File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Changing pattern of pediatric anaphylaxis in Hong Kong, 2010-2019

TitleChanging pattern of pediatric anaphylaxis in Hong Kong, 2010-2019
Authors
Issue Date2022
Citation
Pediatr Allergy Immunol, 2022, v. 33 n. 1, p. e13685 How to Cite?
AbstractBACKGROUND: Anaphylaxis is a significant health burden in most Western countries, but there are little published data on the incidence and pattern of anaphylaxis in Asia. We aim to determine the incidence rate and pattern of anaphylaxis over the past decade among the pediatric population in Hong Kong. METHODS: Medical records of patients presenting with allergy-related symptoms during the period 2010 to 2019 were examined. Pediatric patients aged below 18 years who fulfilled the diagnostic criteria for anaphylaxis laid out by the NIAID/FAAN were analyzed. Incidence rates were calculated using population statistics as the denominator. All information pertaining to the anaphylaxis events and patients' characteristics was retrieved using standardized data collection forms. RESULTS: The overall 10-year estimated incidence of anaphylaxis was 9.76 per 100,000 person-years, with a rising trend of anaphylaxis incidence across time. Food-induced anaphylaxis accounted for the majority of hospital presentations, of which peanut and shellfish were the top food triggers in our population. Majority of anaphylaxis episodes were of Grade 4 severity, and young age was a significant predictor of severe allergic reactions. Half of the anaphylaxis episodes were misdiagnosed and adrenaline was only utilized in 42.2% of cases, of which 9.4% were administered adrenaline prior to hospital arrival. CONCLUSIONS: An increasing trend of anaphylaxis incidence over the past decade is evident in Hong Kong children, with a discrepantly low accuracy in diagnosis and suboptimal management of anaphylaxis. There is a pressing need to heighten public and physicians' awareness of the distinctive features of anaphylaxis in the pediatric age-group.
Persistent Identifierhttp://hdl.handle.net/10722/320271
ISSN
2023 Impact Factor: 4.3
2023 SCImago Journal Rankings: 1.050
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLeung, ASY-
dc.contributor.authorLi, RMY-
dc.contributor.authorAu, AWS-
dc.contributor.authorSou Da Rosa Duque, J-
dc.contributor.authorHo, PKP-
dc.contributor.authorChua, GT-
dc.contributor.authorWong, CH-
dc.contributor.authorLuk, CKD-
dc.contributor.authorKwan, YW-
dc.contributor.authorYau, YS-
dc.contributor.authorWong, GWK-
dc.contributor.authorLeung, TF-
dc.date.accessioned2022-10-21T07:50:11Z-
dc.date.available2022-10-21T07:50:11Z-
dc.date.issued2022-
dc.identifier.citationPediatr Allergy Immunol, 2022, v. 33 n. 1, p. e13685-
dc.identifier.issn0905-6157-
dc.identifier.urihttp://hdl.handle.net/10722/320271-
dc.description.abstractBACKGROUND: Anaphylaxis is a significant health burden in most Western countries, but there are little published data on the incidence and pattern of anaphylaxis in Asia. We aim to determine the incidence rate and pattern of anaphylaxis over the past decade among the pediatric population in Hong Kong. METHODS: Medical records of patients presenting with allergy-related symptoms during the period 2010 to 2019 were examined. Pediatric patients aged below 18 years who fulfilled the diagnostic criteria for anaphylaxis laid out by the NIAID/FAAN were analyzed. Incidence rates were calculated using population statistics as the denominator. All information pertaining to the anaphylaxis events and patients' characteristics was retrieved using standardized data collection forms. RESULTS: The overall 10-year estimated incidence of anaphylaxis was 9.76 per 100,000 person-years, with a rising trend of anaphylaxis incidence across time. Food-induced anaphylaxis accounted for the majority of hospital presentations, of which peanut and shellfish were the top food triggers in our population. Majority of anaphylaxis episodes were of Grade 4 severity, and young age was a significant predictor of severe allergic reactions. Half of the anaphylaxis episodes were misdiagnosed and adrenaline was only utilized in 42.2% of cases, of which 9.4% were administered adrenaline prior to hospital arrival. CONCLUSIONS: An increasing trend of anaphylaxis incidence over the past decade is evident in Hong Kong children, with a discrepantly low accuracy in diagnosis and suboptimal management of anaphylaxis. There is a pressing need to heighten public and physicians' awareness of the distinctive features of anaphylaxis in the pediatric age-group.-
dc.languageeng-
dc.relation.ispartofPediatr Allergy Immunol-
dc.titleChanging pattern of pediatric anaphylaxis in Hong Kong, 2010-2019-
dc.typeArticle-
dc.identifier.emailSou Da Rosa Duque, J: jsrduque@hku.hk-
dc.identifier.authoritySou Da Rosa Duque, J=rp02340-
dc.identifier.authorityChua, GT=rp02684-
dc.identifier.doi10.1111/pai.13685-
dc.identifier.hkuros340213-
dc.identifier.volume33-
dc.identifier.issue1-
dc.identifier.spagee13685-
dc.identifier.epagee13685-
dc.identifier.isiWOS:000712945400001-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats