File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Intra- and inter-observer reproducibility of volume measurement of knee cartilage segmented from the OAI MR image set using a novel semi-automated segmentation method

TitleIntra- and inter-observer reproducibility of volume measurement of knee cartilage segmented from the OAI MR image set using a novel semi-automated segmentation method
Authors
KeywordsCartilage segmentation
Knee
MR image
Reproducibility
Volume measurement
Issue Date2009
Citation
Osteoarthritis and Cartilage, 2009, v. 17, n. 12, p. 1589-1597 How to Cite?
AbstractObjective: We developed a semi-automated method based on a graph-cuts algorithm for segmentation and volumetric measurements of the cartilage from high-resolution knee magnetic resonance (MR) images from the Osteoarthritis Initiative (OAI) database and assessed the intra- and inter-observer reproducibility of measurements obtained via this method. Design: MR image sets from 20 subjects of varying Kellgren-Lawrence (KL) grades (from 0 to IV) on fixed flexion knee radiographs were selected from the baseline double-echo and steady-state (DESS) knee MR images in the OAI database (0.B.1 Imaging Data set). Two trained radiologists independently performed the segmentation of knee cartilage twice using the semi-automated method. The volumes of segmented cartilage were computed and compared. The intra- and inter-observer reproducibility were determined by means of the coefficient of variation (CV%) of repeated cartilage segmented volume measurements. The subjects were also divided into the low- (0, I or II) and high-KL (III or IV) groups. The differences in cartilage volume measurements and CV% within and between the observers were tested with t tests. Results: The mean (±SD) intra-observer CV% for the 20 cases was 1.29 (±1.05)% for observer 1 and 1.67 (±1.14)% for observer 2, while the mean (±SD) inter-observer CV% was 1.31 (±1.26)% for session 1 and 1.79 (±1.72)% for session 2. There was no significant difference between the two intra-observer CV%'s (P = 0.272) and between the two inter-observer CV%'s (P = 0.353). The mean intra-observer CV% of the low-KL group was significantly smaller than that for the high-KL group for observer 1 (0.83 vs 1.86%: P = 0.025). The segmentation processing times used by the two observers were significantly different (observer 1 vs 2): (mean 49 ± 12 vs 33 ± 6 min) for session 1 and (49 ± 8 vs 32 ± 8 min) for session 2. Conclusion: The semi-automated graph-cuts method allowed us to segment and measure cartilage from high-resolution 3 T MR images of the knee with high intra- and inter-observer reproducibility in subjects with varying severity of OA. © 2009 Osteoarthritis Research Society International.
Persistent Identifierhttp://hdl.handle.net/10722/316024
ISSN
2023 Impact Factor: 7.2
2023 SCImago Journal Rankings: 2.113
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorBae, K. T.-
dc.contributor.authorShim, H.-
dc.contributor.authorTao, C.-
dc.contributor.authorChang, S.-
dc.contributor.authorWang, J. H.-
dc.contributor.authorBoudreau, R.-
dc.contributor.authorKwoh, C. K.-
dc.date.accessioned2022-08-24T15:48:59Z-
dc.date.available2022-08-24T15:48:59Z-
dc.date.issued2009-
dc.identifier.citationOsteoarthritis and Cartilage, 2009, v. 17, n. 12, p. 1589-1597-
dc.identifier.issn1063-4584-
dc.identifier.urihttp://hdl.handle.net/10722/316024-
dc.description.abstractObjective: We developed a semi-automated method based on a graph-cuts algorithm for segmentation and volumetric measurements of the cartilage from high-resolution knee magnetic resonance (MR) images from the Osteoarthritis Initiative (OAI) database and assessed the intra- and inter-observer reproducibility of measurements obtained via this method. Design: MR image sets from 20 subjects of varying Kellgren-Lawrence (KL) grades (from 0 to IV) on fixed flexion knee radiographs were selected from the baseline double-echo and steady-state (DESS) knee MR images in the OAI database (0.B.1 Imaging Data set). Two trained radiologists independently performed the segmentation of knee cartilage twice using the semi-automated method. The volumes of segmented cartilage were computed and compared. The intra- and inter-observer reproducibility were determined by means of the coefficient of variation (CV%) of repeated cartilage segmented volume measurements. The subjects were also divided into the low- (0, I or II) and high-KL (III or IV) groups. The differences in cartilage volume measurements and CV% within and between the observers were tested with t tests. Results: The mean (±SD) intra-observer CV% for the 20 cases was 1.29 (±1.05)% for observer 1 and 1.67 (±1.14)% for observer 2, while the mean (±SD) inter-observer CV% was 1.31 (±1.26)% for session 1 and 1.79 (±1.72)% for session 2. There was no significant difference between the two intra-observer CV%'s (P = 0.272) and between the two inter-observer CV%'s (P = 0.353). The mean intra-observer CV% of the low-KL group was significantly smaller than that for the high-KL group for observer 1 (0.83 vs 1.86%: P = 0.025). The segmentation processing times used by the two observers were significantly different (observer 1 vs 2): (mean 49 ± 12 vs 33 ± 6 min) for session 1 and (49 ± 8 vs 32 ± 8 min) for session 2. Conclusion: The semi-automated graph-cuts method allowed us to segment and measure cartilage from high-resolution 3 T MR images of the knee with high intra- and inter-observer reproducibility in subjects with varying severity of OA. © 2009 Osteoarthritis Research Society International.-
dc.languageeng-
dc.relation.ispartofOsteoarthritis and Cartilage-
dc.subjectCartilage segmentation-
dc.subjectKnee-
dc.subjectMR image-
dc.subjectReproducibility-
dc.subjectVolume measurement-
dc.titleIntra- and inter-observer reproducibility of volume measurement of knee cartilage segmented from the OAI MR image set using a novel semi-automated segmentation method-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.joca.2009.06.003-
dc.identifier.pmid19577672-
dc.identifier.scopuseid_2-s2.0-70449671258-
dc.identifier.volume17-
dc.identifier.issue12-
dc.identifier.spage1589-
dc.identifier.epage1597-
dc.identifier.isiWOS:000272966700010-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats