File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Functional Roles of Neuronal Nitric Oxide Synthase in Neurodegenerative Diseases and Mood Disorders

TitleFunctional Roles of Neuronal Nitric Oxide Synthase in Neurodegenerative Diseases and Mood Disorders
Authors
KeywordsNitric oxide synthase
Alzheimer's disease
mood disorders
Huntington's disease
Parkinson's disease
Issue Date2021
PublisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/car/
Citation
Current Alzheimer Research, 2021, v. 18 n. 10, p. 831-840 How to Cite?
AbstractNitric oxide synthase (NOS) is well known for its involvement in the regulation of the nervous, cardiovascular, and immune systems. Neuronal NOS (nNOS) is the most characterized NOS among all the isoforms. It accounts for most of the production of nitric oxide (NO) in the ner- vous system required for synaptic transmission and neuroplasticity. Previous studies have described the localization of nNOS in specific brain regions of interest. There is substantial evidence in the literature suggesting that nNOS signaling has significant involvement in several disease pathologies. However, the association between brain nNOS expression profiles and disease remains largely unknown. In this review, we attempt to delineate the contribution of nNOS signaling in memory and mood disorders in order to achieve a better understanding of nNOS in disease modulation.
Persistent Identifierhttp://hdl.handle.net/10722/308198
ISSN
2023 Impact Factor: 1.8
2023 SCImago Journal Rankings: 0.584
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorPOON, CH-
dc.contributor.authorTSUI, KC-
dc.contributor.authorChau, SC-
dc.contributor.authorCHONG, PS-
dc.contributor.authorLui, SWY-
dc.contributor.authorAquili, L-
dc.contributor.authorWong, KH-
dc.contributor.authorLim, LW-
dc.date.accessioned2021-11-12T13:43:51Z-
dc.date.available2021-11-12T13:43:51Z-
dc.date.issued2021-
dc.identifier.citationCurrent Alzheimer Research, 2021, v. 18 n. 10, p. 831-840-
dc.identifier.issn1567-2050-
dc.identifier.urihttp://hdl.handle.net/10722/308198-
dc.description.abstractNitric oxide synthase (NOS) is well known for its involvement in the regulation of the nervous, cardiovascular, and immune systems. Neuronal NOS (nNOS) is the most characterized NOS among all the isoforms. It accounts for most of the production of nitric oxide (NO) in the ner- vous system required for synaptic transmission and neuroplasticity. Previous studies have described the localization of nNOS in specific brain regions of interest. There is substantial evidence in the literature suggesting that nNOS signaling has significant involvement in several disease pathologies. However, the association between brain nNOS expression profiles and disease remains largely unknown. In this review, we attempt to delineate the contribution of nNOS signaling in memory and mood disorders in order to achieve a better understanding of nNOS in disease modulation.-
dc.languageeng-
dc.publisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/car/-
dc.relation.ispartofCurrent Alzheimer Research-
dc.subjectNitric oxide synthase-
dc.subjectAlzheimer's disease-
dc.subjectmood disorders-
dc.subjectHuntington's disease-
dc.subjectParkinson's disease-
dc.titleFunctional Roles of Neuronal Nitric Oxide Synthase in Neurodegenerative Diseases and Mood Disorders-
dc.typeArticle-
dc.identifier.emailLim, LW: limlw@hku.hk-
dc.identifier.authorityLim, LW=rp02088-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.2174/1567205018666211022164025-
dc.identifier.pmid34719364-
dc.identifier.scopuseid_2-s2.0-85123387798-
dc.identifier.hkuros330352-
dc.identifier.volume18-
dc.identifier.issue10-
dc.identifier.spage831-
dc.identifier.epage840-
dc.identifier.isiWOS:000735437800006-
dc.publisher.placeNetherlands-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats