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- Publisher Website: 10.1016/j.matlet.2014.11.119
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Article: In vivo evaluation and characterization of a bio-absorbable drug-coated stent fabricated using a 3D-printing system
Title | In vivo evaluation and characterization of a bio-absorbable drug-coated stent fabricated using a 3D-printing system |
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Authors | |
Keywords | 3D-printing Bio-absorbable stent Biodegradable polymer Coronary stent Drug-eluting stent |
Issue Date | 2015 |
Citation | Materials Letters, 2015, v. 141, p. 355-358 How to Cite? |
Abstract | In this study, we prepared a helical, biocompatible, and biodegradable stent by 3D rapid prototyping. The fabricated polycaprolactone (PCL) stent was coated with sirolimus mixed with poly-(lactide-co-glycolide) (PLGA), and polyethylene glycol (PEG), via a spraying method for slow drug release. The engineered, drug-eluting, bio-absorbable vascular stent (BVS) was analyzed and tested in vivo, and proving effective in animal experiments. These findings suggest that our new approach is useful for treating coronary thrombosis, and it may provide a promising scaffold for developing biological stent technology. |
Persistent Identifier | http://hdl.handle.net/10722/323926 |
ISSN | 2023 Impact Factor: 2.7 2023 SCImago Journal Rankings: 0.602 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Park, Su A. | - |
dc.contributor.author | Lee, Sang Jin | - |
dc.contributor.author | Lim, Kyung Seob | - |
dc.contributor.author | Bae, In Ho | - |
dc.contributor.author | Lee, Jun Hee | - |
dc.contributor.author | Kim, Wan Doo | - |
dc.contributor.author | Jeong, Myung Ho | - |
dc.contributor.author | Park, Jun Kyu | - |
dc.date.accessioned | 2023-01-13T03:00:17Z | - |
dc.date.available | 2023-01-13T03:00:17Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Materials Letters, 2015, v. 141, p. 355-358 | - |
dc.identifier.issn | 0167-577X | - |
dc.identifier.uri | http://hdl.handle.net/10722/323926 | - |
dc.description.abstract | In this study, we prepared a helical, biocompatible, and biodegradable stent by 3D rapid prototyping. The fabricated polycaprolactone (PCL) stent was coated with sirolimus mixed with poly-(lactide-co-glycolide) (PLGA), and polyethylene glycol (PEG), via a spraying method for slow drug release. The engineered, drug-eluting, bio-absorbable vascular stent (BVS) was analyzed and tested in vivo, and proving effective in animal experiments. These findings suggest that our new approach is useful for treating coronary thrombosis, and it may provide a promising scaffold for developing biological stent technology. | - |
dc.language | eng | - |
dc.relation.ispartof | Materials Letters | - |
dc.subject | 3D-printing | - |
dc.subject | Bio-absorbable stent | - |
dc.subject | Biodegradable polymer | - |
dc.subject | Coronary stent | - |
dc.subject | Drug-eluting stent | - |
dc.title | In vivo evaluation and characterization of a bio-absorbable drug-coated stent fabricated using a 3D-printing system | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.matlet.2014.11.119 | - |
dc.identifier.scopus | eid_2-s2.0-84917706119 | - |
dc.identifier.volume | 141 | - |
dc.identifier.spage | 355 | - |
dc.identifier.epage | 358 | - |
dc.identifier.eissn | 1873-4979 | - |
dc.identifier.isi | WOS:000348263300093 | - |