File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1038/s41401-021-00647-y
- WOS: WOS:000639768200003
Supplementary
-
Citations:
- Web of Science: 0
- Appears in Collections:
Article: The glycolytic process in endothelial cells and its implications.
Title | The glycolytic process in endothelial cells and its implications. |
---|---|
Authors | |
Issue Date | 2021 |
Publisher | Nature Publishing Group. The Journal's web site is located at http://www.nature.com/aps/index.html |
Citation | Acta Pharmacologica Sinica, 2021, v. 43, p. 251-259 How to Cite? |
Abstract | Endothelial cells play an obligatory role in regulating local vascular tone and maintaining homeostasis in vascular biology. Cell metabolism, converting food to energy in organisms, is the primary self-sustaining mechanism for cell proliferation and reproduction, structure maintenance, and fight-or-flight responses to stimuli. Four major metabolic processes take place in the energy-producing process, including glycolysis, oxidative phosphorylation, glutamine metabolism, and fatty acid oxidation. Among them, glycolysis is the primary energy-producing mechanism in endothelial cells. The present review focused on glycolysis in endothelial cells under both physiological and pathological conditions. Since the switches among metabolic processes precede the functional changes and disease developments, some prophylactic and/or therapeutic strategies concerning the role of glycolysis in cardiovascular disease are discussed |
Persistent Identifier | http://hdl.handle.net/10722/313934 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Leung, SWS | - |
dc.contributor.author | Shi, Y | - |
dc.date.accessioned | 2022-07-05T05:08:29Z | - |
dc.date.available | 2022-07-05T05:08:29Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Acta Pharmacologica Sinica, 2021, v. 43, p. 251-259 | - |
dc.identifier.uri | http://hdl.handle.net/10722/313934 | - |
dc.description.abstract | Endothelial cells play an obligatory role in regulating local vascular tone and maintaining homeostasis in vascular biology. Cell metabolism, converting food to energy in organisms, is the primary self-sustaining mechanism for cell proliferation and reproduction, structure maintenance, and fight-or-flight responses to stimuli. Four major metabolic processes take place in the energy-producing process, including glycolysis, oxidative phosphorylation, glutamine metabolism, and fatty acid oxidation. Among them, glycolysis is the primary energy-producing mechanism in endothelial cells. The present review focused on glycolysis in endothelial cells under both physiological and pathological conditions. Since the switches among metabolic processes precede the functional changes and disease developments, some prophylactic and/or therapeutic strategies concerning the role of glycolysis in cardiovascular disease are discussed | - |
dc.language | eng | - |
dc.publisher | Nature Publishing Group. The Journal's web site is located at http://www.nature.com/aps/index.html | - |
dc.relation.ispartof | Acta Pharmacologica Sinica | - |
dc.rights | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/[insert DOI] | - |
dc.title | The glycolytic process in endothelial cells and its implications. | - |
dc.type | Article | - |
dc.identifier.email | Leung, SWS: swsleung@hku.hk | - |
dc.identifier.authority | Leung, SWS=rp00235 | - |
dc.identifier.doi | 10.1038/s41401-021-00647-y | - |
dc.identifier.hkuros | 333830 | - |
dc.identifier.volume | 43 | - |
dc.identifier.spage | 251 | - |
dc.identifier.epage | 259 | - |
dc.identifier.isi | WOS:000639768200003 | - |