File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Patients with emphysema: Quantitative CT analysis before and after lung volume reduction surgery. Work in progress

TitlePatients with emphysema: Quantitative CT analysis before and after lung volume reduction surgery. Work in progress
Authors
KeywordsComputed tomography (CT), quantitative
Emphysema, pulmonary
Lung, surgery
Lung, ventilation
Issue Date1997
Citation
Radiology, 1997, v. 203, n. 3, p. 705-714 How to Cite?
AbstractPURPOSE: To quantitatively assess the morphologic changes in the lungs after lung volume reduction surgery and determine whether changes at quantitative computed tomography (CT) reflect changes in lung function. MATERIALS AND METHODS: In 10 patients, chest CT images were obtained at full inspiration and expiration before and after surgery. A semiautomated segmentation method was developed to isolate the lung regions and calculate the lung volumes and frequency distribution of attenuation values. The changes in lung volume and attenuation after surgery were compared with clinical findings, and an exploratory evaluation of outcome predictors was conducted. RESULTS: Semiautomated segmentation and quantitative analysis compared favorably with manual techniques, and there was good correlation between the emphysema indexes and percentage predicted forced expiratory volume in 1 second, forced expiratory volume in 1 second/forced vital capacity, and diffusing capacity. The emphysema index decreased from 60% to 38% at inspiration and from 60% to 27% at expiration after surgery. The average CT lung volume decreased from 7.5 to 5.6 L at inspiration (25%) and from 6.4 to 3.8 L (41%) at expiration after surgery and correlated well with measurements at plethysmography. CONCLUSION: Substantial decreases in the lung volumes and emphysema index, increased airflow, possible reexpansion of some remaining lung, and the relation between preoperative quantitative CT indexes and clinical outcome suggest a multifactorial mechanism for improvement seen after surgery.
Persistent Identifierhttp://hdl.handle.net/10722/315911
ISSN
2023 Impact Factor: 12.1
2023 SCImago Journal Rankings: 3.692
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorBae, Kyongtae T.-
dc.contributor.authorSlone, Richard M.-
dc.contributor.authorGierada, David S.-
dc.contributor.authorYusen, Roger D.-
dc.contributor.authorCooper, Joel D.-
dc.date.accessioned2022-08-24T15:48:34Z-
dc.date.available2022-08-24T15:48:34Z-
dc.date.issued1997-
dc.identifier.citationRadiology, 1997, v. 203, n. 3, p. 705-714-
dc.identifier.issn0033-8419-
dc.identifier.urihttp://hdl.handle.net/10722/315911-
dc.description.abstractPURPOSE: To quantitatively assess the morphologic changes in the lungs after lung volume reduction surgery and determine whether changes at quantitative computed tomography (CT) reflect changes in lung function. MATERIALS AND METHODS: In 10 patients, chest CT images were obtained at full inspiration and expiration before and after surgery. A semiautomated segmentation method was developed to isolate the lung regions and calculate the lung volumes and frequency distribution of attenuation values. The changes in lung volume and attenuation after surgery were compared with clinical findings, and an exploratory evaluation of outcome predictors was conducted. RESULTS: Semiautomated segmentation and quantitative analysis compared favorably with manual techniques, and there was good correlation between the emphysema indexes and percentage predicted forced expiratory volume in 1 second, forced expiratory volume in 1 second/forced vital capacity, and diffusing capacity. The emphysema index decreased from 60% to 38% at inspiration and from 60% to 27% at expiration after surgery. The average CT lung volume decreased from 7.5 to 5.6 L at inspiration (25%) and from 6.4 to 3.8 L (41%) at expiration after surgery and correlated well with measurements at plethysmography. CONCLUSION: Substantial decreases in the lung volumes and emphysema index, increased airflow, possible reexpansion of some remaining lung, and the relation between preoperative quantitative CT indexes and clinical outcome suggest a multifactorial mechanism for improvement seen after surgery.-
dc.languageeng-
dc.relation.ispartofRadiology-
dc.subjectComputed tomography (CT), quantitative-
dc.subjectEmphysema, pulmonary-
dc.subjectLung, surgery-
dc.subjectLung, ventilation-
dc.titlePatients with emphysema: Quantitative CT analysis before and after lung volume reduction surgery. Work in progress-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1148/radiology.203.3.9169692-
dc.identifier.pmid9169692-
dc.identifier.scopuseid_2-s2.0-0030916523-
dc.identifier.volume203-
dc.identifier.issue3-
dc.identifier.spage705-
dc.identifier.epage714-
dc.identifier.isiWOS:A1997XA57800022-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats