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- Publisher Website: 10.21037/jtd.2017.12.122
- Scopus: eid_2-s2.0-85050692616
- WOS: WOS:000439487800003
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Article: Atypical antibody responses to influenza
Title | Atypical antibody responses to influenza |
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Authors | |
Keywords | Antibody Heterosubtypic Influenza Neutralizing |
Issue Date | 2018 |
Citation | Journal of Thoracic Disease, 2018, v. 10, p. S2238-S2247 How to Cite? |
Abstract | Influenza viruses undergo rapid antigenic evolution and reassortment, resulting in annual epidemics and the occasional pandemics. Exposure to influenza virus hemagglutinin (HA) and neuraminidase (NA) antigen, either through vaccination or infection, induces an antibody response able to recognize only the homologous antigenic subtype. However, atypical antibody responses recognizing non-homologous influenza subtypes have been reported during infection and vaccination. Here, we review the incidence of these phenomena in published literature and discuss the potential mechanisms underlying them. |
Persistent Identifier | http://hdl.handle.net/10722/312042 |
ISSN | 2023 Impact Factor: 2.1 2023 SCImago Journal Rankings: 0.651 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Hermans, Dalton | - |
dc.contributor.author | Webby, Richard J. | - |
dc.contributor.author | Wong, Sook San | - |
dc.date.accessioned | 2022-04-06T04:32:03Z | - |
dc.date.available | 2022-04-06T04:32:03Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Journal of Thoracic Disease, 2018, v. 10, p. S2238-S2247 | - |
dc.identifier.issn | 2072-1439 | - |
dc.identifier.uri | http://hdl.handle.net/10722/312042 | - |
dc.description.abstract | Influenza viruses undergo rapid antigenic evolution and reassortment, resulting in annual epidemics and the occasional pandemics. Exposure to influenza virus hemagglutinin (HA) and neuraminidase (NA) antigen, either through vaccination or infection, induces an antibody response able to recognize only the homologous antigenic subtype. However, atypical antibody responses recognizing non-homologous influenza subtypes have been reported during infection and vaccination. Here, we review the incidence of these phenomena in published literature and discuss the potential mechanisms underlying them. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of Thoracic Disease | - |
dc.subject | Antibody | - |
dc.subject | Heterosubtypic | - |
dc.subject | Influenza | - |
dc.subject | Neutralizing | - |
dc.title | Atypical antibody responses to influenza | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.21037/jtd.2017.12.122 | - |
dc.identifier.scopus | eid_2-s2.0-85050692616 | - |
dc.identifier.volume | 10 | - |
dc.identifier.spage | S2238 | - |
dc.identifier.epage | S2247 | - |
dc.identifier.eissn | 2077-6624 | - |
dc.identifier.isi | WOS:000439487800003 | - |