Open, 2021, v. 11 n. 8, p. article no. e047560 How to Cite?
AbstractIntroduction: As the largest and most rapidly ageing population, Chinese people are now the major driver of the continued growth in dementia prevalence globally. The need for evidence-based interventions in Chinese communities is urgent. Although a wide range of pharmacological and non-pharmacological interventions for dementia have been trialled in Chinese populations, the evidence has not been systematically synthesised. This systematic review and meta-analysis aims to map out the interventions for people living with dementia and their carers in Chinese communities worldwide and compare the effectiveness of these interventions. Methods and analysis: This protocol followed the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols checklist. We will search Chinese (China National Knowledge Infrastructure, WanFang DATA) and English bibliographical databases (MEDLINE, EMBASE, PsycINFO, CINAHL Plus, Global Health, WHO Global Index Medicus, Virtual Health Library, Cochrane CENTRAL, Social Care Online, BASE, MODelling Outcome and cost impacts of interventions for DEMentia (MODEM) Toolkit, Cochrane Database of Systematic Reviews), complemented by hand searching of reference lists. We will include studies evaluating the effectiveness of interventions for dementia or mild cognitive impairment in Chinese populations, using a randomised controlled trial design, and published between January 2008 and June 2020. We will use a standardised form to extract data and Version 2 of the Cochrane risk-of-bias tool for randomised trials to assess the risk of bias of the included studies. Collected data will be fully interpreted with narrative synthesis and analysed using pairwise and network meta-analyses to pool intervention effects where sufficient information is available. We will perform subgroup analysis and meta-regression to explore potential reasons for heterogeneity. Ethics and dissemination: No formal ethics approval is required for this protocol. The findings will facilitate the development of studies on interventions for dementia and timely inform dementia policymaking and practice. Planned dissemination channels include peer-reviewed publications, conference presentations, public events and websites. PROSPERO registration number: CRD42019134135.
Persistent Identifierhttp://hdl.handle.net/10722/305888
ISSN
2023 Impact Factor: 2.4
2023 SCImago Journal Rankings: 0.971
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorShi, C-
dc.contributor.authorCHEN, S-
dc.contributor.authorSalcher-Konrad, M-
dc.contributor.authorChoy, JCP-
dc.contributor.authorLuo, H-
dc.contributor.authorLeung, DKY-
dc.contributor.authorCAI, X-
dc.contributor.authorZENG, Y-
dc.contributor.authorDai, R-
dc.contributor.authorComas-Herrera, A-
dc.contributor.authorMcDaid, D-
dc.contributor.authorKnapp, M-
dc.contributor.authorWong, G-
dc.date.accessioned2021-10-20T10:15:45Z-
dc.date.available2021-10-20T10:15:45Z-
dc.date.issued2021-
dc.identifier.citationBMJ Open, 2021, v. 11 n. 8, p. article no. e047560-
dc.identifier.issn2044-6055-
dc.identifier.urihttp://hdl.handle.net/10722/305888-
dc.description.abstractIntroduction: As the largest and most rapidly ageing population, Chinese people are now the major driver of the continued growth in dementia prevalence globally. The need for evidence-based interventions in Chinese communities is urgent. Although a wide range of pharmacological and non-pharmacological interventions for dementia have been trialled in Chinese populations, the evidence has not been systematically synthesised. This systematic review and meta-analysis aims to map out the interventions for people living with dementia and their carers in Chinese communities worldwide and compare the effectiveness of these interventions. Methods and analysis: This protocol followed the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols checklist. We will search Chinese (China National Knowledge Infrastructure, WanFang DATA) and English bibliographical databases (MEDLINE, EMBASE, PsycINFO, CINAHL Plus, Global Health, WHO Global Index Medicus, Virtual Health Library, Cochrane CENTRAL, Social Care Online, BASE, MODelling Outcome and cost impacts of interventions for DEMentia (MODEM) Toolkit, Cochrane Database of Systematic Reviews), complemented by hand searching of reference lists. We will include studies evaluating the effectiveness of interventions for dementia or mild cognitive impairment in Chinese populations, using a randomised controlled trial design, and published between January 2008 and June 2020. We will use a standardised form to extract data and Version 2 of the Cochrane risk-of-bias tool for randomised trials to assess the risk of bias of the included studies. Collected data will be fully interpreted with narrative synthesis and analysed using pairwise and network meta-analyses to pool intervention effects where sufficient information is available. We will perform subgroup analysis and meta-regression to explore potential reasons for heterogeneity. Ethics and dissemination: No formal ethics approval is required for this protocol. The findings will facilitate the development of studies on interventions for dementia and timely inform dementia policymaking and practice. Planned dissemination channels include peer-reviewed publications, conference presentations, public events and websites. PROSPERO registration number: CRD42019134135.-
dc.languageeng-
dc.publisherBMJ Publishing Group: BMJ Open. The Journal's web site is located at http://bmjopen.bmj.com-
dc.relation.ispartofBMJ Open-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectdementia-
dc.subjecthealth policy-
dc.subjectold age psychiatry-
dc.subjectpublic health-
dc.titleEffectiveness of interventions for people living with dementia and their carers in Chinese communities: protocol for a systematic review and meta-analysis of randomised controlled trials-
dc.typeArticle-
dc.identifier.emailShi, C: cs2019@hku.hk-
dc.identifier.emailChoy, JCP: cpchoy@hku.hk-
dc.identifier.emailLuo, H: haoluo@hku.hk-
dc.identifier.emailLeung, DKY: daralky@hku.hk-
dc.identifier.emailDai, R: rdai@hku.hk-
dc.identifier.emailWong, G: ghywong@hku.hk-
dc.identifier.authorityLuo, H=rp02317-
dc.identifier.authorityWong, G=rp01850-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1136/bmjopen-2020-047560-
dc.identifier.pmid34404702-
dc.identifier.pmcidPMC8372806-
dc.identifier.scopuseid_2-s2.0-85113564765-
dc.identifier.hkuros326951-
dc.identifier.volume11-
dc.identifier.issue8-
dc.identifier.spagearticle no. e047560-
dc.identifier.epagearticle no. e047560-
dc.identifier.isiWOS:000686260400025-
dc.publisher.placeUnited Kingdom-

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