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- Publisher Website: 10.1007/s00268-022-06527-8
- PMID: 35313358
- WOS: WOS:000771541800002
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Article: Safety and efficacy of single-session radiofrequency ablation treatment for benign non-toxic multinodular goiter
Title | Safety and efficacy of single-session radiofrequency ablation treatment for benign non-toxic multinodular goiter |
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Authors | |
Issue Date | 2022 |
Publisher | Springer International. The Journal's web site is located at http://www.springer.com/medicine/surgery/journal/268 |
Citation | World Journal of Surgery, 2022, v. 46 n. 7, p. 1704-1710 How to Cite? |
Abstract | Background: Radiofrequency ablation (RFA) is an effective treatment for benign thyroid nodules. However, it remains unclear if ablating multiple nodules in single-session offers comparable safety and efficacy to ablating single nodule. Our study compared early complication rate and 6-month nodule shrinkage between multiple-nodules ablation and single-nodule ablation by RFA.
Methods: Among the 174 eligible patients undergoing RFA of one or more benign thyroid nodules, 85 (48.8%) had single-nodule ablation (group I) while 89 (51.1%) had two or three nodules ablation (group II). The 6-month nodule shrinkage of each nodule (by volume reduction ratio) (VRR) was calculated by (Baseline volume - volume at 6-month)/(Baseline volume)*100 and compared between two groups. To determine independent predictors for VRR, a multivariate analysis was done by logistic regression analysis.
Results: Patients in group II reported significantly higher pain scores during and 2-h after treatment than group I (42.31 vs. 29.66, p = 0.029 and 38.21 vs. 26.18, p = 0.037, respectively). Two vocal cord paresis occurred in each group. 3- and 6-month VRR of the largest nodule were comparable between two groups (67.39% vs. 63.89%, p = 0.248 and 77.29% vs. 73.38%, p = 0.182). Similar 3- and 6-month VRR were observed for 2 and 3 largest nodules in group II. In multivariate analysis, total energy given per nodule volume (OR = 1.007, 95% CI = 1.001-1.012, p = 0.036) was the only independent predictor for 6-month VRR.
Conclusion: In the presence of multinodular goiter, ablating two or more nodules by RFA within one session appears to offer a comparable level of safety and efficacy to ablating single nodule. |
Persistent Identifier | http://hdl.handle.net/10722/311757 |
ISSN | 2023 Impact Factor: 2.3 2023 SCImago Journal Rankings: 0.772 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lang, HHB | - |
dc.contributor.author | Fung, MHM | - |
dc.date.accessioned | 2022-04-01T09:12:49Z | - |
dc.date.available | 2022-04-01T09:12:49Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | World Journal of Surgery, 2022, v. 46 n. 7, p. 1704-1710 | - |
dc.identifier.issn | 0364-2313 | - |
dc.identifier.uri | http://hdl.handle.net/10722/311757 | - |
dc.description.abstract | Background: Radiofrequency ablation (RFA) is an effective treatment for benign thyroid nodules. However, it remains unclear if ablating multiple nodules in single-session offers comparable safety and efficacy to ablating single nodule. Our study compared early complication rate and 6-month nodule shrinkage between multiple-nodules ablation and single-nodule ablation by RFA. Methods: Among the 174 eligible patients undergoing RFA of one or more benign thyroid nodules, 85 (48.8%) had single-nodule ablation (group I) while 89 (51.1%) had two or three nodules ablation (group II). The 6-month nodule shrinkage of each nodule (by volume reduction ratio) (VRR) was calculated by (Baseline volume - volume at 6-month)/(Baseline volume)*100 and compared between two groups. To determine independent predictors for VRR, a multivariate analysis was done by logistic regression analysis. Results: Patients in group II reported significantly higher pain scores during and 2-h after treatment than group I (42.31 vs. 29.66, p = 0.029 and 38.21 vs. 26.18, p = 0.037, respectively). Two vocal cord paresis occurred in each group. 3- and 6-month VRR of the largest nodule were comparable between two groups (67.39% vs. 63.89%, p = 0.248 and 77.29% vs. 73.38%, p = 0.182). Similar 3- and 6-month VRR were observed for 2 and 3 largest nodules in group II. In multivariate analysis, total energy given per nodule volume (OR = 1.007, 95% CI = 1.001-1.012, p = 0.036) was the only independent predictor for 6-month VRR. Conclusion: In the presence of multinodular goiter, ablating two or more nodules by RFA within one session appears to offer a comparable level of safety and efficacy to ablating single nodule. | - |
dc.language | eng | - |
dc.publisher | Springer International. The Journal's web site is located at http://www.springer.com/medicine/surgery/journal/268 | - |
dc.relation.ispartof | World Journal of Surgery | - |
dc.title | Safety and efficacy of single-session radiofrequency ablation treatment for benign non-toxic multinodular goiter | - |
dc.type | Article | - |
dc.identifier.email | Lang, HHB: Blang@hku.hk | - |
dc.identifier.authority | Lang, HHB=rp01828 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1007/s00268-022-06527-8 | - |
dc.identifier.pmid | 35313358 | - |
dc.identifier.hkuros | 332444 | - |
dc.identifier.volume | 46 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 1704 | - |
dc.identifier.epage | 1710 | - |
dc.identifier.isi | WOS:000771541800002 | - |
dc.publisher.place | New York | - |