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- Publisher Website: 10.1016/j.jcmgh.2022.01.017
- Scopus: eid_2-s2.0-85126628685
- PMID: 35093589
- WOS: WOS:000986860300001
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Article: FACI Is a Novel CREB-H–Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity
Title | FACI Is a Novel CREB-H–Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity |
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Authors | |
Keywords | Lipid Homeostasis Phospholipid-Binding Protein Recycling Endosome Intestinal Fat Absorption Metabolic Syndrome |
Issue Date | 2022 |
Publisher | Elsevier: Open Access Journals. The Journal's web site is located at https://www.cmghjournal.org/ |
Citation | Cellular and Molecular Gastroenterology and Hepatology, 2022, v. 13 n. 5, p. 1365-1391 How to Cite? |
Abstract | CREB-H is a key regulator of lipid homeostasis. We identified fasting- and CREB-H–induced protein as a CREB-H–induced membrane and endosomal protein that binds to phospholipids. Using Faci-deficient mice, we defined a new function of fasting- and CREB-H–induced protein in the inhibition of intestinal lipid absorption and reversal of obesity. |
Persistent Identifier | http://hdl.handle.net/10722/312929 |
ISSN | 2023 Impact Factor: 7.1 2023 SCImago Journal Rankings: 2.702 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Cheng, Y | - |
dc.contributor.author | Kang, X | - |
dc.contributor.author | Cheng, T | - |
dc.contributor.author | Ye, ZW | - |
dc.contributor.author | Tipoe, GL | - |
dc.contributor.author | Yu, C | - |
dc.contributor.author | Wong, CM | - |
dc.contributor.author | Liu, B | - |
dc.contributor.author | Chan, CP | - |
dc.contributor.author | Jin, DY | - |
dc.date.accessioned | 2022-05-21T11:53:37Z | - |
dc.date.available | 2022-05-21T11:53:37Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Cellular and Molecular Gastroenterology and Hepatology, 2022, v. 13 n. 5, p. 1365-1391 | - |
dc.identifier.issn | 2352-345X | - |
dc.identifier.uri | http://hdl.handle.net/10722/312929 | - |
dc.description.abstract | CREB-H is a key regulator of lipid homeostasis. We identified fasting- and CREB-H–induced protein as a CREB-H–induced membrane and endosomal protein that binds to phospholipids. Using Faci-deficient mice, we defined a new function of fasting- and CREB-H–induced protein in the inhibition of intestinal lipid absorption and reversal of obesity. | - |
dc.language | eng | - |
dc.publisher | Elsevier: Open Access Journals. The Journal's web site is located at https://www.cmghjournal.org/ | - |
dc.relation.ispartof | Cellular and Molecular Gastroenterology and Hepatology | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Lipid Homeostasis | - |
dc.subject | Phospholipid-Binding Protein | - |
dc.subject | Recycling Endosome | - |
dc.subject | Intestinal Fat Absorption | - |
dc.subject | Metabolic Syndrome | - |
dc.title | FACI Is a Novel CREB-H–Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity | - |
dc.type | Article | - |
dc.identifier.email | Cheng, Y: yuncheng@hku.hk | - |
dc.identifier.email | Ye, ZW: zwye@hku.hk | - |
dc.identifier.email | Tipoe, GL: tgeorge@hku.hk | - |
dc.identifier.email | Yu, C: chyu1@hku.hk | - |
dc.identifier.email | Chan, CP: cpchan@hku.hk | - |
dc.identifier.email | Jin, DY: dyjin@hku.hk | - |
dc.identifier.authority | Tipoe, GL=rp00371 | - |
dc.identifier.authority | Yu, C=rp01930 | - |
dc.identifier.authority | Jin, DY=rp00452 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1016/j.jcmgh.2022.01.017 | - |
dc.identifier.pmid | 35093589 | - |
dc.identifier.pmcid | PMC8938335 | - |
dc.identifier.scopus | eid_2-s2.0-85126628685 | - |
dc.identifier.hkuros | 333103 | - |
dc.identifier.volume | 13 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 1365 | - |
dc.identifier.epage | 1391 | - |
dc.identifier.isi | WOS:000986860300001 | - |
dc.publisher.place | United States | - |