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- Publisher Website: 10.1016/j.jcv.2007.09.013
- Scopus: eid_2-s2.0-40849094625
- PMID: 18191614
- WOS: WOS:000255209100009
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Article: High prevalence of HCV in a cohort of injectors on methadone substitution treatment
Title | High prevalence of HCV in a cohort of injectors on methadone substitution treatment |
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Authors | |
Keywords | HCV Hong Kong IDU Methadone |
Issue Date | 2008 |
Citation | Journal of Clinical Virology, 2008, v. 41, n. 4, p. 297-300 How to Cite? |
Abstract | Background: In Hong Kong, methadone treatment is widely accessible. Injecting drug users (IDU) have a relatively low risk behavioural profile and low HIV prevalence (0.3%). The corresponding Hepatitis C (HCV) level, however, is unclear. Objectives: To determine the HCV prevalence in IDU in Hong Kong and to identify any associated factors. Study Design: A community-based HCV prevalence study of IDU was conducted in methadone clinics. Demographics and drug use pattern were collected through a questionnaire survey and blood samples were obtained for HCV serological tests. Results: Data of 567 IDU were analyzed. Most were male (84%) and ethnic Chinese (98%). The median age was 49 years and median injection duration 17 years. Two-thirds (62%) admitted ever sharing injecting equipments. Most (76%) reported having injection drug use in the preceding 3 months, and 44% abused midazolam/triazolam in addition to heroin. Prevalence of HCV antibodies was 85% (95% confidence interval 82.5-88.3%). Injection duration, recent injection, ever sharing injecting equipments and concomitant use of other drugs were independent factors associated with HCV infection. Conclusions: HCV prevalence is high in IDU despite a low HIV prevalence and widely available substitution treatment, which has probably slowed but not prevented the HCV epidemic in IDU in Hong Kong. © 2007 Elsevier B.V. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/323815 |
ISSN | 2023 Impact Factor: 4.0 2023 SCImago Journal Rankings: 1.344 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lee, Krystal C.K. | - |
dc.contributor.author | Lim, Wilina W.L. | - |
dc.contributor.author | Lee, Shui Shan | - |
dc.date.accessioned | 2023-01-13T02:59:31Z | - |
dc.date.available | 2023-01-13T02:59:31Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | Journal of Clinical Virology, 2008, v. 41, n. 4, p. 297-300 | - |
dc.identifier.issn | 1386-6532 | - |
dc.identifier.uri | http://hdl.handle.net/10722/323815 | - |
dc.description.abstract | Background: In Hong Kong, methadone treatment is widely accessible. Injecting drug users (IDU) have a relatively low risk behavioural profile and low HIV prevalence (0.3%). The corresponding Hepatitis C (HCV) level, however, is unclear. Objectives: To determine the HCV prevalence in IDU in Hong Kong and to identify any associated factors. Study Design: A community-based HCV prevalence study of IDU was conducted in methadone clinics. Demographics and drug use pattern were collected through a questionnaire survey and blood samples were obtained for HCV serological tests. Results: Data of 567 IDU were analyzed. Most were male (84%) and ethnic Chinese (98%). The median age was 49 years and median injection duration 17 years. Two-thirds (62%) admitted ever sharing injecting equipments. Most (76%) reported having injection drug use in the preceding 3 months, and 44% abused midazolam/triazolam in addition to heroin. Prevalence of HCV antibodies was 85% (95% confidence interval 82.5-88.3%). Injection duration, recent injection, ever sharing injecting equipments and concomitant use of other drugs were independent factors associated with HCV infection. Conclusions: HCV prevalence is high in IDU despite a low HIV prevalence and widely available substitution treatment, which has probably slowed but not prevented the HCV epidemic in IDU in Hong Kong. © 2007 Elsevier B.V. All rights reserved. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of Clinical Virology | - |
dc.subject | HCV | - |
dc.subject | Hong Kong | - |
dc.subject | IDU | - |
dc.subject | Methadone | - |
dc.title | High prevalence of HCV in a cohort of injectors on methadone substitution treatment | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.jcv.2007.09.013 | - |
dc.identifier.pmid | 18191614 | - |
dc.identifier.scopus | eid_2-s2.0-40849094625 | - |
dc.identifier.volume | 41 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 297 | - |
dc.identifier.epage | 300 | - |
dc.identifier.isi | WOS:000255209100009 | - |