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- Publisher Website: 10.1016/j.matlet.2020.127982
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Article: Biomimetic fabrication and characterization of collagen/strontium hydroxyapatite nanocomposite
| Title | Biomimetic fabrication and characterization of collagen/strontium hydroxyapatite nanocomposite |
|---|---|
| Authors | |
| Keywords | Biomimetic Nanocomposites Nanocrystals Strontium hydroxyapatite Type I collagen |
| Issue Date | 2020 |
| Citation | Materials Letters, 2020, v. 274, article no. 127982 How to Cite? |
| Abstract | Strontium-releasing bioactive materials have attracted considerable attention for patients with osteoporotic bone defects due to its ability to stimulate bone formation and decrease bone resorption. In the present study, type I collagen/strontium hydroxyapatite nanocomposite (cSrHA) was fabricated via a non-classical biomimetic mineralization pathway. Mineralized collagen fibrils with nanosized SrHA embedded in intrafibrillar interstices were obtained using poly(acrylic acid) as a biomimetic mineralizing director. The resultant nanocomposite was characterized by SEM, TEM, EDS, ATR-FTIR, XRD and TGA. cSrHA displayed morphologies, nanostructures and characteristics similar to those of natural hard tissue and calcium hydroxyapatite-mineralized collagen (cCaHA), indicating its potential value as a biofunctional material for bone engineering. |
| Persistent Identifier | http://hdl.handle.net/10722/318827 |
| ISSN | 2021 Impact Factor: 3.574 2020 SCImago Journal Rankings: 0.755 |
| ISI Accession Number ID |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Qi, Yipin | - |
| dc.contributor.author | Mai, Sui | - |
| dc.contributor.author | Ye, Zhou | - |
| dc.contributor.author | Aparicio, Conrado | - |
| dc.date.accessioned | 2022-10-11T12:24:39Z | - |
| dc.date.available | 2022-10-11T12:24:39Z | - |
| dc.date.issued | 2020 | - |
| dc.identifier.citation | Materials Letters, 2020, v. 274, article no. 127982 | - |
| dc.identifier.issn | 0167-577X | - |
| dc.identifier.uri | http://hdl.handle.net/10722/318827 | - |
| dc.description.abstract | Strontium-releasing bioactive materials have attracted considerable attention for patients with osteoporotic bone defects due to its ability to stimulate bone formation and decrease bone resorption. In the present study, type I collagen/strontium hydroxyapatite nanocomposite (cSrHA) was fabricated via a non-classical biomimetic mineralization pathway. Mineralized collagen fibrils with nanosized SrHA embedded in intrafibrillar interstices were obtained using poly(acrylic acid) as a biomimetic mineralizing director. The resultant nanocomposite was characterized by SEM, TEM, EDS, ATR-FTIR, XRD and TGA. cSrHA displayed morphologies, nanostructures and characteristics similar to those of natural hard tissue and calcium hydroxyapatite-mineralized collagen (cCaHA), indicating its potential value as a biofunctional material for bone engineering. | - |
| dc.language | eng | - |
| dc.relation.ispartof | Materials Letters | - |
| dc.subject | Biomimetic | - |
| dc.subject | Nanocomposites | - |
| dc.subject | Nanocrystals | - |
| dc.subject | Strontium hydroxyapatite | - |
| dc.subject | Type I collagen | - |
| dc.title | Biomimetic fabrication and characterization of collagen/strontium hydroxyapatite nanocomposite | - |
| dc.type | Article | - |
| dc.description.nature | link_to_subscribed_fulltext | - |
| dc.identifier.doi | 10.1016/j.matlet.2020.127982 | - |
| dc.identifier.scopus | eid_2-s2.0-85085236955 | - |
| dc.identifier.volume | 274 | - |
| dc.identifier.spage | article no. 127982 | - |
| dc.identifier.epage | article no. 127982 | - |
| dc.identifier.eissn | 1873-4979 | - |
| dc.identifier.isi | WOS:000541705400004 | - |