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Article: In vivo evaluation and characterization of a bio-absorbable drug-coated stent fabricated using a 3D-printing system

TitleIn vivo evaluation and characterization of a bio-absorbable drug-coated stent fabricated using a 3D-printing system
Authors
Keywords3D-printing
Bio-absorbable stent
Biodegradable polymer
Coronary stent
Drug-eluting stent
Issue Date2015
Citation
Materials Letters, 2015, v. 141, p. 355-358 How to Cite?
AbstractIn this study, we prepared a helical, biocompatible, and biodegradable stent by 3D rapid prototyping. The fabricated polycaprolactone (PCL) stent was coated with sirolimus mixed with poly-(lactide-co-glycolide) (PLGA), and polyethylene glycol (PEG), via a spraying method for slow drug release. The engineered, drug-eluting, bio-absorbable vascular stent (BVS) was analyzed and tested in vivo, and proving effective in animal experiments. These findings suggest that our new approach is useful for treating coronary thrombosis, and it may provide a promising scaffold for developing biological stent technology.
Persistent Identifierhttp://hdl.handle.net/10722/323926
ISSN
2023 Impact Factor: 2.7
2023 SCImago Journal Rankings: 0.602
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorPark, Su A.-
dc.contributor.authorLee, Sang Jin-
dc.contributor.authorLim, Kyung Seob-
dc.contributor.authorBae, In Ho-
dc.contributor.authorLee, Jun Hee-
dc.contributor.authorKim, Wan Doo-
dc.contributor.authorJeong, Myung Ho-
dc.contributor.authorPark, Jun Kyu-
dc.date.accessioned2023-01-13T03:00:17Z-
dc.date.available2023-01-13T03:00:17Z-
dc.date.issued2015-
dc.identifier.citationMaterials Letters, 2015, v. 141, p. 355-358-
dc.identifier.issn0167-577X-
dc.identifier.urihttp://hdl.handle.net/10722/323926-
dc.description.abstractIn this study, we prepared a helical, biocompatible, and biodegradable stent by 3D rapid prototyping. The fabricated polycaprolactone (PCL) stent was coated with sirolimus mixed with poly-(lactide-co-glycolide) (PLGA), and polyethylene glycol (PEG), via a spraying method for slow drug release. The engineered, drug-eluting, bio-absorbable vascular stent (BVS) was analyzed and tested in vivo, and proving effective in animal experiments. These findings suggest that our new approach is useful for treating coronary thrombosis, and it may provide a promising scaffold for developing biological stent technology.-
dc.languageeng-
dc.relation.ispartofMaterials Letters-
dc.subject3D-printing-
dc.subjectBio-absorbable stent-
dc.subjectBiodegradable polymer-
dc.subjectCoronary stent-
dc.subjectDrug-eluting stent-
dc.titleIn vivo evaluation and characterization of a bio-absorbable drug-coated stent fabricated using a 3D-printing system-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.matlet.2014.11.119-
dc.identifier.scopuseid_2-s2.0-84917706119-
dc.identifier.volume141-
dc.identifier.spage355-
dc.identifier.epage358-
dc.identifier.eissn1873-4979-
dc.identifier.isiWOS:000348263300093-

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