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- Publisher Website: 10.1007/978-3-7091-6475-4_43
- Scopus: eid_2-s2.0-0032239491
- PMID: 9779169
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Article: CSF Antibiotic Prophylaxis for Neurosurgical Patients with Ventriculostomy: A Randomised Study
Title | CSF Antibiotic Prophylaxis for Neurosurgical Patients with Ventriculostomy: A Randomised Study |
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Authors | |
Keywords | Antibiotic prophylaxis Ventriculostomy |
Issue Date | 1998 |
Citation | Acta Neurochirurgica, Supplement, 1998, v. 1998, n. SUPPL. 71, p. 146-148 How to Cite? |
Abstract | The value of prophylactic antibiotics for patients with ventricular catheter for monitoring and CSF drainage is uncertain. 228 patients were randomised to receive perioperative antibiotics only (Unasyn, Group I) or prolonged antibiotics for the presence of the ventricular catheter (Unasyn and Aztreonam, Group II). The incidence of intracranial and extracranial infection was documented prospectively. Group II patients had a significantly reduced incidence of CSF infection [3/115 (3%) vs 12/113 (11%), p = 0.01] and extracranial infections [23/115 (20%) vs 48/113 (42%), p = 0.002]. CSF pathogens in Group II patients were MRSA and Candida, whereas in Group I, Staphylococci, E coli and Klebsiella. Although prolonged antibiotic prophylaxis significantly reduced the incidence of serious CSF infection as well as extracranial infections, this policy did select resistant or opportunistic pathogens such as Candida and MRSA. |
Persistent Identifier | http://hdl.handle.net/10722/325018 |
ISSN | 2019 SCImago Journal Rankings: 0.320 |
DC Field | Value | Language |
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dc.contributor.author | Poon, W. S. | - |
dc.contributor.author | Ng, S. | - |
dc.contributor.author | Wai, S. | - |
dc.date.accessioned | 2023-02-27T07:29:02Z | - |
dc.date.available | 2023-02-27T07:29:02Z | - |
dc.date.issued | 1998 | - |
dc.identifier.citation | Acta Neurochirurgica, Supplement, 1998, v. 1998, n. SUPPL. 71, p. 146-148 | - |
dc.identifier.issn | 0065-1419 | - |
dc.identifier.uri | http://hdl.handle.net/10722/325018 | - |
dc.description.abstract | The value of prophylactic antibiotics for patients with ventricular catheter for monitoring and CSF drainage is uncertain. 228 patients were randomised to receive perioperative antibiotics only (Unasyn, Group I) or prolonged antibiotics for the presence of the ventricular catheter (Unasyn and Aztreonam, Group II). The incidence of intracranial and extracranial infection was documented prospectively. Group II patients had a significantly reduced incidence of CSF infection [3/115 (3%) vs 12/113 (11%), p = 0.01] and extracranial infections [23/115 (20%) vs 48/113 (42%), p = 0.002]. CSF pathogens in Group II patients were MRSA and Candida, whereas in Group I, Staphylococci, E coli and Klebsiella. Although prolonged antibiotic prophylaxis significantly reduced the incidence of serious CSF infection as well as extracranial infections, this policy did select resistant or opportunistic pathogens such as Candida and MRSA. | - |
dc.language | eng | - |
dc.relation.ispartof | Acta Neurochirurgica, Supplement | - |
dc.subject | Antibiotic prophylaxis | - |
dc.subject | Ventriculostomy | - |
dc.title | CSF Antibiotic Prophylaxis for Neurosurgical Patients with Ventriculostomy: A Randomised Study | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1007/978-3-7091-6475-4_43 | - |
dc.identifier.pmid | 9779169 | - |
dc.identifier.scopus | eid_2-s2.0-0032239491 | - |
dc.identifier.volume | 1998 | - |
dc.identifier.issue | SUPPL. 71 | - |
dc.identifier.spage | 146 | - |
dc.identifier.epage | 148 | - |