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Article: Is Coronary Artery Calcium Mass Related to Agatston Score?

TitleIs Coronary Artery Calcium Mass Related to Agatston Score?
Authors
KeywordsCalcification
Computed tomography (CT)
Coronary vessels
Experimental study
Screening
Issue Date2004
Citation
Academic Radiology, 2004, v. 11, n. 3, p. 286-292 How to Cite?
AbstractRationale and Objectives. The objective of this study was to investigate the relationship between the coronary calcium mass and Agatston score measured on multidetector row computed tomography. Materials and Methods. Eighty-three consecutive subjects (60 men and 23 women) referred for coronary screening were examined by prospectively electrocardiogram-triggered sequential mulfidetector row computed tomography scan (4 × 2.5-mm collimation). Their coronary calcium was quantitated by means of the Agatston scoring and mass method. The values of score and mass were transformed by taking the natural logarithm (In(value+ 1)) to reduce skewness. The relationship between the mass and score was analyzed with multiple regression analysis. Results. Fifty-one subjects had a total of 328 calcified lesions detected and measured. The relationship between the calcium mass and score in 51 subjects conformed well to a linear relationship (r2 = 0.96). When analyzed in the total of 328 lesions, the relationship had a good empiric fit with a nonlinear (quadratic) model (r2 = 0.96). The best-fit equation was In(lesion mass+1) = -0.87 + 0.67 × In(lesion score+1) + 0.10 × score+1) - 2.86)2. This relationship was consistent in different coronary vessels and at different heart levels (r2 = 0.96 - 0.99), although there was a higher image noise at lower heart levels (paired t-tests, P < .0001). Conclusion. A nonlinear (quadratic) relationship existed strongly and consistently between coronary calcium mass and score, demonstrating a possible cross-sectional conversion between the two measurements.
Persistent Identifierhttp://hdl.handle.net/10722/315948
ISSN
2023 Impact Factor: 3.8
2023 SCImago Journal Rankings: 1.062
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHong, Cheng-
dc.contributor.authorPilgram, Thomas K.-
dc.contributor.authorZhu, Fang-
dc.contributor.authorBae, Kyongtae T.-
dc.date.accessioned2022-08-24T15:48:42Z-
dc.date.available2022-08-24T15:48:42Z-
dc.date.issued2004-
dc.identifier.citationAcademic Radiology, 2004, v. 11, n. 3, p. 286-292-
dc.identifier.issn1076-6332-
dc.identifier.urihttp://hdl.handle.net/10722/315948-
dc.description.abstractRationale and Objectives. The objective of this study was to investigate the relationship between the coronary calcium mass and Agatston score measured on multidetector row computed tomography. Materials and Methods. Eighty-three consecutive subjects (60 men and 23 women) referred for coronary screening were examined by prospectively electrocardiogram-triggered sequential mulfidetector row computed tomography scan (4 × 2.5-mm collimation). Their coronary calcium was quantitated by means of the Agatston scoring and mass method. The values of score and mass were transformed by taking the natural logarithm (In(value+ 1)) to reduce skewness. The relationship between the mass and score was analyzed with multiple regression analysis. Results. Fifty-one subjects had a total of 328 calcified lesions detected and measured. The relationship between the calcium mass and score in 51 subjects conformed well to a linear relationship (r2 = 0.96). When analyzed in the total of 328 lesions, the relationship had a good empiric fit with a nonlinear (quadratic) model (r2 = 0.96). The best-fit equation was In(lesion mass+1) = -0.87 + 0.67 × In(lesion score+1) + 0.10 × score+1) - 2.86)2. This relationship was consistent in different coronary vessels and at different heart levels (r2 = 0.96 - 0.99), although there was a higher image noise at lower heart levels (paired t-tests, P < .0001). Conclusion. A nonlinear (quadratic) relationship existed strongly and consistently between coronary calcium mass and score, demonstrating a possible cross-sectional conversion between the two measurements.-
dc.languageeng-
dc.relation.ispartofAcademic Radiology-
dc.subjectCalcification-
dc.subjectComputed tomography (CT)-
dc.subjectCoronary vessels-
dc.subjectExperimental study-
dc.subjectScreening-
dc.titleIs Coronary Artery Calcium Mass Related to Agatston Score?-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S1076-6332(03)00714-1-
dc.identifier.pmid15035519-
dc.identifier.scopuseid_2-s2.0-1442330151-
dc.identifier.volume11-
dc.identifier.issue3-
dc.identifier.spage286-
dc.identifier.epage292-
dc.identifier.isiWOS:000189277500007-

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