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Article: The Incubation Period Distribution of Coronavirus Disease 2019: A Systematic Review and Meta-analysis

TitleThe Incubation Period Distribution of Coronavirus Disease 2019: A Systematic Review and Meta-analysis
Authors
KeywordsCOVID-19
SARS-CoV-2
incubation period
systematic review
Issue Date2021
PublisherOxford University Press, published in association with Clinical Infectious Diseases. The Journal's web site is located at http://www.oxfordjournals.org/our_journals/cid/
Citation
Clinical Infectious Diseases, 2021, v. 73 n. 12, p. 2344-2352 How to Cite?
AbstractIncubation period is an important parameter to inform quarantine period and to study transmission dynamics of infectious diseases. We conducted a systematic review and meta-analysis on published estimates of the incubation period distribution of coronavirus disease 2019, and showed that the pooled median of the point estimates of the mean, median and 95th percentile for incubation period are 6.3 days (range, 1.8–11.9 days), 5.4 days (range, 2.0–17.9 days), and 13.1 days (range, 3.2–17.8 days), respectively. Estimates of the mean and 95th percentile of the incubation period distribution were considerably shorter before the epidemic peak in China compared to after the peak, and variation was also noticed for different choices of methodological approach in estimation. Our findings implied that corrections may be needed before directly applying estimates of incubation period into control of or further studies on emerging infectious diseases.
Persistent Identifierhttp://hdl.handle.net/10722/306262
ISSN
2023 Impact Factor: 8.2
2023 SCImago Journal Rankings: 3.308
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorXIN, H-
dc.contributor.authorWong, YT-
dc.contributor.authorMURPHY, C-
dc.contributor.authorYeung, A-
dc.contributor.authorAli, ST-
dc.contributor.authorWu, P-
dc.contributor.authorCowling, BJ-
dc.date.accessioned2021-10-20T10:21:06Z-
dc.date.available2021-10-20T10:21:06Z-
dc.date.issued2021-
dc.identifier.citationClinical Infectious Diseases, 2021, v. 73 n. 12, p. 2344-2352-
dc.identifier.issn1058-4838-
dc.identifier.urihttp://hdl.handle.net/10722/306262-
dc.description.abstractIncubation period is an important parameter to inform quarantine period and to study transmission dynamics of infectious diseases. We conducted a systematic review and meta-analysis on published estimates of the incubation period distribution of coronavirus disease 2019, and showed that the pooled median of the point estimates of the mean, median and 95th percentile for incubation period are 6.3 days (range, 1.8–11.9 days), 5.4 days (range, 2.0–17.9 days), and 13.1 days (range, 3.2–17.8 days), respectively. Estimates of the mean and 95th percentile of the incubation period distribution were considerably shorter before the epidemic peak in China compared to after the peak, and variation was also noticed for different choices of methodological approach in estimation. Our findings implied that corrections may be needed before directly applying estimates of incubation period into control of or further studies on emerging infectious diseases.-
dc.languageeng-
dc.publisherOxford University Press, published in association with Clinical Infectious Diseases. The Journal's web site is located at http://www.oxfordjournals.org/our_journals/cid/-
dc.relation.ispartofClinical Infectious Diseases-
dc.subjectCOVID-19-
dc.subjectSARS-CoV-2-
dc.subjectincubation period-
dc.subjectsystematic review-
dc.titleThe Incubation Period Distribution of Coronavirus Disease 2019: A Systematic Review and Meta-analysis-
dc.typeArticle-
dc.identifier.emailWong, YT: wongytj@hku.hk-
dc.identifier.emailAli, ST: alist15@hku.hk-
dc.identifier.emailWu, P: pengwu@hku.hk-
dc.identifier.emailCowling, BJ: bcowling@hku.hk-
dc.identifier.authorityAli, ST=rp02673-
dc.identifier.authorityWu, P=rp02025-
dc.identifier.authorityCowling, BJ=rp01326-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1093/cid/ciab501-
dc.identifier.pmid34117868-
dc.identifier.scopuseid_2-s2.0-85114370263-
dc.identifier.hkuros327527-
dc.identifier.volume73-
dc.identifier.issue12-
dc.identifier.spage2344-
dc.identifier.epage2352-
dc.identifier.isiWOS:000743384700028-
dc.publisher.placeUnited States-

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