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Article: Omega-3 supplementation, child antisocial behavior, and psychopathic personality: a randomized, double-blind, placebo-controlled, stratified, parallel group trial

TitleOmega-3 supplementation, child antisocial behavior, and psychopathic personality: a randomized, double-blind, placebo-controlled, stratified, parallel group trial
Authors
KeywordsOmega-3
Antisocial
Aggression
Psychopathy
Randomized controlled trial
Issue Date2021
PublisherSpringer Medizin. The Journal's web site is located at http://www.springer.com/steinkopff/psychiatrie/journal/787
Citation
European Child & Adolescent Psychiatry, 2021, v. 30 n. 2, p. 303-312 How to Cite?
AbstractWhile some RCTs have observed efficacy for omega-3 supplementation in reducing antisocial behavior, the role of psychopathic personality and gender in moderating treatment outcome has not been examined. This study examines whether omega-3 supplementation reduces antisocial behavior, and whether any treatment effects are a function of gender and psychopathy. Three hundred and twenty-four schoolchildren with a mean age of 11.9 years were randomized into 3 groups: omega-3 (N = 108), placebo (N = 110), and no-treatment controls (N = 106). Parent and child reports of child antisocial and aggressive behavior and psychopathic-like personality were collected at 0 months (baseline), 6 months (end of treatment), and 12 months (6 months post-treatment). A group × time × gender interaction (p = .016) indicated that only females in the omega-3 group showed a significant reduction in antisocial behavior 6 months post-treatment compared to baseline (d = .35), whereas the females in the two control groups showed no change over time. A group x time x psychopathy interaction (p < .006) was also observed, with psychopathic personality levels moderating treatment outcome. Children in the omega-3 group with high (but not low) psychopathic-like personality showed significant improvements in child-reported antisocial behavior at the end of treatment (d = .19) Results suggest that omega-3 supplementation may be helpful in reducing childhood antisocial and aggressive behavior in females, and those with psychopathic-like personalities.
Persistent Identifierhttp://hdl.handle.net/10722/306209
ISSN
2023 Impact Factor: 6.0
2023 SCImago Journal Rankings: 2.175
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorRaine, A-
dc.contributor.authorFung, ALC-
dc.contributor.authorGao, Y-
dc.contributor.authorLee, TMC-
dc.date.accessioned2021-10-20T10:20:21Z-
dc.date.available2021-10-20T10:20:21Z-
dc.date.issued2021-
dc.identifier.citationEuropean Child & Adolescent Psychiatry, 2021, v. 30 n. 2, p. 303-312-
dc.identifier.issn1018-8827-
dc.identifier.urihttp://hdl.handle.net/10722/306209-
dc.description.abstractWhile some RCTs have observed efficacy for omega-3 supplementation in reducing antisocial behavior, the role of psychopathic personality and gender in moderating treatment outcome has not been examined. This study examines whether omega-3 supplementation reduces antisocial behavior, and whether any treatment effects are a function of gender and psychopathy. Three hundred and twenty-four schoolchildren with a mean age of 11.9 years were randomized into 3 groups: omega-3 (N = 108), placebo (N = 110), and no-treatment controls (N = 106). Parent and child reports of child antisocial and aggressive behavior and psychopathic-like personality were collected at 0 months (baseline), 6 months (end of treatment), and 12 months (6 months post-treatment). A group × time × gender interaction (p = .016) indicated that only females in the omega-3 group showed a significant reduction in antisocial behavior 6 months post-treatment compared to baseline (d = .35), whereas the females in the two control groups showed no change over time. A group x time x psychopathy interaction (p < .006) was also observed, with psychopathic personality levels moderating treatment outcome. Children in the omega-3 group with high (but not low) psychopathic-like personality showed significant improvements in child-reported antisocial behavior at the end of treatment (d = .19) Results suggest that omega-3 supplementation may be helpful in reducing childhood antisocial and aggressive behavior in females, and those with psychopathic-like personalities.-
dc.languageeng-
dc.publisherSpringer Medizin. The Journal's web site is located at http://www.springer.com/steinkopff/psychiatrie/journal/787-
dc.relation.ispartofEuropean Child & Adolescent Psychiatry-
dc.subjectOmega-3-
dc.subjectAntisocial-
dc.subjectAggression-
dc.subjectPsychopathy-
dc.subjectRandomized controlled trial-
dc.titleOmega-3 supplementation, child antisocial behavior, and psychopathic personality: a randomized, double-blind, placebo-controlled, stratified, parallel group trial-
dc.typeArticle-
dc.identifier.emailLee, TMC: tmclee@hku.hk-
dc.identifier.authorityLee, TMC=rp00564-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00787-020-01513-8-
dc.identifier.pmid32222821-
dc.identifier.scopuseid_2-s2.0-85082959379-
dc.identifier.hkuros328012-
dc.identifier.volume30-
dc.identifier.issue2-
dc.identifier.spage303-
dc.identifier.epage312-
dc.identifier.isiWOS:000522000200001-
dc.publisher.placeGermany-

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